实用老年医学 ›› 2010, Vol. 24 ›› Issue (1): 43-.

• 论著 • 上一篇    下一篇

老年高血压患者颈动脉内膜中层厚度与心血管危险因素关系

  

  • 出版日期:2010-02-20 发布日期:2010-03-26

Relationship between carotid artery intimamedia thickness and cardiovascular risk factors in elderly hypertensive patients

  • Online:2010-02-20 Published:2010-03-26

摘要:

目的探讨老年高血压患者颈动脉内膜中层厚度(IMT)与心血管危险因素的相关性。方法对75例老年原发性高血压患者行超声测定颈动脉IMT,同时检测患者血压、血脂、空腹血糖(FPG)、肌酐及C反应蛋白(CRP)。按照颈动脉IMT厚度分为IMT正常组和IMT增厚组,并对2组年龄、病程、血压及生化指标等进行比较。结果IMT增厚组较IMT正常组年龄较大,高血压病程较长,收缩压较高,高密度脂蛋白胆固醇(HDLC)较低, 低密度脂蛋白胆固醇(LDLC)、FPG、CRP较高;随着IMT的增厚,高LDLC、高FPG和高CRP的检出率增加。结论老年高血压患者颈动脉IMT与心血管危险因素的聚集有显著的相关性。

Abstract:

ObjectiveTo explore the relationship between carotid artery intimamedia thickness(IMT) and cardiovascular risk factors in elderly hypertensive patients.Methods205 elderly hypertensive patients were divided into two groups according to IMT, the IMT thickening group and IMT normal group. Age, course, blood pressure and related biochemical indicators were compared between two groups.ResultsThe IMT thickening group had older age and longer course than IMT normal group. The levels of blood pressure, LDLC, FPG, CRP were significantly higher and the level of HDLC in IMT thickening group was lower than those in IMT normal group.ConclusionsCarotid artery IMT is closely related to the cardiovascular risk factors in elderly hypertensive patients.