老年慢性呼吸系统疾病的流行病学特征

doi:10.3969/j.issn.1003-9198.2025.03.001

Abstract

Abstract: Chronic respiratory diseases impose a heavy burden on the elderly, which significantly influence their quality of life. This article reviews the epidemiological characteristics and risk factors of some common chronic respiratory diseases, including chronic airway inflammation, lung cancer, idiopathic pulmonary fibrosis and tuberculosis, aiming to provide insights for clinical prevention and treatment of chronic respiratory diseases in the elderly.

Key words: chronic respiratory diseases, epidemiological characteristics, aged

CLC Number:

R 563

LI Xiang, LI Xuan, TIAN Yingxuan. Epidemiological characteristics of chronic respiratory diseases in the elderly[J]. Practical Geriatrics, 2025, 39(3): 217-222.

References

[1] 梁瀚文, 易芳, 陈玥晗, 等. 中国慢性咳嗽流行病学调查的现状与展望[J]. 中华结核和呼吸杂志, 2022, 45(1): 100-106.
[2] CHANGA B, GLOMBW B. Guidelines for evaluating chronic cough in pediatrics: ACCP evidence-based clinical practice guidelines[J]. Chest, 2006, 129(1 Suppl): 260S-283S.
[3] MORICEA H, MILLQVIST E, BIEKSIENE K, et al. ERS guidelines on the diagnosis and treatment of chronic cough in adults and children[J]. Eur Respir J, 2020, 55(1): 1901136.
[4] SONGW J, CHANGY S, FARUQI S, et al. Defining chronic cough: a systematic review of the epidemiological literature[J]. Allergy Asthma Immunol Res, 2016, 8(2): 146.
[5] SONGW J, CHANGY S, FARUQI S, et al. The global epidemiology of chronic cough in adults: a systematic review and meta-analysis[J]. Eur Respir J, 2015, 45(5): 1479-1481.
[6] 李婧辰, 张梅, 李镒冲, 等. 我国40岁及以上人群慢性呼吸系统疾病症状流行现况及影响因素研究[J]. 中华流行病学杂志, 2018, 39(6): 786-791.
[7] LAI K, LONG L, YI F, et al. Age and sex distribution of Chinese chronic cough patients and their relationship with capsaicin cough sensitivity[J]. Allergy Asthma Immunol Res, 2019, 11(6): 871-884.
[8] MORICEA H, JAKESA D, FARUQI S, et al. A worldwide survey of chronic cough: a manifestation of enhanced somatosensory response[J]. Eur Respir J, 2014, 44(5): 1149-1155.
[9] SPANEVELLO A, BEGHÉ B, VISCA D, et al. Chronic cough in adults[J]. Eur J Intern Med, 2020, 78: 8-16.
[10] ANT J, KIMJ W, CHOIE Y, et al. Clinical characteristics of chronic cough in Korea[J]. Tuberc Respir Dis, 2020, 83(1): 31-41.
[11] LAI K, LONG L. Current status and future directions of chronic cough in China[J]. Lung, 2020, 198(1): 23-29.
[12] 李斌恺, 赖克方. 慢性咳嗽的流行病学[J]. 中华结核和呼吸杂志, 2010, 33(1): 62-66.
[13] WILSON D, TAKAHASHI K, PAN G, et al. Respiratory symptoms among residents of a heavy-industry province in China: prevalence and risk factors[J]. Respir Med, 2008, 102(11): 1536-1544.
[14] GUO X, FUJINO Y, CHAI J, et al. The prevalence of subjective symptoms after exposure to arsenic in drinking water in Inner Mongolia, China[J]. J Epidemiol, 2003, 13(4): 211-215.
[15] 赖克方, 黄廉蓉, 陈玥晗, 等. 慢性咳嗽临床研究进展[J]. 中华结核和呼吸杂志, 2023, 46(10): 1022-1027.
[16] 中华医学会呼吸病学分会慢性阻塞性肺疾病学组,中国医师协会呼吸医师分会慢性阻塞性肺疾病工作委员会.慢性阻塞性肺疾病诊治指南(2021年修订版)[J]. 中华结核和呼吸杂志, 2021, 44(3): 170-205.
[17] ADELOYE D, SONG P, ZHU Y, et al. Global, regional, and national prevalence of, and risk factors for, chronic obstructive pulmonary disease (COPD) in 2019: a systematic review and modelling analysis[J]. Lancet Respir Med, 2022, 10(5): 447-458.
[18] WANG C, XU J, YANG L, et al. Prevalence and risk factors of chronic obstructive pulmonary disease in China (the China Pulmonary Health [CPH] study): a national cross-sectional study[J]. Lancet, 2018, 391(10131): 1706-1717.
[19] LIU W, WANG W, LIU J, et al. Trend of mortality and years of life lost due to chronic obstructive pulmonary disease in China and its provinces, 2005-2020[J]. Int J Chron Obstruct Pulmon Dis, 2021, 16: 2973-2981.
[20] PAPAIOANNOU A I, HILLAS G, LOUKIDES S, et al. Mortality prevention as the centre of COPD management[J]. ERJ Open Res, 2024, 10(3): 00850-02023.
[21] CHEN S, KUHN M, PRETTNER K, et al. The global economic burden of chronic obstructive pulmonary disease for 204 countries and territories in 2020-50: a health-augmented macroeconomic modelling study[J]. Lancet Glob Health, 2023, 11(8): e1183-e1193.
[22] ZHOU M, WANG H, ZENG X, et al. Mortality, morbidity, and risk factors in China and its provinces, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017[J]. Lancet, 2019, 394(10204): 1145-1158.
[23] SAFIRI S, CARSON-CHAHHOUD K, NOORI M, et al. Burden of chronic obstructive pulmonary disease and its attributable risk factors in 204 countries and territories, 1990-2019: results from the Global Burden of Disease Study 2019[J]. BMJ, 2022, 378: e069679.
[24] HOLTJER J C S, BLOEMSMAL D, BEIJERS R J H C G, et al. Identifying risk factors for COPD and adult-onset asthma: an umbrella review[J]. Eur Respir Rev, 2023, 32(168): 230009.
[25] 中华医学会, 中华医学会杂志社, 中华医学会全科医学分会,等. 中国慢性阻塞性肺疾病基层诊疗与管理指南(2024年)[J]. 中华全科医师杂志, 2024, 23(6): 578-602.
[26] POLVERINO E, GOEMINNE P C, MCDONNELL M J, et al. European Respiratory Society guidelines for the management of adult bronchiectasis[J]. Eur Respir J, 2017, 50(3): 1700629.
[27] 徐小勇, 施毅. 支气管扩张的诊断和治疗进展[J]. 中国呼吸与危重监护杂志, 2017,16(2): 186-190.
[28] CHALMERS J D, POLVERINO E, CRICHTON M L, et al. Bronchiectasis in Europe: data on disease characteristics from the European Bronchiectasis registry (EMBARC)[J]. Lancet Respir Med, 2023, 11(7): 637-649.
[29] NIGRO M, LASKA I F, TRAVERSI L, et al. Epidemiology of bronchiectasis[J]. Eur Respir Rev, 2024, 33(174): 240091.
[30] FENG J, SUN L, SUN X, et al. Increasing prevalence and burden of bronchiectasis in urban Chinese adults, 2013-2017: a nationwide population-based cohort study[J]. Respir Res, 2022, 23(1): 111.
[31] CHOI H, YANG B, KIM Y J, et al. Increased mortality in patients with non cystic fibrosis bronchiectasis with respiratory comorbidities[J]. Sci Rep, 2021, 11(1): 7126.
[32] MATEUS S P, RIBEIRO-ALVES M, SALLES R E B, et al. Mortality and comorbidities in patients with bronchiectasis over a 3-year follow-up[J]. Medicine, 2022, 101(52): e32537.
[33] ROBERTS J M, GOYAL V, KULARATNA S, et al. The economic burden of bronchiectasis: a systematic review[J]. Chest, 2023, 164(6): 1396-1421.
[34] GUAN W J, GAOY H, XU G, et al. Aetiology of bronchiectasis in Guangzhou, Southern China[J]. Respirology, 2015, 20(5): 739-748.
[35] GÓMEZ-OLIVAS J D, OSCULLO G, MARTÍNEZ-GARCÍA M Á. Etiology of bronchiectasis in the world: data from the published national and international registries[J]. J Clin Med, 2023, 12(18): 5782.
[36] QI Q, XU J, WANG Y, et al. Decreased sphingosine due to down-regulation of acid ceramidase expression in airway of bronchiectasis patients: a potential contributor to Pseudomonas aeruginosa infection[J]. Infect Drug Resist, 2023, 16: 2573-2588.
[37] WANG L L, LU H W, LI L L, et al. Pseudomonas aeruginosa isolation is an important predictor for recurrent hemoptysis after bronchial artery embolization in patients with idiopathic bronchiectasis: a multicenter cohort study[J]. Respir Res, 2023, 24(1): 84.
[38] BRAY F, LAVERSANNE M, SUNG H, et al. Global cancer statistics 2022: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries[J]. CA Cancer J Clin, 2024, 74(3): 229-263.
[39] 郑荣寿, 陈茹, 韩冰峰, 等. 2022年中国恶性肿瘤流行情况分析[J]. 中华肿瘤杂志, 2024, 46(3): 221-231.
[40] CHEN W, ZHENG R, BAADE P D, et al. Cancer statistics in China, 2015[J]. CA A Cancer J Clinicians, 2016, 66(2): 115-132.
[41] YOUNG R P, HOPKINS R J, CHRISTMAS T, et al. COPD prevalence is increased in lung cancer, independent of age, sex and smoking history[J]. Eur Respir J, 2009, 34(2): 380-386.
[42] MCKAY J D, HUNG R J, HAN Y, et al. Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes[J]. Nat Genet, 2017, 49(7): 1126-1132.
[43] SIGEL K, MAKINSON A, THALER J. Lung cancer in persons with HIV[J]. Curr Opin HIV AIDS, 2017, 12(1): 31-38.
[44] XUE X J, GAO Q, QIAO J H, et al. Red and processed meat consumption and the risk of lung cancer: a dose-response meta-analysis of 33 published studies[J]. Int J Clin Exp Med, 2014, 7(6): 1542-1553.
[45] WEI X, ZHU C, JI M, et al. Diet and risk of incident lung cancer: a large prospective cohort study in UK biobank[J]. Am J Clin Nutr, 2021, 114(6): 2043-2051.
[46] 中华医学会呼吸病学分会, 中国医师协会呼吸医师分会. 间质性肺疾病多学科讨论规范中国专家共识[J]. 中华结核和呼吸杂志, 2023, 46(12): 1176-1188.
[47] WIJSENBEEK M, COTTIN V. Spectrum of fibrotic lung diseases[J]. N Engl J Med, 2020, 383(10): 958-968.
[48] FERNÁNDEZ FABRELLAS E, PERIS SÁNCHEZ R, SABATER ABAD C, et al. Prognosis and follow-up of idiopathic pulmonary fibrosis[J]. Med Sci, 2018, 6(2): 51.
[49] LEE J H, PARK H J, KIM S, et al. Epidemiology and comorbidities in idiopathic pulmonary fibrosis: a nationwide cohort study[J]. BMC Pulm Med, 2023, 23(1): 54.
[50] 尹成胜, 张苑, 李惠萍. 特发性肺纤维化急性加重的研究进展[J]. 中华医学杂志, 2019, 99(8): 637-640.
[51] PODOLANCZUK A J, THOMSON C C, REMY-JARDIN M, et al. Idiopathic pulmonary fibrosis: state of the art for 2023[J]. Eur Respir J, 2023, 61(4): 2200957.
[52] GAGNEUX S. Ecology and evolution of Mycobacterium tuberculosis[J]. Nat Rev Microbiol, 2018, 16(4): 202-213.
[53] World Health Organization. Global Tuberculosis Report 2023[R].Geneva:World Health Organization.2023.
[54] World Health Organization. Global Tuberculosis Report 2024[R].Geneva:World Health Organization.2024.
[55] 王歆尧, 姜美丽, 庞元捷, 等. 中国结核病疾病负担现状[J]. 中华流行病学杂志, 2024, 45(6): 857-864.
[56] 中华医学会, 中华医学会杂志社, 中华医学会全科医学分会,等. 肺结核基层诊疗指南(2018年)[J]. 中华全科医师杂志, 2019, 18(8): 709-717.
[57] 中华医学会结核病学分会. 老年肺结核诊断与治疗专家共识(2023版)[J]. 中华结核和呼吸杂志, 2023, 46(11): 1068-1084.
[58] 张梦迪,王鑫,郑文静,等.老年结核病危险因素研究进展[J].中国防痨杂志,2024,46(10):1266-1272.

Epidemiological characteristics of chronic respiratory diseases in the elderly

PDF (PC)

Knowledge

Abstract

Cite this article

share this article

References

Related Articles 15

Metrics

Recommended 0

[1]	WU Ziwen, ZHANG Li. Epidemiological characteristics of chronic neurological diseases in the elderly [J]. Practical Geriatrics, 2025, 39(3): 223-227.
[2]	ZHANG Yiru, WANG Yao, WANG Bin. Epidemiological characteristics and prevention strategies of chronic kidney disease in the elderly in China [J]. Practical Geriatrics, 2025, 39(3): 228-231.
[3]	ZHOU Kaiwen, LAI Piao, WANG Minhong, CHENG Ruoxi, YANG Lijun, WENG Xiaofen, ZHU Gengchao, ZHANG Li. Correlation between serum creatinine-to-cystatin C ratio and physical performance in elderly people [J]. Practical Geriatrics, 2025, 39(3): 232-235.
[4]	ZHANG Yue, LIU Wen, ZHOU Zhiqiang. Correlation between preoperative peripheral inflammation phenotypes and postoperative delirium in elderly patients: a latent class analysis based on inflammatory markers [J]. Practical Geriatrics, 2025, 39(3): 236-240.
[5]	WEI Xiaowei, ZHANG Linzhu, ZHANG Juan, ZHOU Jin. Predictive effect of CONUT score on tolerance of postoperative adjuvant chemotherapy and prognosis in elderly patients with stage Ⅱ/Ⅲ colon cancer [J]. Practical Geriatrics, 2025, 39(3): 241-244.
[6]	LIU Niu, WU Yiyun, ZHOU Zhengguo, DONG Weilu. Comparative study on the diagnosing value of ACR-TIRADS and C-TIRADS for thyroid nodules in elderly [J]. Practical Geriatrics, 2025, 39(3): 245-248.
[7]	WANG Hong, WANG Qing, ZHANG Jianwei, MENG Lijun, TIAN Ting, DENG Hui. Effect of multicomponent exercise in elderly patients with stable chronic obstructive pulmonary disease and frailty [J]. Practical Geriatrics, 2025, 39(3): 249-253.
[8]	JIANG Rui, GAO Yue, DU Wei, YANG Hao, DONG Qingshan, LI Xianjin, LI Shijie, HAN Bing. Effects of discontinuing anticoagulation therapy on long-term prognosis in elderly patients with non-valvular atrial fibrillation [J]. Practical Geriatrics, 2025, 39(3): 254-257.
[9]	LI Guoyuan, LIU Changying, HAO Xiaodan, CHENG Hui, YUAN Shuxuan, CHEN Jieyu, WANG Zhang. Correlation between early dynamic changes of immune cells and pulmonary infection in elderly patients with acute respiratory distress syndrome [J]. Practical Geriatrics, 2025, 39(3): 263-267.
[10]	CUI Yin, ZHANG Fujun, MA Zhengliang, GU Xiaoping. Development trajectory of cognitive function in elderly patients undergoing robot-assisted laparoscopic urological surgery [J]. Practical Geriatrics, 2025, 39(3): 282-285.
[11]	GUO Jing, ZHANG Lixia, ZHENG Juan, XU Hua, CHAI Shujuan. Effects of moderate intensity aerobic exercise on elderly patients with mild to moderate post-stroke depression [J]. Practical Geriatrics, 2025, 39(3): 286-289.
[12]	WANG Xiaoqin, FANG Zhenkun, WU Chenkai, ZHANG Yu. Effect of dietary nutrition literacy on nutritional risk of elderly people in the community [J]. Practical Geriatrics, 2025, 39(3): 290-293.
[13]	LIU Xuande, ZHOU Shigong, XU Zhuqin, SHAN Shoujie. Levels and diagnostic value of serum semaphorin 7A in elderly patients with acute coronary syndrome [J]. Practical Geriatrics, 2025, 39(3): 294-297.
[14]	ZHAO Siyi, LIU Mengya, CHANG Yuqing, GUO Wenjing, ZHANG Meng, ZHANG Li. Cut-off value of grip strength and the relationship with intrinsic capability in Chinese elderly [J]. Practical Geriatrics, 2025, 39(3): 298-302.
[15]	LI Fenhong, WEI Yanan, WU Mengli, SHEN Xiaohui, TANG Leilei. Enhanced recovery after surgery(ERAS) principles in nutritional management for elderly patients with head and neck cancer perioperatively [J]. Practical Geriatrics, 2025, 39(2): 134-138.