预后营养指数对老年女性OVCF病人PVA术后再发椎体骨折的影响

doi:10.3969/j.issn.1003-9198.2023.05.009

Abstract

Abstract: Objective To investigate the prevalence of reoccurrence of vertebral fractures in the elderly female patients with osteoporotic vertebral compression fractures(OVCF) after percutaneous vertebral augmentation(PVA) and the related influencing factors. Methods A total of 205 elderly women with OVCF after PVA were enrolled, and the basic data including age, body mass index(BMI), admission blood count, blood biochemical index and bone mineral density(BMD) were collected. The investigation period was from 2 to 40 months after PVA. The patients were divided into re-fracture group and control group according to whether vertebral re-fracture occurred. The factors influencing the recurrence of vertebral fractures were analyzed by single factor analysis and multivariate Cox regression model, and the predictive value of the independent factors was calculated by Logistic regression, and the receiver operating chavactevistic (ROC) curve was drawn. Results The incidence rate of recurrent vertebral fractures in the elderly women with OVCF after PVA was 20.5%, and prognostic nutritional index(PNI), BMD, age, and the use of anti-osteoporosis drugs were the independent influencing factors of recurrent vertebral fractures after PVA. The risk of re-fracture after PVA was lower in patients with high PNI compared with those with low PNI. There was an interaction between PNI and the use of anti-osteoporosis drugs, and the high PNI group had better efficacy. Compared with the model without PNI, the area of the ROC curve of the model with PNI was increased by 0.065(0.003-0.127). Conclusions High PNI is a protective factor for recurrent vertebral fractures after PVA in the elderly female patients with OVCF, and has predictive value for vertebral re-fracture after PVA, which can reduce the incidence of re-fracture by improving the efficacy of anti-osteoporosis drugs.

Key words: prognostic nutritional index, elderly women, percutaneous vertebral augmentation, osteoporotic vertebral compression fracture

CLC Number:

R 683.2

XU Feng-zhou, GAO Kai-qian, SUN Liang-liang, GAO Xue-feng, ZHANG Xiong, LIU Yong-qiang, ZHOU Jian-wei. Effect of prognostic nutritional index on recurrent vertebral fractures after percutaneous vertebral augmentation in elderly female patients with osteoporotic vertebral compression fractures[J]. Practical Geriatrics, 2023, 37(5): 470-474.

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Effect of prognostic nutritional index on recurrent vertebral fractures after percutaneous vertebral augmentation in elderly female patients with osteoporotic vertebral compression fractures

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