肠道菌群与老年衰弱的研究进展

doi:10.3969/j.issn.1003-9198.2021.10.018

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郭蔚, 刘艳丽, 卢霞, 王沙沙, 燕杏钰. 肠道菌群与老年衰弱的研究进展[J]. 实用老年医学, 2021, 35(10): 1072-1075.

[1] WALSTON J, HADLEY E C, FERRUCCI L, et al.Research agenda for frailty in older adults: toward a better understanding of physiology and etiology: summary from the American Geriatrics Society/National Institute on Aging Research Conference on Frailty in Older Adults[J]. J Am Geriatr Soc, 2006, 54(6):991-1001.
[2] 田鹏, 杨宁, 郝秋奎, 等. 中国老年衰弱患病率的系统评价[J]. 中国循证医学杂志, 2019, 19(6):656-664.
[3] 赵佳. 生命不同阶段肠道菌群变化及其影响因素[J]. 卫生研究, 2020, 49(1):155-159.
[4] JACKSON M A, JEFFERY I B, BEAUMONT M, et al. Signatures of early frailty in the gut microbiota[J]. Genome Med, 2016, 8(1):21.
[5] 余莉, 李红, 王思平. 基于高通量测序技术研究老年人肠道菌群结构变化[J]. 胃肠病学, 2019, 24(9):517-523.
[6] CLAESSON M J, JEFFERY I B, CONDE S, et al. Gut microbiota composition correlates with diet and health in the elderly[J]. Nature, 2012, 488(7410):178-184.
[7] SALAZAR N, VALDÉS-VARELA L, GONZÁLEZ S, et al. Nutrition and the gut microbiome in the elderly[J]. Gut Microbes, 2017, 8(2):82-97.
[8] VAN TONGEREN S P, SLAETS J P, HARMSEN H J, et al. Fecal microbiota composition and frailty[J]. Appl Environ Microbiol, 2005, 71(10):6438-6442.
[9] ROWLAND I, GIBSON G, HEINKEN A, et al. Gut microbiota functions: metabolism of nutrients and other food components[J]. Eur J Nutr, 2018, 57(1):1-24.
[10] ZAPATA H J, QUAGLIARELLO V J. The microbiota and microbiome in aging: potential implications in health and age-related diseases[J]. J Am Geriatr Soc, 2015, 63(4):776-781.
[11] RONDANELLI M, GIACOSA A, FALIVA M A, et al. Review on microbiota and effectiveness of probiotics use in older[J]. World J Clin Cases, 2015, 3(2):156-162.
[12] GAO Z, YIN J, ZHANG J, et al. Butyrate improves insulin sensitivity and increases energy expenditure in mice[J]. Diabetes, 2009, 58(7):1509-1517.
[13] DE CLERCQ N C, GROEN A K, ROMIJN J A, et al. Gut microbiota in obesity and undernutrition[J]. Adv Nutr, 2016, 7(6):1080-1089.
[14] GROSICKI G J, FIELDING R A, LUSTGARTEN M S. Gut microbiota contribute to age-related changes in skeletal muscle size, composition, and function: Biological Basis for a Gut-Muscle Axis[J]. Calcif Tissue Int, 2018, 102(4):433-442.
[15] 刘晓蕾, 岳冀蓉, 乔闰娟, 等. 肠道菌群在肌少症发病机制中的作用[J]. 实用老年医学, 2019, 33(9):840-843.
[16] 岳敏, 寇京莉, 李耘. 老年人群衰弱相关危险因素及干预措施研究进展[J]. 老年医学与保健, 2020, 26(1):148-150.
[17] 张静, 王肖枭, 周怡, 等. 肠道菌群与疾病相关性的研究进展[J]. 基础医学与临床, 2020, 40(2):243-247.
[18] KELLY J R, BORRE Y, O’ BRIEN C, et al. Transferring the blues:depression-associated gut microbiota induces neurobehavioural changes in the rat[J]. J Psychiatr Res, 2016, 82:109-118.
[19] 王鹏, 王青, 李放, 等. 潜在不适当用药与衰弱老年人不良结局的相关分析[J]. 中华老年多器官疾病杂志, 2019, 18(8):573-577.
[20] ENGELBREKTSON A, KORZENIK J R, PITTLER A, et al. Probiotics to minimize the disruption of faecal microbiota in healthy subjects undergoing antibiotic therapy[J]. J Med Microbiol, 2009, 58(Pt 5):663-670.
[21] 何海涛, 丁西平, 王金平, 等. 长期使用质子泵抑制剂对老年胃食管反流病患者肠道菌群的影响[J]. 山东医药, 2018, 58(18):47-50.
[22] 秦丽, 梁珍珍, 葛立宾, 等. 社区老年衰弱综合征的影响因素研究[J]. 中国全科医学, 2020, 23(5):598-603.
[23] MARGIOTTA E, MIRAGOLI F, CALLEGARI M L, et al. Gut microbiota composition and frailty in elderly patients with chronic kidney disease[J]. PLoS One, 2020, 15(4):e0228530.
[24] WILISON TANG W H, WANG Z N, LEVISON B S, et al. Intestinal microbial metabolism of phosphatidylcholine and cardiovascular risk[J]. N Engl J Med, 2013, 368(17):1575-1584.
[25] DUNCAN S H, FLINT H J. Probiotics and prebiotics and health in ageing populations[J]. Maturitas, 2013, 75(1):44-50.
[26] KIOUSI D E, KARAPETSAS A, KAROLIDOU K, et al. Probiotics in extraintestinal diseases: current trends and new directions[J]. Nutrients, 2019, 11(4):788.
[27] KOUTNIKOVA H, GENSER B, MONTEIRO-SEPULVEDA M, et al. Impact of bacterial probiotics on obesity, diabetes and non-alcoholic fatty liver disease related variables: a systematic review and meta-analysis of randomised controlled trials[J]. BMJ Open, 2019, 9(3):e017995.
[28] BARRETO F M, COLADO SIMÃO A N, MORIMOTO H K, et al. Beneficial effects of Lactobacillus plantarum on glycemia and homocysteine levels in postmenopausal women with metabolic syndrome[J]. Nutrition, 2014, 30(7/8):939-942.
[29] BORZABADI S, ORYAN S, EIDI A, et al. The effects of probiotic supplementation on gene expression related to inflammation, insulin and lipid in patients with Parkinson’s disease: a randomized, double-blind, placebo controlled trial[J]. Arch Iran Med, 2018, 21(7):289-295.
[30] LEI M, GUO C, WANG D, et al. The effect of probiotic Lactobacillus casei Shirota on knee osteoarthritis: a randomised double-blind, placebo-controlled clinical trial[J]. Benef Microbes, 2017, 8(5):697-703.
[31] GHOSH T S, RAMPELLI S, JEFFERY I B, et al. Mediterranean diet intervention alters thegut microbiome in older people reducing frailty and improving health status: the NU-AGE 1-year dietary intervention across five European countries[J]. Gut, 2020, 69(7):1218-1228.
[32] WANG F, YU T, HUANG G H, et al. Gut microbiota community and its assembly associated with age and diet in Chinese centenarians[J]. J Microbiol Biotechnol, 2015, 25(8):1195-1204.
[33] American Geriatrics Society 2019 Beers Criteria Update Expert Panel. American Geriatrics Society 2019 Updated AGS Beers Criteria for potentially inappropriate medication use in older adults[J]. J Am Geriatr Soc, 2019, 67(4):674-694.
[34] 温璐平, 吴海燕, 元刚. 第2版老年人不适当处方筛查工具(STOPP):2014年版[J]. 中华老年医学杂志, 2016, 35(4):452-455.
[35] 侯凯旋, 邢晓璇, 闫素英, 等. 老年人处方遗漏筛查工具第2版(中文版)[J]. 药物不良反应杂志, 2017, 19(5):375-376.
[36] 张海滨, 田雪文, 王清路, 等. 运动干预肠道菌群对代谢性疾病的改善及其机制[J]. 生理科学进展, 2019, 50(2):107-111.
[37] 都文渊, 苏书贞, 赵玉斌, 等. 八段锦改善老年人平衡能力和肠道菌群效果评价[J].预防医学, 2020, 32(4):425-428.
[38] 郑贞, 刘天宇, 申重阳, 等. 习练二十四式太极拳对人体肠内生物菌群的影响及机制探讨[J].中国病原生物学杂志, 2019, 14(11):1316-1319.

肠道菌群与老年衰弱的研究进展

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