Otago 运动方案改善老年住院衰弱及衰弱前期患者衰弱状态与躯体功能的随机对照研究

doi:10.3969/j.issn.1003-9198.2026.03.010

Abstract

Abstract: Objective To explore the effects of 12-week Otago exercise program (OEP) on frailty degree, fall risk, balance ability, gait function, lower limb function, and body composition in the elderly inpatients with frailty or pre-frailty. Methods A total of 110 elderly patients with frailty and pre-frailty who were hospitalized in West China Hospital of Sichuan University were enrolled in the study. They were randomly divided into an observation group and a control group, with 55 cases in each group. The control group received routine nursing care and health education; the observation group underwent 12 weeks of OEP in addition to routine nursing care. The scores of FRAIL scale, fall risk score, Tinetti score, Simple Physical Performance Bureau (SPPB) score and body composition index were observed and compared between the two groups before and after 12 weeks of intervention. Results After 12 weeks of intervention, the scores of FRAIL scale and fall risk and the fat content of the body in the observation group were significantly lower than those in the control group (P<0.05); The Tinetti score, SPPB score, and skeletal muscle mass in the observation group were higher than those in the control group (P<0.05). Conclusions OEP can effectively improve the frailty status of elderly patients with frailty or pre-frailty, reduce the risk of falls, and enhance balance ability and muscle mass, which is an effective comprehensive strategy for optimizing the management of frail elderly inpatients.

Key words: aged, inpatient, frailty, Otago exercise, physical function

CLC Number:

R 592

FAN Tingyong, HUANG Zhaojing, PENG Chunlan, LIU Hong, WANG Yao, LIU Xin. A randomized controlled study on Otago exercise program improving frailty status and physical function in elderly inpatients with frailty or pre-frailty[J]. Practical Geriatrics, 2026, 40(3): 272-277.

References

[1] COHEN C I, BENYAMINOV R, RAHMAN M, et al. Frailty: a multidimensional biopsychosocial syndrome[J]. Med Clin North Am, 2023, 107(1): 183-197.
[2] O’CAOIMH R, SEZGIN D, O’DONOVAN M R, et al. Prevalence of frailty in 62 countries across the world: a systematic review and meta-analysis of population-level studies[J]. Age Ageing, 2021, 50(1): 96-104.
[3] 陶代娣. 老年住院共病患者衰弱状况及其危险因素研究[D]. 合肥: 安徽医科大学, 2022.
[4] DENT E, MARTIN F C, BERGMAN H, et al. Management of frailty: opportunities, challenges, and future directions[J]. Lancet, 2019, 394(10206): 1376-1386.
[5] SHERRINGTON C, FAIRHALL N J, WALLBANK G K, et al. Exercise for preventing falls in older people living in the community[J]. Cochrane Database Syst Rev, 2019, 1(1): CD012424.
[6] THOMAS E, BATTAGLIA G, PATTI A, et al. Physical activity programs for balance and fall prevention in elderly: a systematic review[J]. Medicine: Baltimore, 2019, 98(27): e16218.
[7] 中华医学会老年医学分会, 《中华老年医学杂志》编辑委员会. 老年人衰弱预防中国专家共识(2022) [J]. 中华老年医学杂志, 2022, 41(5): 503-511.
[8] 中华医学会老年医学分会. 老年患者衰弱评估与干预中国专家共识 [J]. 中华老年医学杂志, 2017, 36(3): 251-256.
[9] CAMPBELL A J, ROBERTSON M C, GARDNER M M, et al. Randomised controlled trial of a general practice programme of home based exercise to prevent falls in elderly women[J]. BMJ, 1997, 315(7115): 1065-1069.
[10] 刘坤, 黄浩, 朱红, 等. 华西跌倒风险评估量表与托马斯跌倒风险评估量表对老年住院病人跌倒的预测价值[J]. 护理研究, 2021, 35(9): 1516-1520.
[11] BOUCHAM M, SALHI A, EL HAJJI N, et al. Factors associated with frailty in older people: an umbrella review[J]. BMC Geriatr, 2024, 24(1): 737.
[12] KEEBLE E, PARKER S G, ARORA S, et al. Frailty, hospital use and mortality in the older population: findings from the Newcastle 85+ study[J]. Age Ageing, 2019, 48(6): 797-802.
[13] VERONESE N, CUSTODERO C, CELLA A, et al. Prevalence of multidimensional frailty and pre-frailty in older people in different settings: a systematic review and meta-analysis[J]. Ageing Res Rev, 2021, 72: 101498.
[14] ALBORNOS-MUÑOZ L, MORENO-CASBAS M T, SÁNCHEZ-PABLO C, et al. Efficacy of the Otago Exercise Programme to reduce falls in community-dwelling adults aged 65-80 years old when delivered as group or individual training[J]. J Adv Nurs, 2018, 74(7): 1700-1711.
[15] XU X, WEN Z. The mediating role of inflammaging between mitochondrial dysfunction and sarcopenia in aging: a review[J]. Am J Clin Exp Immunol, 2023, 12(6): 109-126.
[16] ANGULO J, EL ASSAR M, ÁLVAREZ-BUSTOS A, et al. Physical activity and exercise: strategies to manage frailty[J]. Redox Biol, 2020, 35: 101513.
[17] LAI X, BO L, ZHU H, et al. Effects of lower limb resistance exercise on muscle strength, physical fitness, and metabolism in pre-frail elderly patients: a randomized controlled trial[J]. BMC Geriatr, 2021, 21(1): 447.
[18] YI M, ZHANG W, ZHANG X, et al. The effectiveness of Otago exercise program in older adults with frailty or pre-frailty: a systematic review and meta-analysis[J]. Arch Gerontol Geriatr, 2023, 114: 105083.
[19] CHEN N, HE X, FENG Y, et al. Effects of resistance training in healthy older people with sarcopenia: a systematic review and meta-analysis of randomized controlled trials[J]. Eur Rev Aging Phys Act, 2021, 18(1): 23.
[20] YANG Y, WANG K, LIU H, et al. The impact of Otago exercise programme on the prevention of falls in older adult: a systematic review[J]. Front Public Health, 2022, 10: 953593.
[21] KOCIC M, STOJANOVIC Z, NIKOLIC D, et al. The effectiveness of group Otago exercise program on physical function in nursing home residents older than 65 years: a randomized controlled trial[J]. Arch Gerontol Geriatr, 2018, 75: 112-118.
[22] 赵亚男, 卢冬磊, 谭思洁. 运动干预老年人的肌少性肥胖[J]. 中国组织工程研究, 2025, 29(17): 3657-3667.
[23] JI T, LI Y, MA L. Sarcopenic obesity: an emerging public health problem[J]. Aging Dis, 2022, 13(2): 379-388.
[24] ZHANG L, LV J, WANG C, et al. Myokine, a key cytokine for physical exercise to alleviate sarcopenic obesity[J]. Mol Biol Rep, 2023, 50(3): 2723-2734.
[25] LEE J, YOO H N, LEE B H. Effects of augmented reality-based Otago exercise on balance, gait, and physical factors in elderly women to prevent falls: a randomized controlled trial[J]. J Phys Ther Sci, 2017, 29(9): 1586-1589.
[26] LEE S Y, CHOO P L, PANG B W J, et al. SPPB reference values and performance in assessing sarcopenia in community-dwelling singaporeans-Yishun Study [J]. BMC Geriatr, 2021, 21(1): 213.
[27] TARAZONA-SANTABALBINA F J, GÓMEZ-CABRERA M C, PÉREZ-ROS P, et al. A multicomponent exercise intervention that reverses frailty and improves cognition, emotion, and social networking in the community-dwelling frail elderly: a randomized clinical trial[J]. J Am Med Dir Assoc, 2016, 17(5): 426-433.
[28] GARCÍA-GOLLARTE F, MORA-CONCEPCIÓN A, PINAZO-HERNANDIS S, et al. Effectiveness of a supervised group-based otago exercise program on functional performance in frail institutionalized older adults: a multicenter randomized controlled trial[J]. J Geriatr Phys Ther, 2023, 46(1): 15-25.

A randomized controlled study on Otago exercise program improving frailty status and physical function in elderly inpatients with frailty or pre-frailty

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