实用老年医学 ›› 2011, Vol. 25 ›› Issue (1): 40-.

• 论著 • 上一篇    下一篇

中老年冠心病患者颈动脉超声特征研究

  

  1. 226600江苏省南通市,海安针灸推拿学校附属医院内科(张加红);210029江苏省南京市,南京医科大学第一附属医院心内科(朱军,王连生,李春坚,杨志健,朱铁兵)
  • 出版日期:2011-02-20 发布日期:2011-03-16

  • Online:2011-02-20 Published:2011-03-16

摘要:

目的通过对冠心病(CHD)患者行颈动脉彩色多普勒超声检测,探讨颈动脉血流参数与冠心病的相关性。 方法拟诊87例CHD患者,依据冠脉造影结果分为无病变组(即对照组,n=23)、1支病变组(n=21)、2支病变组(n=27)及3支病变组(n=16),≥1支病变为CHD组。全部研究对象检测空腹血糖(FBG)、三酰甘油(TG)、总胆固醇(TC)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C),超声检查颈动脉斑块数、颈总动脉内径、颈总动脉收缩期峰值血流速度(PSV)、舒张末期血流速度(EDV)、平均流速(Vmean)、搏动指数(PI)、阻力指数(RI)。结果CHD组颈动脉粥样硬化斑块数明显高于对照组,粥样硬化斑块数随着病变支数增多而增加(P<0.01)。CHD组的颈总动脉RI高于对照组(P<0.05)。年龄、收缩压与颈总动脉内径、EDV、RI密切相关。结论颈动脉斑块数及血流参数与CHD有一定关联,超声检测颈动脉对冠心病诊断、治疗有一定临床价值。

Abstract:

Study on the characteristics of carotid ultrasonography in patients with coronary heart diseaseZHANG Jia-hong. Department of Internal Medicine, the Affiliated Hospital of Haian Acupuncture and Massage College,Nantong 226600,China;ZHU Jun, WANG Lian-sheng, LI Chun-jian,YANG Zhi-jian,ZHU Tie-bing. Department of Cardiology,the First Affiliated Hospital of Nanjing Medical University, Nanjing 210029,China
【Abstract】 ObjectiveTo study the characteristics of carotid ultrasonography in patients with coronary heart disease(CHD), and to investigate the relationship between the parameters of carotid blood flow and CHD.MethodsEighty-seven subjects who underwent angiography were recruited in the study,and the subjects were categorized into 4 groups according to the characteristics of angiography: control group(n=23), single vessel lesion group(n =21),double vessel lesion group(n =27),triple vessel lesion group(n =16). All patients underwent carotid artery ultrasonography, and the carotid atherosclerosis plaque was observed simultaneously. Peak systolic velocity(PSV),end diastolic velocity(EDV),mean velocity(Vmean), pulsatility index (PI),resistance index (RI) and inner diameter of CCA were measured by color Doppler ultrasound(CDUS). Lipid profile(TG,TC,HDL-C,LDL-C)and FBG were measured by biochemistry in all patients.ResultsThe incidence rate of the carotid atherosclerotic plagues were increased with the increase of coronary artery lesion degree(P<0.01).RI in patients with CHD was significantly higher than that in control group(P<0.05). Age and systolic blood pressure were closely correlated with EVD,RI,PSV and inner diameter of CCA.ConclusionsThe number of carotid plaque and the parameter of carotid blood flow are significantly associated with CHD, and carotid ultrasound can be valuable for diagnosis and treatment of CHD.
【Key words】coronary heart disease; color Doppler ultrasound; carotid atherosclerosis plaque; parameter of carotid blood flow