Practical Geriatrics ›› 2025, Vol. 39 ›› Issue (12): 1202-1206.doi: 10.3969/j.issn.1003-9198.2025.12.003

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Diagnostic performance of dual-source photon-counting CT for coronary artery stenosis in elderly patients with severe calcification

JIN Danyan, MAO Xinyu, ZHOU Qijing, LUO Song, XU Xiaojun   

  1. Zhejiang University,Hangzhou 310058, China (JIN Danyan);
    Department of Radiology, Linping Hospital of Integrated Traditional Chinese and Western Medicine, Hangzhou 311100, China (MAO Xinyu);
    Department of Radiology, the Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310009, China (ZHOU Qijing, XU Xiaojun);
    Department of Radiology,Geriatric Hospital of Nanjing Medical University, Nanjing 210024, China (LUO Song)
  • Received:2025-09-15 Published:2025-12-26
  • Contact: XU Xiaojun, Email: xxjmailbox@zju.edu.cn

Abstract: Objective To explore the diagnostic performance and clinical application value of dual-source photon-counting computed tomography (PCCT) coronary angiography for detecting coronary artery obstructive stenosis in elderly patients with severe coronary artery calcification. Methods This study continuously enrolled 41 elderly patients (aged ≥ 65 years; 94 blood vessels) who were clinically suspected or diagnosed with coronary heart disease and underwent PCCT coronary artery imaging at the Second Affiliated Hospital of Zhejiang University School of Medicine from September 2024 to February 2025, with a calcification score ≥400, and underwent invasive coronary angiography (ICA) within 2 weeks after PCCT. The diagnostic efficacy of PCCT for coronary obstructive stenosis was evaluated by using ICA results as the gold standard. Results The average age of the patients was 72.95±5.32 years old, including 26 male patients (63.4%). The mean calcification score was 936.99±600.41. At the patient level, the sensitivity, specificity, positive predictive value, negative predictive value and accuracy of PCCT in the diagnosis of coronary obstructive stenosis were 100.0%, 33.3%, 95.0%, 100.0% and 95.1%, respectively. At the vessel level, the corresponding values were 98.7%, 58.8%, 91.6%, 90.9% and 91.5%, respectively. Conclusions For elderly patients with severe coronary artery calcification, PCCT coronary angiography has a high accuracy in the diagnosis of obstructive coronary artery stenosis.

Key words: photon-counting computed tomography, coronary angiography, aged, calcified plaque, invasive coronary angiography

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