脑深髓静脉视觉评分的影响因素分析及其与脑小血管病总负荷的相关性

doi:10.3969/j.issn.1003-9198.2023.08.014

摘要/Abstract

摘要： 目的探讨脑深髓静脉(DMV)视觉评分的影响因素及其与脑小血管病(CSVD)总负荷的相关性。方法选取唐山市工人医院180例CSVD病人为研究对象,DMV视觉评分与CSVD总负荷的相关性采用Spearman相关分析,对DMV视觉评分的相关因素进行多因素有序Logistic回归分析。结果 DMV视觉评分与CSVD总负荷呈正相关(r＝0.760,P＜0.001);有序Logistic回归分析结果显示,年龄(OR=1.280, 95%CI:1.208~1.355, P＜0.001)、推测为血管源性腔隙灶(LPVO)(OR=4.679, 95%CI:2.234~9.800, P＜0.001)、脑微出血(CMB)(OR=3.605, 95%CI:1.855~7.003, P＜0.001)、血管周围间隙(PVS)(OR=2.588, 95%CI:1.179~5.682, P=0.018 )、脑白质高信号(WMH)(OR=7.440, 95%CI:3.279~16.880, P＜0.001 )是DMV视觉评分的独立影响因素。结论 DMV视觉评分与CSVD总负荷存在强关联,DMV可视度越差,CSVD全脑损伤越严重。年龄、LPVO、CMB、PVS、WMH是DMV视觉评分的独立影响因素。

关键词: 深髓静脉视觉评分, 脑小血管病总负荷, 影响因素

Abstract: Objective To explore the influencing factors of deep medullary vein(DMV) visual score and the correlation between total burden of cerebral small vessel disease(CSVD) and DMV visual score. Methods A total of 180 CSVD patients admitted to Tangshan Workers' Hospital were enrolled in this study. The correlation between DMV visual score and the total burden of CSVD was analyzed by Spearman correlation analysis. Multivariate ordinal Logistic regression analysis was performed to analyze the relevant factors of DMV visual score. Results DMV visual score was positively correlated with the total burden of CSVD(r=0.760, P<0.001). Multivariate ordinal Logistic regression analysis showed that age(OR=1.280, 95%CI: 1.208-1.355, P<0.001), lacune of presumed vascular origin(LPVO)(OR=4.679, 95% CI: 2.234-9.800, P<0.001), cerebral microbleed(CMB)(OR=3.605, 95%CI: 1.855-7.003, P<0.001), perivascular space(PVS)(OR=2.588, 95%CI: 1.179-5.682, P=0.018), and white matter hyperintensity(WMH)(OR=7.440, 95%CI: 3.279-16.880, P<0.001) were the independent influencing factors of DMV visual scores. Conclusions There is a strong correlation between DMV visual score and the total burden of CSVD, and the worse the visibility of DMV is, the more severe the overall brain damage of CSVD is. Age, LPVO, CMB, PVS, and WMH show significant influence on DMV visual score.

Key words: deep medullary vein visual score, total burden of cerebrovascular disease, influencing factor

中图分类号:

R 743

姚贺玲, 王余, 王欣, 冯丽娜, 杨越清, 赵彤彤, 韩德昌, 马梦华. 脑深髓静脉视觉评分的影响因素分析及其与脑小血管病总负荷的相关性[J]. 实用老年医学, 2023, 37(8): 811-814.

YAO He-ling, WANG Yu, WANG Xin, FENG Li-na, YANG Yue-qing, ZHAO Tong-tong, HAN De-chang, MA Meng-hua. Analysis of influencing factors of deep medullary vein visual score and its correlation with total burden of cerebral small vessel disease[J]. Practical Geriatrics, 2023, 37(8): 811-814.

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