≥70岁老年患者内脏脂肪面积与动脉粥样硬化性心血管疾病的相关性研究

doi:10.3969/j.issn.1003-9198.2026.08.012

摘要/Abstract

摘要： 目的探讨≥70岁老年患者内脏脂肪面积(VFA)与动脉粥样硬化性心血管疾病(ASCVD)患病的相关性。方法纳入住院≥70岁老年患者243例,采用生物电阻抗法检测人体成分,按是否患ASCVD分为ASCVD组和非ASCVD组,并比较2组基线资料的差异。采用卡方检验比较VFA四分位数组间ASCVD的患病率,采用多因素logistic回归分析探讨ASCVD的独立危险因素,采用ROC曲线分析VFA对ASCVD的预测价值。结果 ASCVD组高血压患病率、糖尿病患病率、体脂量指数(FMI)、体脂率(PBF)、VFA均高于非ASCVD组(P＜0.05);ASCVD患病率随VFA等级升高呈显著上升趋势(P<0.001);多因素logistic回归分析表明VFA(OR=1.018,95％CI:1.011~1.025,P=0.033)和糖尿病(OR=1.897,95％CI:1.012~3.559,P=0.046)是≥70岁老年患者发生ASCVD的独立危险因素。VFA预测ASCVD的ROC曲线下面积为0.710(95%CI:0.644~0.776,P<0.001)。结论 ≥70岁老年患者中,ASCVD的患病率随着VFA的增加呈增高趋势,VFA是ASCVD的独立危险因素。

关键词: 动脉粥样硬化性心血管疾病, 内脏脂肪面积, 生物电阻抗法

Abstract: Objective To explore the correlation between visceral fat area(VFA) and the prevalence of atherosclerotic cardiovascular disease (ASCVD) in the elderly patients aged ≥70 years. Methods A total of 243 elderly patients aged ≥70 years were enrolled. Body composition was measured using bioelectrical impedance analysis, and participants were divided into the ASCVD group and the non-ASCVD group based on their presence or absence of ASCVD. Differences in baseline characteristics between the two groups were analyzed. The chi-square test was employed to compare the prevalence of ASCVD among VFA quartiles; multivariate logistic regression was conducted to identify independent risk factors for ASCVD; and receiver operating characteristic (ROC) curve analysis was performed to evaluate the predictive value of VFA for ASCVD. Results The prevalence of hypertension, diabetes, body fat mass index (FMI), body fat percentage (PBF), and visceral fat area (VFA) were all higher in the ASCVD group than those in the non-ASCVD group (P<0.05). Inter-quarterile comparisons of VFA revealed a significant upward trend in ASCVD prevalence with increasing VFA levels (P<0.001). Multivariate logistic regression analysis identified VFA (OR=1.018,95%CI: 1.011-1.025, P=0.033) and diabetes (OR=1.897,95%CI: 1.012-3.559, P=0.046) as independent risk factors for ASCVD in elderly patients aged ≥70 years. The area under ROC curve of VFA in predicting ASCVD was 0.710 (95%CI: 0.644-0.776, P<0.001). Conclusions In elderly patients aged ≥70 years, ASCVD prevalence increases with higher VFA scores, confirming VFA as an independent risk factor for ASCVD.

Key words: atherosclerotic cardiovascular disease, visceral fat area, bioelectrical impedance analysis

中图分类号:

庄建芬, 单阳阳, 陈海晓, 严晓云, 徐爽, 叶佳琦, 姜英, 章颖, 羌雯慧, 张清. ≥70岁老年患者内脏脂肪面积与动脉粥样硬化性心血管疾病的相关性研究[J]. 实用老年医学, 2026, 40(8): 816-820.

ZHUANG Jianfen, SHAN Yangyang, CHEN Haixiao, YAN Xiaoyun, XU Shuang, YE Jiaqi, JIANG Ying, ZHANG Ying, QIANG Wenhui, ZHANG Qing. Association between visceral fat area and atherosclerotic cardiovascular disease in the elderly patients aged ≥70 years[J]. Practical Geriatrics, 2026, 40(8): 816-820.

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