Table of Content

20 May 2024, Volume 38 Issue 5 Previous Issue    Next Issue

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Establishment and validation of a Nomogram to predict the risk of pulmonary infection in elderly patients with stroke XU Jinyan, XIA Congcong, YANG Hongmei 2024, 38 (5):  452-437.  doi: 10.3969/j.issn.1003-9198.2024.05.005 Abstract ( 77 )   PDF (1464KB) ( 603 )   Save Objective To analyze the risk factors of pulmonary infection in the elderly patients with stroke, and to establish a Nomogram to predict the risk of pulmonary infection in the elderly patients with stroke. Methods A total of 138 elderly patients with stroke admitted to our hospital from January 2020 to December 2022 were enrolled in the study. All patients were divided into infection group and non-infection group according to whether they presented with pulmonary infection. Single factor and multiple factor Logistic regression models were used to analyze the risk factors of pulmonary infection in the elderly patients with stroke,and R software was used to establish a Nomogram to predict the incidence of pulmonary infection. Receiver operating characteristic (ROC) curve was used to analyze the effectiveness of the Nomogram in predicting the incidence of pulmonary infection in the elderly patients with stroke. Results There were 32 cases (23.2%) in the infection group and 106 cases (76.8%) in the non-infection group. The proportions of the cases aged more than 70 years old, smoking history, diabetes, invasive procedures, swallowing dysfunction and disturbance of consciousness in the infection group were higher than those in the non-infection group. Logistic regression analysis showed that age, smoking history, diabetes, invasive procedures, dysphagia and disturbance of consciousness were independent influencing factors for pulmonary infection in the elderly patients with stroke (P<0.05). Hosmer-Lemeshow goodness-of-fit test showed that the Nomogram model exhibited satisfactory concordance between predicted outcome and actual outcome (P>0.05). ROC curve analysis showed that the area under the curve of the Nomogram model in predicting lung infection was 0.860 (95% CI: 0.796-0.925). Conclusions Age, smoking history, diabetes, invasive procedures, dysphagia and disturbance of consciousness are independent risk factors for pulmonary infection in the elderly patients with stroke. The Nomogram model established with the above indicators shows good predictive efficacy. References | Related Articles | Metrics

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Prevalence and risk factors of cognitive function in elderly inrural areas of Guangdong Province GUO Jinhua, SHEN Tiemei, CHEN Ling, CUI Hong, WANG Xiaoxia, HUANG Qiao, HUANG Fang, LI Yun, YANG Manqing 2024, 38 (5):  456-437.  doi: 10.3969/j.issn.1003-9198.2024.05.006 Abstract ( 89 )   PDF (983KB) ( 546 )   Save Objective To investigate the prevalence and influencing factors of cognitive impairment in the elderly in rural areas of Guangdong Province. Methods By using convenience sampling, 2819 elderly people aged ≥60 years old in rural areas of Guangdong Province from June 2021 to December 2022 were enrolled in this study. General information questionnaire and Mini-Mental State Examination (MMSE)were used for survey, and binary Logistic regression was used to analyze the influencing factors of cognitive impairment in rural elderly. Results Among the 2819 subjects, 440 cases (15.6%) presented with cognitive impairment. Logistic regression analysis showed that age and polypharmacy were the risk factors for cognitive impairment, while BMI ＞ 23.9, living with spouse and children, labor income, regular physical examination, regular participation in social activities every week and regular physical exercise every week were the protective factors for cognitive impairment. Conclusions The incidence of cognitive impairment in the elderly in rural areas of Guangdong Province is relatively high. Appropriate early screening and effective intervention measures for cognitive impairment in rural elderly should be developed to reduce or delay the occurrence of dementia. References | Related Articles | Metrics

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Status and influencing factors of symptom perception in elderly patients with heart failure LIU Lin, WU Qing, ZHANG Jing, MAO Fangying, YU Lu, REN Yiting, FANG Ting 2024, 38 (5):  461-437.  doi: 10.3969/j.issn.1003-9198.2024.05.007 Abstract ( 85 )   PDF (1016KB) ( 617 )   Save Objective To investigate the status of symptom perception in the elderly patients with heart failure, and to analyze the influencing factors of symptom perception. Methods A total of 468 elderly patients with heart failure were selected by convenience sampling from June 2021 to June 2022 in the cardiovascular department of our hospital. The clinical data within 72 hours of admission were collected. Multiple linear regression was used to analyze the independent influencing factors of symptom perception in the elderly patients with heart failure. Results The average age of 468 elderly patients with heart failure was 73.70±8.04 years, and the total symptom perception score was 43.11±8.69. Educational level, spouse, NYHA cardiac function grade, pacemaker, number of concurrent diseases, social support, health literacy and depression were the independent influencing factors of symptom perception in the elderly patients with heart failure. Conclusions The symptom perception level of the elderly patients with heart failure is at a moderate level, and it will be influenced by many factors. Medical staff should pay more attention to the symptom perception of the patients, and formulate personalized intervention measures from the aspects of demographic factors, disease factors and environmental factors. References | Related Articles | Metrics

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Clinical analysis of the plasma level of melatonin in the elderly patients with sarcopenia ZHOU Lingshan, ZHANG Haiyan, LUO Yin, AO Xiaojun, LIU Rong, YANG Yuan, QIAO Chengdong 2024, 38 (5):  465-437.  doi: 10.3969/j.issn.1003-9198.2024.05.008 Abstract ( 73 )   PDF (1148KB) ( 663 )   Save Objective To investigate the level and the clinical significance of plasma level of melatonin in the elderly patients with sarcopenia. Methods A case-control study was conducted. Forty elderly patients with sarcopenia (≥60 years old) who visited Department of Geriatrics, the First Hospital of Lanzhou University from December 2022 to May 2023 were enrolled in the sarcopenia group. Forty elderly patients without sarcopenia in the same period were enrolled in the control group with gender 1∶1 matching condition. The basic clinical data, sarcopenia-related indicators, routine laboratory indicators and plasma level of melatonin were collected and compared between the two groups. Pearson correlation analysis was used to evaluate the correlation between plasma level of melatonin and sarcopenia-related indicators. Multivariate Logistic regression analysis was performed to analyze the independent influencing factors of sarcopenia. And receiver operating characteristic (ROC) curve was used to evaluate the value of melatonin in predicting sarcopenia. Results The plasma level of melatonin in the sarcopenia group was significantly lower than that in the control group(P＜0.01). Plasma level of melatonin was positively correlated with appendicular skeletal muscle index (ASMI) (r=0.520,P＜0.01). Conditional Logistic regression analysis showed that plasma level of melatonin was an independent protective factor for sarcopenia(OR=0.807,P=0.017). ROC curve showed that the best cut-off value of plasma melatonin level in predicting sarcopenia was 3.2 ng/L, with sensitivity of 76.7%, specificity of 68.3%, and the area under the ROC curve was 0.715(P＜0.01). Conclusions The level of plasma melatonin in the elderly patients with sarcopenia is significantly decreased, which can be used as a potential biomarker for sarcopenia. References | Related Articles | Metrics

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Influence of tropical climate on blood pressure, peripheral blood microRNA-146a and Hcy in elderly patients with essential hypertension from northeast China WANG Chao, CHEN Xiaojun 2024, 38 (5):  470-437.  doi: 10.3969/j.issn.1003-9198.2024.05.009 Abstract ( 64 )   PDF (969KB) ( 605 )   Save Objective To investigate the influence of tropical climate on blood pressure, peripheral blood microRNA-146a and homocysteine (Hcy) in the elderly patients with essential hypertension from Northeast China. Methods A total of 252 elderly patients with essential hypertension who came to Sanya for winter from the three provinces in Northeast China and admitted to Sanya Central Hospital from October 2018 to January 2022 were enrolled as the study group, and 126 local elderly patients with essential hypertension in Sanya were enrolled as the control group. The blood pressure of all patients were measured and the levels of peripheral blood microRNA-146a and Hcy were detected at the time of the 1st week, the 3rd month and the 6th month in Sanya, and the control rate of hypertension and the incidence rate of adverse reactions and complications were observed and compared between the two groups. Results After 6 months of treatment, the control rate of hypertension in the study group was higher than that in the control group (P<0.05), and was higher than that after 1 week of treatment in the study group (P<0.05). The systolic and diastolic blood pressure, the levels of peripheral blood microRNA-146a and serum Hcy in the study group decreased gradually from the 1st week, the 3rd month to the 6th month (P<0.05). After 3 months and 6 months of treatment, the systolic and diastolic blood pressure, the levels of peripheral blood microRNA-146a and serum Hcy in the study group were lower than those in the control group (P<0.05). Conclusions The tropical climate can relax the smooth muscles of elderly patients with essential hypertension from Northeast China, decrease blood pressure, reduce inflammatory reactions and lower microRNA-146a and Hcy. Thus, the complications and adverse events related to hypertension can be reduced. References | Related Articles | Metrics

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Correlation between insulin-like growth factor-1 and frailty syndrome in hospitalized elderly patients KOU Xi, LIU Yonghong, DONG Wei,WANG Hua, WANG Baomei, GAO Yufang 2024, 38 (5):  474-437.  doi: 10.3969/j.issn.1003-9198.2024.05.010 Abstract ( 72 )   PDF (974KB) ( 561 )   Save Objective To investigate the correlation between insulin-like growth factor-1 (IGF-1) and frailty syndrome in the hospitalized elderly patients. Methods A total of 201 elderly patients hospitalized in Department of Geriatrics from March to August 2021 were enrolled in this study. According to frailty index (FI), all patients were divided into non-frailty group, pre-frailty group and frailty group. The clinical data such as nutritional status, living ability and comorbidities were collected and the level of IGF-1 was detected, and all parameters were compared among the three groups. The influencinig factors of frailty syndrome were analyzed. Results The proportion of non-frailty, pre-frailty and frailty in 201 cases was 7.46% (15 cases), 44.28% (89 cases) and 48.26% (97 cases), respectively. The differences in age, Barthel index, nutritional risk, types of medication, proportion of coronary heart disease and the level of IGF-1 were statistically significant among the three groups (P＜0.05).Multiple ordered Logistic regression analysis showed that the decline of Barthel index was a risk factor for frailty (OR=1.859, 95%CI:1.103-3.134), and the high level of IGF-1 was a protective factor for frailty (OR=0.984, 95%CI: 0.976-0.992). Partial correlation analysis showed that IGF-1 was negatively correlated with FI (r=-0.241, P<0.05). Conclusions The incidence of frailty is high in hospitalized elderly patients. The decrease of Barthel index is a risk factor for frailty, and the increase of IGF-1 is a protective factor for frailty. References | Related Articles | Metrics

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Impact of feed-forward control training on the risk of falls in the elderly ZHUANG Xin, ZONG Zhiying, XU Hua, ZHENG Juan, WU Jinfang, LIU Kaihang, ZHAO Jing, ZHANG Lixia 2024, 38 (5):  478-437.  doi: 10.3969/j.issn.1003-9198.2024.05.011 Abstract ( 63 )   PDF (963KB) ( 565 )   Save Objective To observe the impact of feed-forward control training on the risk of falls in the elderly. Methods Sixty elderly people who met the inclusion and exclusion criteria were randomly divided into the control group and the observation group by a random number table method, with 30 cases in each group. The control group received 8 weeks of routine fall prevention training, while the observation group received 8 weeks of feed-forward control training. Before and after 8 weeks of exercise, Berg Balance Scale (BBS), Tinetti Gait Assessment Scale (Tinetti) and Falls Efficacy Scale-International(FES-I) were assessed, and central motor conduction time (CMCT) was detected. The parameters were compared between the two groups. Results There were no statistically significant differences in the scores of BBS, Tinetti and FES-I, and CMCT between the two groups before training (P>0.05). After 8 weeks of training, the scores of BBS and Tinetti in the two groups were significantly higher than those before training (P<0.05). But the scores of BBS and Tinetti showed no statistically significant differences between the two groups (P>0.05). After 8 weeks of training, the level of CMCT was lower and the FES-I score was higher in the observation group than that before training and that in the control group (P<0.05). Conclusions Both 8-week feed-forward control training and routine fall prevention training can reduce the risk of falls in the elderly, and feed-forward control training may have an effect in improving confidence in preventing falls and central nervous system conduction velocity in the elderly. References | Related Articles | Metrics

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Correlation between serum osteocalcin and muscle mass in overweight elderly male WANG Qing, DENG Hui 2024, 38 (5):  482-437.  doi: 10.3969/j.issn.1003-9198.2024.05.012 Abstract ( 60 )   PDF (971KB) ( 425 )   Save Objective To analyze the association between serum osteocalcin and muscle mass in overweight elderly male. Methods A total of 167 overweight elderly male patients admitted to Department of Geriatrics, Nanjing Drum Towel Hospital from January 2020 to December 2022 were enrolled in this study. The subjects were classified into low osteocalcin group and normal osteocalcin group based on the serum level of osteocalcin.The relationship between the serum level of osteocalcin and lumbar and hip muscle masses was analyzed. Multiple linear regression analysis was used to analyze the influencing factors of muscle mass. Results Significant differences were observed in age and the levels of glycosylated hemoglobin A1c (HbA1c), type Ⅰ collagen cross-linked C-terminal peptide (CTX), type Ⅰ procollagen amino terminal peptide (P1NP), 25-hydroxy vitamin D, waist muscle mass and hip muscle mass between the two groups (all P<0.05). The lumbar muscle mass and hip muscle mass were positively correlated with the levels of osteocalcin, CTX and P1NP(r=0.204-0.322, all P<0.05), and negatively correlated with age, BMI and abdominal circumference (r=-0.282--0.187, all P<0.05). Multiple linear regression analysis showed that age and abdominal circumference were the independent influencing factors of hip muscle mass (β=-0.081 and -0.127, both P<0.05), while age, abdominal circumference and osteocalcin were the independent influencing factors of lumbar muscle mass (β=-0.201,-0.136, 0.187, all P<0.05). Conclusions There are positive correlations between lumbar and hip muscle masses and serum level of osteocalcin in overweight elderly male patients. Furthermore, osteocalcin is an independent influencing factor of lumbar muscle mass. References | Related Articles | Metrics

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Relationship between serum thyrotropin and risk of cognitive impairment in elderly with normalthyroid function and subclinical hypothyroidism WEI qian, CAI Yingyuan, WANG Shan,TAN Fuyun, LU Xiaowei 2024, 38 (5):  486-437.  doi: 10.3969/j.issn.1003-9198.2024.05.013 Abstract ( 64 )   PDF (1155KB) ( 698 )   Save Objective To investigate the association between serum thyroid-stimulating hormone (TSH) level and cognitive impairment (CI) in the elderly with normal thyroid function or subclinical hypothyroidism (SCH). Methods A total of 292 elderly patients with normal thyroid function or SCH in Department of Geriatrics, Jiangsu Province Hospital from Jul 2016 to Dec 2018 were retrospectively enrolled in this study. Montreal Cognitive Assessment(MoCA)was used to measure the cognitive function. The demographic and clinical data were collected.The restricted cubic spline model and multivariate Logistic regression model were used to explore the correlation between serum TSH concentration and the risk of CI and the dose-response relationship, and subgroup analyses were performed to evaluate the influence of multiple factors on CI. Results The CI group (MoCA < 26, n=230) included 30 cases of SCH, while the non-CI group (MoCA ≥ 26, n=62) had no SCH case, showing a significant difference in SCH prevalence (P<0.001). No significant difference in TSH level were observed between the two groups (P>0.05).Restricted cubic spline showed that the dose-response relationship between TSH and the risk of CI was U-shaped (P=0.047).The SCH patients were set as the SCH group, and those with normal TSH level were divided into normal low group (0.41-1.48 mIU/L), normal middle group (1.49-2.51 mIU/L) and normal high group (2.52-4.50 mIU/L) according to tertile of TSH levels. After adjustment for all confounders, the odds ratios for CI were 0.37(95%CI: 0.16-0.80) and 7.72(95%CI: 2.15-51.02) for the normal high group and SCH group, respectively, compared with the normal low group.Subgroup analysis showed that the serum TSH level was significantly negatively associated with the risk of CI in male subjects and subjects aged 75 years and over (P<0.05). Conclusions Increased serum TSH levels within the normal range may reduce the risk of cognitive impairment. SCH is an independent risk factor for cognitive impairment in the elderly. References | Related Articles | Metrics

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Effects of HbA1c level on cardiac structure and function in elderly patients with type 2 diabetes mellitus and chronic heart failure LIU Qianhui, YAO Zijun, HE Yuli, XU Yunfan, WU Jun 2024, 38 (5):  491-437.  doi: 10.3969/j.issn.1003-9198.2024.05.014 Abstract ( 63 )   PDF (1023KB) ( 752 )   Save Objective To analyze the relationship of glycosylated hemoglobin (HbA1c) level with cardiac structure and function in elderly patients with chronic heart failure and type 2 diabetes (T2DM). Methods A total of 210 elderly patients with chronic heart failure (NYHA gradeⅡ-Ⅳ)combined with T2DM were divided into two groups based on the mean value of HbA1c≤7% or ＞7%.The levels of blood lipid, cardiac structure and function were detected and compared between the two groups.And the correlation of HbA1c with blood lipid, cardiac structure and function were analyzed by Spearman correlation analysis. Results HbA1c ≤ 7% group and HbA1c>7% group showed statistical differences in interventricular septal thickness (IVS), left ventricular posterior wall thickness(LVPW), left ventricular fractional shortening rate (Fs), left ventricular ejection fraction(LVEF), total cholesterol (TC), and low-density lipoprotein cholesterol (LDL-C) (P<0.05). Spearman correlation analysis showed that HbA1c level was positively correlated with the levels of IVS, LVPW, TC and LDL-C(r=0.138, 0.152, 0.289, 0.290, P<0.05), and negatively correlated with the level of LVEF(r=-0.196, P<0.05). Conclusions The elderly patients with T2DM and chronic heart failure whose HbA1c level is higher than 7% have higher levels of TC and LDL-C. Controlling the level of HbA1c below 7% can effectively delay the decline of cardiac structure and function. References | Related Articles | Metrics

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Effect of glucose metabolic disorders on serum levels of activin-A LIU Tongjun, ZHAO Yajie, HU Jieling, HU Yang, LIANG Wei 2024, 38 (5):  495-437.  doi: 10.3969/j.issn.1003-9198.2024.05.015 Abstract ( 68 )   PDF (995KB) ( 460 )   Save Objective To explore the expression of serum ACT-A in the elderly with different glucose staus. Methods A total of 293 stable patients who underwent physical examination in the VIP department of Ruijin Hospital from July 2022 to February 2023 were enrolled. The serum ACT-A level was detected, and the expression differences of ACT-A in the patients with different clinical characteristics and the influencing factors in the patients with different glucose status were analyzed. Results The level of ACT-A increased with age and the progression of diabetes (P<0.01). The level of ACT-A was higher in elderly diabetic patients with HbA1c≥7%, renal insufficiency, hypertension history, pulse pressure>55 mmHg and pulse pressure index>0.45. In diabetes population, Pearson correlation analysis and linear regression confirmed that the level of ACT-A was positively correlated with age, HbA1c, and HOMA-IR(B=20.996, 33.391, 57.482, P<0.05), and negatively correlated with the level of fasting insulin(B=-17.794, P<0.05). Conclusions The level of ACT-A is positively correlated with age. The level of ACT-A can be increased in the patients with prediabetes, and further increased in the patients with diabetes. Age, HbA1c, HOMA-IR and fasting insulin are independently associated with ACT-A level in diabetic patients. References | Related Articles | Metrics

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Risk factors and prognosis of new continuous complete left bundle branch block in elderly patients undergoing transcatheter aortic valve replacement DU Zhaona, JIANG Wenbo, MOU Junyu, YU Chengyun, XIA Wei 2024, 38 (5):  500-437.  doi: 10.3969/j.issn.1003-9198.2024.05.016 Abstract ( 65 )   PDF (995KB) ( 484 )   Save Objective To analyze the risk factors associated with new-onset persistent complete left bundle branch block (cLBBB) in the elderly patients with aortic stenosis undergoing transcatheter aortic valve replacement (TAVR) and the impact of cLBBB on short-term prognosis. Methods The clinical data of 78 elderly patients who underwent TAVR via femoral artery at the Heart Center of Qingdao Municipal Hospital from January 2019 to August 2022 were retrospectively analyzed, and the patients were divided into the new-onset persistent cLBBB group (n=26 ) and the non-LBBB group (n=52) according to whether cLBBB occurred after TAVR during the hospitalization. The baseline data, the levels of biochemical indexes, CT and cardiac ultrasonography imaging, valve-related and surgery-related data and the prognosis during 6 months of follow-up were compared between the two groups. A multiple Logistic regression model was used to analyze the risk factors of new-onset persistent cLBBB after TAVR. Results Of the 78 patients, 26 patients (33.3%) presented with persistent cLBBB after TAVR. Logistic regression analysis showed that preoperative presence of incomplete LBBB (OR=7.609,95%CI:1.051-55.066), oversize rate of implanted valve ≥17.25% (OR=1.096,95%CI:1.017-1.181) and valve implantation depth≥4.96 mm at sinus-free side (OR=3.633,95%CI:1.363-9.686) were the independent risk factors for new-onset persistent cLBBB after TAVR. During 6 months of follow-up, the new persistent cLBBB group had a higher rate of heart failure rehospitalization (16.0% vs 1.9%, P=0.02) compared to the non-LBBB group. Conclusions Preoperative incomplete LBBB, implantation of large-size valves and deep implantation of coronary sinusless lateral valves are the risk factors of persistent cLBBB after TAVR, and the patients with new-onset cLBBB have a higher risk of rehospitalization due to heart failure. References | Related Articles | Metrics

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Relationship of sleep spindles with depression, anxiety with cognitive function in elderly patients with first episode of depression WANG Jinpeng, ZHANG Shun, ZHANG Xiaojuan, WANG Liping, MA Wenyou 2024, 38 (5):  505-437.  doi: 10.3969/j.issn.1003-9198.2024.05.017 Abstract ( 68 )   PDF (962KB) ( 566 )   Save Objective To analyze the relationship of sleep spindles (SS) with depression, anxiety and cognitive function in the elderly patients with first episode of depression. Methods A total of 40 patients with the first episode of geriatric depression admitted to our hospital from January 2021 to January 2022 were retrospectively selected as the elderly group, while 40 young and middle-aged patients with depression were enrolled as the young and middle-aged group, and 40 healthy elderly receiving physical examination were enrolled as the healthy group. The deletional rate and abnormal rate of SS, and the scores of Hamilton Anxiety Scale (HAMA), Hamilton Depression Scale (HAMD) -17 and Montreal Cognitive Function Assessment Scale (MoCA) were compared among the three groups. The deletional rate and abnormal rate of SS were also compared between the different gender and different cognitive function subgroups. Results The SS deletion rate (57.50%) and abnormal rate (62.50%) in the elderly group were higher than those in the young and middle-aged group (32.50%, 2.50%) and the healthy group (35.00%, 2.50%) (P<0.05). HAMA score and HAMD-17 score showed no significant differences between the elderly group and the young and middle-aged group (P>0.05), but they were higher than those in the healthy group (P<0.05). The MoCA score in the elderly group was lowest, followed by the young and middle-aged group and the healthy group (P<0.05). There was no significant difference in the deletional rate of SS between the male and female elderly patients (P>0.05). The SS deletional rate in the young and middle-aged female patients was significantly lower than that in the young and middle-aged male patients and the elderly female patients (P<0.05). The deletional rate and abnormal rate of SS in the patients with cognitive dysfunction were higher than those without cognitive dysfunction in the elderly group (P<0.05). Conclusions The deletion rate and abnormal rate of SS are relatively high in the elderly patients with first episode of depression, and SS is related to cognitive function. References | Related Articles | Metrics

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Effect of trans-theoretical model on fatigue and psychological health in elderly patients with epilepsy TANG Yue, ZHU Jianying, LIU Weiguo, XIANG Yang, LI Xuefen 2024, 38 (5):  533-437.  doi: 10.3969/j.issn.1003-9198.2024.05.024 Abstract ( 75 )   PDF (955KB) ( 610 )   Save Objective To explore the influences of nursing intervention by a trans-theoretical model (TTM) on the psychological health and fatigue status in the elderly patients with epilepsy. Methods A total of 95 elderly inpatients with epilepsy were enrolled from January 2021 to March 2023. Personalized TTM care was performed on all subjects for 3 months. Before and after the intervention, the self-rating anxiety scale (SAS), self-rating depression scale (SDS), revised piper fatigue scale (RPFS), the stage variation and span of TTM, the knowledge of antiepilepsy drugs and the mastery of self-rescue were evaluated and compared. Results After 3 months of behavioral nursing intervention, the scores of SAS, SDS, RPFS, and the stage variation, span of TTM and the mastery of self-rescue in the elderly patients with epilepsy were significantly improved (P<0.05). Conclusions The nursing intervention based on TTM can effectively improve the behavior of the elderly patients with epilepsy, alleviate their anxiety and depression, and relieve fatigue. References | Related Articles | Metrics

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Application of humanistic care in elderly patients with amyotrophic lateral sclerosis XIE Zhaomin, LI Xuefen, ZHU Jianying, YU Mengting, LIU Weiguo, YIN Junxiong, LI Yunyi 2024, 38 (5):  537-540.  doi: 10.3969/j.issn.1003-9198.2024.05.025 Abstract ( 67 )   PDF (962KB) ( 782 )   Save Objective To investigate the effect of humanistic care-based nursing in the elderly patients with amyotrophic lateral sclerosis. Methods A total of 67 elderly patients with amyotrophic lateral sclerosis admitted to Department of Neurology,Nanjing brain Hospital from February 2021 to March 2023 were enrolled by convenient sampling. All patients’ feelings of care, self-efficacy, emotional state, and quality of life were assessed and compared before and after the application of humanistic care-based nursing. Results After the application of humanistic care-based nursing, the scores of the Care Behavior Inventory (CBI),the General Self-Efficacy Scale (GSES) and Short Form-36 Health Survey (SF-36) were significantly higher, and the scores of each subscale of the State-Trait Anxiety Inventory (STAI) were lower than those before nursing intervention(P＜0.05).The patients’ medication adherence and satisfaction with nursing care were significantly improved after the application of humanistic care-based nursing (P<0.05). Conclusions The application of humanistic care-based nursing in the elderly patients with amyotrophic lateral sclerosis can enhance the patients’ sense of care, improve self-efficacy, emotional state, treatment compliance and nursing satisfaction, and further improve their quality of life. References | Related Articles | Metrics