听力障碍与阿尔茨海默病相关性的Meta分析

doi:10.3969/j.issn.1003-9198.2023.09.013

Abstract

Abstract: Objective To evaluate the association between hearing impairment and Alzheimer's disease. Methods The studies on the correlation between hearing impairment and Alzheimer's disease in PubMed, Web of Science, EmBase, Cochrane Library, China National Knowledge Infrastructure (CNKI), Wanfang Database, VIP and SinoMed were retrievaled by computer, and the retrieval time was from database establishment to March 28th, 2022. Review Manager 5.4 software was used for Meta-analysis. The combined risk ratio (RR) and 95% confidence interval (CI) of the included literatures were calculated,and sensitivity analysis and funnel plot bias test were carried out. Results Finally, six English literatures were enrolled. The results of Meta-analysis showed that the combined RR value of Alzheimer's disease in the patients with hearing impairment was 3.00 (95% CI: 1.58-5.70,P=0.0008). Conclusions There is a correlation between hearing impairment and Alzheimer's disease. The risk of Alzheimer's disease in the patients with hearing impairment is significantly increased.For the people presenting with hearing impairment, early intervention measures should be taken to slow down the cognitive decline.

Key words: hearing impairment, Alzheimer's disease, Meta-analysis

CLC Number:

R 749.16

WANG Min, GUO Wen-jun, TANG Zhong-quan, ZHAO Xiao-min, OU Ting, LI Yun-tao. Association between hearing impairment and Alzheimer's disease: a Meta-analysis[J]. Practical Geriatrics, 2023, 37(9): 915-919.

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Association between hearing impairment and Alzheimer's disease: a Meta-analysis

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