老年脓毒症精准抗菌治疗的思考

doi:10.3969/j.issn.1003-9198.2025.04.004

Abstract

Abstract: Sepsis exhibits high morbidity and mortality among the elderly population, posing a significant public health challenge. Timely and effective anti-infective therapy is the cornerstone of sepsis management. Elderly patients, due to the decline in organ function, multiple comorbidities, complex baseline conditions and high individual heterogeneity, need clear pathogen identification and a grasping of the overall characteristics of sepsis to achieve effective and precise antimicrobial therapy. Furthermore,appropriate therapeutic agents should be selected according to individual circumstances with dynamic monitoring and adjustments, and strict medication management should be implemented. Currently, there is no unified standard antimicrobial therapy regimen for sepsis, so the development of new technologies and medicines in the future is necessary to improve patients’ outcomes.

Key words: sepsis, aged, antimicrobial therapy, precision medicine

CLC Number:

R 631

ZHANG Dian, CHEN Mingquan. Considerations on precision antimicrobial therapy for sepsis in the elderly[J]. Practical Geriatrics, 2025, 39(4): 341-346.

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Considerations on precision antimicrobial therapy for sepsis in the elderly

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