睡眠障碍与老年术后认知功能障碍的双向关联研究进展

doi:10.3969/j.issn.1003-9198.2024.05.001

摘要/Abstract

摘要： 术后认知功能障碍(POCD)是老年病人麻醉和手术后常见的中枢神经系统并发症,严重影响病人的生存质量。一系列证据表明,睡眠障碍不仅是老年POCD的重要临床表现,也是其关键危险因素,睡眠障碍与老年POCD之间存在双向关系,其可能的机制包括神经炎症、氧化应激、蛋白沉积、类淋巴系统功能障碍等。本文旨在对睡眠障碍与老年POCD之间的双向关系及其机制关联的研究进展进行综述,并对睡眠障碍治疗POCD的潜在前景进行展望。

中图分类号:

陈昕露, 周艺铭, 韩雪, 顾小萍. 睡眠障碍与老年术后认知功能障碍的双向关联研究进展[J]. 实用老年医学, 2024, 38(5): 433-437.

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