关键词: 静脉血栓栓塞症, Padua评分, 高龄, 危险性评估

Abstract: Objective To assess the predictive value of Padua score for venous thromboembolism(VTE) in the elderly inpatients. Methods A retrospective analysis was performed and 150 elderly inpatients in Department of General Practice of Hangzhou Third People's Hospital from January 2018 to June 2021 were included. All of them underwent CT pulmonary angiography or venous ultrasound of both upper(lower)limbs, and were divided into VTE group and non-VTE group. The baseline data including age, gender, underlying disease, Padua score, D-dimer, mean platelet volume(MPV), albumin were collected and compared between the two groups. Multivariate Logistic regression was used to analyze the risk factors of VTE. Receiver operating characteristic (ROC) curve analysis was carried out to assess the predictive value of Padua score. Results There were statistically significant differences in Padua score, age, hypertension, acute infection, D-dimer, MPV and albumin between the two groups. Multivariate Logistic regression analysis showed that aged ≥85 years old was the independent risk factor for VTE of elderly inpatients. The area under the curve (AUC) of Padua score to predict the incidence of VTE was 0.631, with a cut-off value of 4.5, and the Youden index was 0.36. Conclusions The predictive value of Padua score for VTE in elderly inpatients is limited.

Key words: venous thromboembolism, Padua score, aged, risk assessment