[1] 国务院第七次全国人口普查领导小组办公室编. 2020 年第七次全国人口普查主要数据[Z]. 中国统计出版社有限公司. 2021.
[2] YU Z, CHEN Y, XIA Q, et al. Identification of status quo and association rules for chronic comorbidity among Chinese middle-aged and older adults rural residents[J]. Front Public Health, 2023, 11: 1186248.
[3] MAESO-DÍAZ R, GRACIA-SANCHO J. Aging and chronic liver disease[J]. Semin Liver Dis, 2020, 40(4): 373-84.
[4] MOHAMAD KAMAL N S, SAFUAN S, SHAMSUDDIN S, et al. Aging of the cells: insight into cellular senescence and detection methods[J]. Eur J Cell Biol, 2020, 99(6): 151108.
[5] BELLANTI F, VENDEMIALE G. The aging liver: redox biology and liver regeneration[J]. Antioxid Redox Signal, 2021, 35(10): 832-847.
[6] TAJIRI K, SHIMIZU Y. Liver physiology and liver diseases in the elderly[J]. World J Gastroenterol, 2013, 19(46): 8459-8467.
[7] WYNNE H A, COPE L H, MUTCH E, et al. The effect of age upon liver volume and apparent liver blood flow in healthy man[J]. Hepatology, 1989, 9(2): 297-301.
[8] HU S J, JIANG S S, ZHANG J, et al. Effects of apoptosis on liver aging[J]. World J Clin Cases, 2019, 7(6): 691-704.
[9] TIETZ N W, SHUEY D F, WEKSTEIN D R. Laboratory values in fit aging individuals--sexagenarians through centenarians[J]. Clin Chem, 1992, 38(6): 1167-1185.
[10] DONG M H, BETTENCOURT R, BARRETT-CONNOR E, et al. Alanine aminotransferase decreases with age: the Rancho Bernardo Study[J]. PLoS One, 2010, 5(12): e14254.
[11] SOTANIEMI E A, ARRANTO A J, PELKONEN O, et al. Age and cytochrome P450-linked drug metabolism in humans: an analysis of 226 subjects with equal histopathologic conditions[J]. Clin Pharmacol Ther, 1997, 61(3): 331-339.
[12] SAWADA N. Hepatocytes from old rats retain responsiveness of C-myc expression to EGF in primary culture but do not enter S phase[J]. Exp Cell Res, 1989, 181(2): 584-588.
[13] IAKOVA P, AWAD S S, TIMCHENKO N A. Aging reduces proliferative capacities of liver by switching pathways of C/EBPalpha growth arrest[J]. Cell, 2003, 113(4): 495-506.
[14] TAKUBO K, NAKAMURA K, IZUMIYAMA N, et al. Telomere shortening with aging in human liver[J]. J Gerontol A Biol Sci Med Sci, 2000, 55(11): B533-536.
[15] PINTO C, NINFOLE E, GAGGIANO L, et al. Aging and the biological response to liver injury[J]. Semin Liver Dis, 2020, 40(3): 225-232.
[16] XU F, HUA C, TAUTENHAHN H M, et al. The role of autophagy for the regeneration of the aging liver[J]. Int J Mol Sci, 2020, 21(10):3606.
[17] FULOP T, LARBI A, KOTB R, et al. Aging, immunity, and cancer[J]. Discov Med, 2011, 11(61): 537-550.
[18] ADHIKARY S, ESMEETA A, DEY A, et al. Impacts of gut microbiota alteration on age-related chronic liver diseases[J]. Dig Liver Dis, 2024,56(1):112-122.
[19] KALTOFT K. Cytokine-driven immortalization of in vitro activated human T lymphocytes. CD28 expression correlates inversely with cell population doublings[J]. Exp Clin Immunogenet, 1998, 15(2): 84-89.
[20] FRASCA D, DIAZ A, ROMERO M, et al. Age effects on B cells and humoral immunity in humans[J]. Ageing Res Rev, 2011, 10(3): 330-335.
[21] REN R, HE Y, DING D, et al. Aging exaggerates acute-on-chronic alcohol-induced liver injury in mice and humans by inhibiting neutrophilic sirtuin 1-C/EBPα-miRNA-223 axis[J]. Hepatology, 2022, 75(3): 646-660.
[22] ESLAM M, GEORGE J. Reply to: Correspondence on "a new definition for metabolic associated fatty liver disease: an international expert consensus statement": MAFLD: moving from a concept to practice[J]. J Hepatol, 2020, 73(5): 1268-1269.
[23] NOUREDDIN M, YATES K P, VAUGHN I A, et al. Clinical and histological determinants of nonalcoholic steatohepatitis and advanced fibrosis in elderly patients[J]. Hepatology, 2013, 58(5): 1644-1654.
[24] LUCENA M I, SANABRIA J, GARCÍA-CORTES M, et al. Drug-induced liver injury in older people[J]. Lancet Gastroenterol Hepatol, 2020, 5(9): 862-874.
[25] 王宝恩.肝脏病学[M].2版. 北京: 科学出版社, 2022:751.
[26] PINTO C, NINFOLE E, BENEDETTI A, et al. Aging-related molecular pathways in chronic cholestatic conditions[J]. Front Med:Lausanne, 2019, 6: 332.
[27] ROSSIELLO F, JURK D, PASSOS J F, et al. Telomere dysfunction in ageing and age-related diseases[J]. Nat Cell Biol, 2022, 24(2): 135-147.
[28] RADONJIĆ T, DUKIĆ M, JOVANOVIĆ I, et al. Aging of liver in its different diseases[J]. Int J Mol Sci, 2022, 23(21):13085. |
