老年人群视网膜动脉硬化与全身因素的相关性研究

doi:10.3969/j.issn.1003-9198.2025.11.009

摘要/Abstract

摘要： 目的探究老年人群视网膜动脉硬化(RA)与全身因素的相关性。方法回顾性分析2022年10月至2024年9月于江苏省省级机关医院健康管理中心体检的2 107例 ≥60岁老年人的资料,其中891例RA者为RA组,1 216例无RA者为对照组。收集2组性别、年龄、血压、BMI、腰臀比(WHR)、FBG、TG、TC、HDL-C、LDL-C、肌酐(Cr)、尿素、UA及既往高血压、糖尿病史,吸烟、饮酒史等全身因素数据,采用SPSS 26.0 对RA与全身因素进行单因素筛查以及多因素logistic回归分析。结果 RA组年龄、收缩压、舒张压、FPG、TG、Cr、WHR以及既往高血压、糖尿病史比例,超重、肥胖的患病率较对照组高(均P<0.05),TC、HDL-C较对照组低,差异均有统计学意义(均P<0.05)。多因素logistic回归分析显示,年龄(OR=1.05)、WHR(OR=6.21)、高血压史(OR=2.28)为RA的独立危险因素(均P<0.05)。结论年龄、WHR、既往高血压史是老年人群RA的主要危险因素,早期识别和积极管理可降低视网膜血管疾病风险。

关键词: 老年人, 视网膜动脉硬化, 全身因素, 相关性

Abstract: Objective To investigate the correlation between retinal arteriosclerosis (RA) and systemic factors in the elderly population. Methods A retrospective analysis was conducted on 2 107 elderly participants (≥60 years) who underwent health examinations at Jiangsu Province Official Hospital from October 2022 to September 2024. Among them, 891 individuals with RA were assigned to the RA group, and 1 216 subjects without RA served as the control group. Systemic factors were collected, including gender, age, blood pressure, body mass index (BMI), waist to hip ratio(WHR), fasting plasma glucose(FPG), triglycerides(TG), total cholesterol(TC), high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), creatinine(Cr), Urea, uric acid(UA), hypertension, diabetes, smoking status, alcohol consumption. Univariate screening followed by multivariate logistic regression analysis was conducted using SPSS 26.0 to identify systemic factors associated with RA. Results The RA group showed significantly higher values than the control group in age, systolic and diastolic blood pressure, FPG, TG, Cr, WHR, as well as the prevalence of previous history of hypertension, diabetes and overweight, obesity (all P<0.05). The levels of TC and HDL-C levels were lower in the RA group than those in the control group (P<0.05). Multivariate logistic regression revealed age (OR=1.05), WHR (OR=6.21), and hypertension history (OR=2.28) as independent risk factors for RA (all P<0.05). Conclusions Age, WHR, and hypertension history are major risk factors for RA in the elderly population. Early identification and active management of these factors may reduce the risk of retinal vascular diseases.

Key words: aged, retinal arteriosclerosis, systemic factor, correlation

中图分类号:

R 774.1

徐森, 周文婧, 洪伟, 王颖, 潘安娜, 陈志强. 老年人群视网膜动脉硬化与全身因素的相关性研究[J]. 实用老年医学, 2025, 39(11): 1116-1120.

XU Sen, ZHOU Wenjing, HONG Wei, WANG Ying, PAN Anna, CHEN Zhiqiang. Correlation between retinal arteriosclerosis and systemic factors in elderly population[J]. Practical Geriatrics, 2025, 39(11): 1116-1120.

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