Abstract: Objective To explore the clinical efficacy of selective vertebroplasty in treating multiple segment vertebral osteoporotic fractures. Methods Retrospectively collected data from 78 patients diagnosed with multiple segment vertebral osteoporotic fractures in Traditional Chinese Medicine Hospital Affiliated to Xinjiang Medical University from January 2021 to June 2023. Preoperative routine X-ray, CT, and MRI examinations were conducted. Patients were divided into two groups based on their surgical preference: Group A received selective vertebroplasty, while Group B received conventional percutaneous vertebroplasty. General data, total number of fractured vertebrae, intraoperative complications, surgery time, and intraoperative blood loss were collected. Preoperative, intraoperative, and final follow-up visual analogue scale (VAS) scores and Oswestry Disability Index (ODI) were recorded; follow up for 6 months, the occurrence of re-fracture was observed. Results Age, gender, body mass index, postoperative ODI, and preoperative VAS scores between the two groups showed no statistically significant differences (P>0.05). However, there were statistically significant differences in intraoperative and postoperative VAS scores (P<0.05). There were statistically significant differences in surgical time, blood loss, and intraoperative complications between the two groups (P<0.05). Conclusions Selective vertebroplasty for the treatment of multiple-segment osteoporotic fractures has similar efficacy to conventional procedures, with shorter surgery time, less bleeding, and fewer intraoperative complications.

Key words: selective vertebroplasty, multi-segment vertebral osteoporotic fractures, aged