表皮生长因子受体突变与非小细胞肺癌脑转移的相关性研究进展

doi:10.3969/j.issn.1003-9198.2025.03.020

Abstract

Abstract: Lung cancer ranks as the leading cause of cancer-related mortality among the elderly population. Brain metastases represent a significant factor contributing to the poor prognosis of the patients with lung cancer. Non-small cell lung cancer(NSCLC) is a common subtype of lung cancer.This review aims to comprehensively examine the correlation between epidermal growth factor receptor(EGFR) mutations and the occurrence of brain metastases in NSCLC patients, as well as the treatment strategies for those with EGFR-mutant NSCLC who present with brain metastases, especially the targeted therapy provided by the latest epidermal growth factor receptor tyrosine kinase inhibitors(EGFR-TKIs).

Key words: non-small cell lung cancer, brain metastases, epidermal growth factor receptor

CLC Number:

R 734.2

FANG Tingwen, ZENG Lulin, LU Kaihua. Relationship between EGFR mutation and brain metastases in non-small cell lung cancer[J]. Practical Geriatrics, 2025, 39(3): 303-307.

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Relationship between EGFR mutation and brain metastases in non-small cell lung cancer

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