实用老年医学 ›› 2025, Vol. 39 ›› Issue (5): 444-449.doi: 10.3969/j.issn.1003-9198.2025.05.003

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老年重症病人能量和蛋白质供给目标研究进展

江洁, 周丹丹, 朱宝华   

  1. 210008 江苏省南京市,南京市中心医院(南京市市级机关医院,南京市老年病医院)重症医学科(江洁,朱宝华); 210028 江苏省南京市,南京中医药大学附属中西医结合医院急重症医学科(周丹丹)
  • 收稿日期:2025-03-24 出版日期:2025-05-20 发布日期:2025-05-20
  • 通讯作者: 朱宝华,Email:13512538600@139.com
  • 作者简介:朱宝华 主任医师

Advances in energy and protein treatment goals for elderly critically ill patients

JIANG Jie, ZHOU Dandan, ZHU Baohua   

  1. Department of ICU, Nanjing Central Hospital, Nanjing 210008, China (JIANG Jie, ZHU Baohua); Department of ICU, Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing 210028, China (ZHOU Dandan)
  • Received:2025-03-24 Online:2025-05-20 Published:2025-05-20
  • Contact: ZHU Baohua, Email: 13512538600@139.com

摘要: 随着人口老龄化加剧,老年重症病人数量日益增多,其营养支持问题亟待关注。本文深入探讨老年重症病人能量和蛋白质代谢特点,剖析临床营养目标设定,强调个体化营养治疗的重要性。研究发现,老年重症病人能量代谢异质性明显,蛋白质代谢存在“合成抵抗”,传统营养支持策略需优化。基于近年研究及指南,提出能量与蛋白质供给应依据病人状况精准调整。未来,个体化、精准化、分阶段及多学科协作的营养治疗模式将成为主流,有望为老年重症病人带来更好的临床结局,减轻社会公共卫生负担。

关键词: 老年人, 重症, 能量代谢, 蛋白质代谢, 营养支持

Abstract: With the increasing aging population, the number of elderly critically ill patients is rising, making nutritional support issues urgent. This review provides an in-depth analysis of the metabolic characteristics of energy and protein metabolism in the elderly critically ill patients, explores the establishment of clinical nutritional goals, and emphasizes the importance of individualized nutritional therapy. Research has demonstrated significant heterogeneity in energy metabolism among the elderly critically ill patients, along with the phenomenon of “anabolic resistance” in protein metabolism, highlighting the need for optimization of traditional nutritional support strategies. Based on recent studies and clinical guidelines, this review emphasizes that energy and protein intake should be precisely adjusted according to the patient’s condition. In the future, individualized, precision-based, phased, and multidisciplinary collaborative nutritional treatment strategies will become the mainstream approach, promising better clinical outcomes for the elderly critically ill patients and reducing the burden on public healthcare systems.

Key words: aged, critically illness, energy metabolism, protein metabolism, nutritional support

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