甘油三酯葡萄糖指数及其衍生指数与老年冠心病病人合并心房颤动的相关性研究

doi:10.3969/j.issn.1003-9198.2025.10.015

Abstract

Abstract: Objective To investigate the correlation of triglyceride glucose index (TyG index) and its derivative indices with atrial fibrillation (AF) in the elderly patients with coronary heart disease (CHD). Methods A retrospective analysis included 261 patients with CHD admitted to Cardiovascular Department of Xuzhou Central Hospital from October 2022 to October 2023 was conducted. All patients were divided into CHD without AF group (n=128) and CHD with AF group (n=133) according to the presence of AF during hospitalization. The clinical data and laboratory results were collected, and TyG index and TyG-BMI index were subsequently calculated. Multivariate logistic regression analysis was used to analyze the risk factors for AF in CHD patients. Receiver operating characteristic (ROC) curve analysis was used to assess the predictive value of TyG index and TyG-BMI index for AF in CHD patients. Spearman correlation coefficient was used to evaluate the correlation between TyG index, TyG-BMI index and the severity of AF. Results The levels of TyG index and TyG-BMI index in CHD with AF group were significantly higher than those in CHD without AF group (P<0.05). Multivariate logistic regression analysis showed that TyG index was an independent risk factor for AF in CHD patients (P<0.05). The areas under the ROC curve of TyG index and TyG-BMI index in predicting AF in CHD patients were 0.736 (95%CI: 0.675－0.797, P<0.05), and 0.621 (95% CI: 0.552－0.689, P<0.05), respectively. Spearman rank correlation analysis showed positive correlations between both indices and the severity of AF(r=0.337 for TyG index, r=0.202 for TyG-BMI index, both P<0.01). Conclusions TyG index is an independent risk factor for AF in CHD patients, and demonstrates predictive value for the occurrence of AF. It is positively correlated with the severity of AF. Monitoring TyG index can help identify high-risk patients with AF.

Key words: triglyceride glucose index, triglyceride glucose body mass index, aged, coronary atherosclerotic heart disease, atrial fibrillation, insulin resistance, risk factor

CLC Number:

XU Hui, LI Zhenyong, HAN Bing, DU Wei, LU Yao, DONG Qingshan. Association of triglyceride-glucose index and its derivative indices with atrial fibrillation in elderly patients with coronary heart disease[J]. Practical Geriatrics, 2025, 39(10): 1043-1047.

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Association of triglyceride-glucose index and its derivative indices with atrial fibrillation in elderly patients with coronary heart disease

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