残余胆固醇炎症指数对老年不稳定型心绞痛患者预后的预测价值

doi:10.3969/j.issn.1003-9198.2026.08.011

摘要/Abstract

摘要： 目的探讨残余胆固醇炎症指数(RCII)对老年不稳定型心绞痛(UAP)患者预后的预测价值。方法选取2024年1—12月延安大学咸阳医院收治的老年UAP患者102例为研究对象。收集所有患者基线资料,并计算残余胆固醇炎症指数(RCII)。所有患者均接受规范治疗并完成为期1年的随访,以主要不良心血管事件(MACE)发生情况作为观察终点,根据随访结果分入预后良好组(n=66)与预后不良组(n=36)。采用多因素logistic回归分析老年UAP患者预后的影响因素,采用ROC曲线评估RCII对老年UAP患者预后的预测价值。结果 102例老年UAP患者中,36例发生MACE,MACE发生率为35.29%。预后不良组年龄、全球急性冠状动脉事件注册(GRACE)评分、既往经皮冠状动脉介入治疗(PCI)史的比例及残余胆固醇(RC)、hs-CRP、RCII水平均高于预后良好组(P<0.05)。多因素logistic回归分析显示:RC(OR=2.006,95%CI:1.143~3.520)、hs-CRP(OR=2.040,95%CI:1.240~3.356)、GRACE评分(OR=2.356,95%CI:1.372~4.047)、RCII(OR=2.798,95%CI:1.738~4.505)是老年UAP患者预后的独立危险因素。ROC曲线分析显示,RC、hs-CRP及RCII预测老年UAP患者预后的AUC分别为0.792、0.804 和0.917。结论 RCII是预测老年UAP患者预后的有效新型复合指标,其预测效能优于单一的RC或炎症标志物,有望为临床风险分层与早期干预提供参考。

关键词: 不稳定型心绞痛, 老年人, 残余胆固醇炎症指数, 预后, 预测价值

Abstract: Objective To explore the predictive value of the residual cholesterol inflammatory index (RCII) for the prognosis in the elderly patients with unstable angina pectoris (UAP). Methods A total of 102 elderly UAP patients admitted to Xianyang Hospital of Yan’an University from January 2024 to December 2024 were selected. Baseline data of all patients were collected, and the value of RCII was calculated. All patients received standardized treatment and completed a 1-year follow-up, with the occurrence of major adverse cardiovascular events (MACE) as the endpoint. Based on follow-up results, the patients were divided into a good prognosis group (n=66) and an poor prognosis group (n=36). Multivariate logistic regression analysis was used to identify factors influencing the prognosis in the elderly UAP patients, and the receiver operating characteristic (ROC) curve was employed to evaluate the predictive value of RCII for prognosis. Results Among the 102 elderly UAP patients, 36 cases (35.29%) experienced MACE. The age, global registry of acute coronary events (GRACE) score, proportion of prior percutanous coronary intervention (PCI) history, levels of residual cholesterol(RC), high-sensitivity C-reactive protein (hs-CRP), and RCII were significantly higher in the poor prognosis group than those in the good prognosis group (P<0.05). Multivariate logistic regression analysis revealed that RC (OR=2.006, 95%CI: 1.143-3.520), hs-CRP (OR=2.040, 95%CI: 1.240-3.356), GRACE score (OR=2.356, 95%CI: 1.372-4.047), and RCII (OR=2.798, 95%CI: 1.738-4.505) were independent risk factors for the prognosis of elderly UAP patients. ROC curve analysis demonstrated that the AUC values of RC, hs-CRP, and RCII for predicting prognosis in elderly patients with UAP were 0.792,0.804, and 0.917, respectively. Conclusions RCII is an effective novel composite indicator for predicting the prognosis of elderly UAP patients, with superior predictive performance compared to single RC or inflammatory markers, and has potential to guide clinical risk stratification and early intervention.

Key words: unstable angina pectoris, aged, residual cholesterol inflammation index, prognosis, predictive value

中图分类号:

R 541.4

李阳波, 赵政昆. 残余胆固醇炎症指数对老年不稳定型心绞痛患者预后的预测价值[J]. 实用老年医学, 2026, 40(8): 811-815.

LI Yangbo, ZHAO Zhengkun. Predictive value of residual cholesterol inflammation index for the prognosis in elderly patients with unstable angina pectoris[J]. Practical Geriatrics, 2026, 40(8): 811-815.

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