关键词: 风险评估, 糖尿病高危足, 尿微量白蛋白/肌酐, 老年人

Abstract: Objective To analyze the correlation between diabetic foot risk score and urinary microalbumin/creatinine ratio (UMCR) in the elderly patients with type 2 diabetes mellitus (T2DM). Methods A total of 321 elderly patients with T2DM admitted to Department of Endocrinology of our hospital from January 2018 to December 2021 were enrolled in this study. According to the Gavin's foot risk factor weighted score, all patients were divided into the low risk foot group and the medium-high risk foot group. The general data and metabolic indexes of the patients were observed and compared. Multivariate Logistic regression analysis was used to analyze the influencing factors for medium-high risk foot, and receiver operating characteristic (ROC) curve was used to analyze the predictive value of UMCR for medium-high risk foot. Results There were significant differences in age, gender, living status, diabetes course, waist circumference, the levels of glycosylated hemoglobin (HbA1c), high-density lipoprotein cholesterol(HDL-C), ankle brachial index (ABI), serum uric acid(UA), UMCR, estimated glomerular filtration rate (eGFR), serum creatinine(Scr) and blood urine nitrogen(BUN) between the two groups (P<0.05). Multivariate Logistic regression analysis showed that UMCR was the risk factor for medium-high risk foot in the elderly T2DM patients(OR=1.002, 95%CI: 1.001-1.004, P<0.05). ROC curve showed that the area under the curve of UMCR in predicting medium-high risk foot was 0.739, the specificity was 78.6%, the sensitivity was 62.0% and the cut-off value was 43.23 mg/g. Conclusions UMCR is closely related to diabetic foot risk score, and has good predictive value for diabetic foot risk.

Key words: risk assessment, high risk diabetic foot, urinary microalbumin/creatinine ratio, aged