老年患者S型室间隔与左心室舒张功能的相关性研究

doi:10.3969/j.issn.1003-9198.2026.10.010

摘要/Abstract

摘要： 目的探讨老年患者S型室间隔与左心室舒张功能的相关性。方法采用病例对照研究,纳入2020年1月至2026年1月于南京医科大学附属老年医院行超声心动图检查诊断为S型室间隔者36例(S型室间隔组),并按年龄、性别匹配,纳入无S型室间隔者98例为对照组。比较2组临床及超声心动图资料,采用多因素logistic回归、多元线性回归及有序logistic回归分析S型室间隔与左心室舒张功能及其严重度分级的关联。结果 S型室间隔组高血压及左心室舒张功能减退比例、左心房内径和E/e′高于对照组,E/A及间隔e′低于对照组(均P＜0.05)。多因素logistic回归、多元线性回归及有序logistic回归分析均显示,S型室间隔与左心室舒张功能减退及其严重度分级独立相关(P＜0.05)。结论老年患者S型室间隔与左心室舒张功能减退独立相关,超声心动图检出S型室间隔可作为左心室舒张功能不全的影像学线索,对此类患者应常规完善舒张功能的定量评估。

关键词: S型室间隔, 左心室舒张功能, 老年人

Abstract: Objective To investigate the association between sigmoid septum(SS) and left ventricular(LV) diastolic function in elderly patients. Methods In this case-control study, 134 elderly patients who underwent echocardiography at Geriatric Hospital of Nanjing Medical University from January 2020 to January 2026 were enrolled, including 36 patients with SS(SS group) and 98 age-and sex-matched patients without SS(control group). Clinical characteristics and echocardiographic parameters were compared between the two groups. Multiple logistic regression, multiple linear regression and ordinal logistic regression analyses were performed to assess the association between SS and LV diastolic dysfunction as well as its severity grading. Results Compared with the control group, the SS group had a higher prevalence of hypertension and LV diastolic dysfunction, larger left atrial diameter and higher E/e′ ratio, and lower E/A ratio and septal e′ velocity(all P<0.05). Multivariate logistic regression, multiple linear regression and ordinal logistic regression consistently showed that SS was independently associated with LV diastolic dysfunction and its severity grading(P<0.05). Conclusions In elderly patients, SS is independently associated with LV diastolic dysfunction. Echocardiographic detection of SS serves as a specific imaging clue for underlying LV diastolic impairment, and routine quantitative assessment of LV diastolic function is warranted in these patients.

Key words: sigmoid septum, left ventricular diastolic function, aged

中图分类号:

R541.4

王雅清, 柏颖, 杨笑熳, 孙敏, 王屹, 李静. 老年患者S型室间隔与左心室舒张功能的相关性研究[J]. 实用老年医学, 2026, 40(10): 1028-1033.

WANG Yaqing, BAI Ying, YANG Xiaoman, SUN Min, WANG Yi, LI Jing. Association between sigmoid septum and left ventricular diastolic function in elderly patients[J]. Practical Geriatrics, 2026, 40(10): 1028-1033.

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