影像组学在胰腺纤维化精准诊断与个性化干预中的研究进展

doi:10.3969/j.issn.1003-9198.2026.07.003

摘要/Abstract

摘要： 胰腺纤维化是慢性胰腺炎(chronic pancreatitis, CP)和胰腺癌的标志性病理特征,严重影响着老年人群的健康,并带来沉重的医疗负担。影像学检查是无创评估胰腺纤维化的重要手段,但传统影像模式在精确诊断纤维化程度及全面评估患者病情方面仍存在局限。近年来,影像组学的发展为实现胰腺纤维化的精准诊断和个体化干预提供了新的技术路径。本文对影像组学在胰腺纤维化疾病诊疗中的应用和进展进行了综述,重点探讨其在提升CP诊断效能、优化胰腺导管腺癌患者预后预测及个体化治疗决策中的作用,揭示了影像组学在改善老年人群胰腺健康方面的潜在价值。

关键词: 影像组学, 胰腺纤维化, 慢性胰腺炎, 胰腺癌, 胰腺导管腺癌

Abstract: Pancreatic fibrosis is a hallmark pathological feature of chronic pancreatitis (CP) and pancreatic cancer, severely affecting the health of the elderly population and imposing a heavy medical burden. While imaging examination serves as an important noninvasive approach for evaluating pancreatic fibrosis, conventional imaging modalities remain limited in accurately diagnosing fibrosis severity and comprehensively assessing disease status. In recent years, the advancement of radiomics has emerged as a novel technical avenue to facilitate precision diagnosis and personalized intervention for pancreatic fibrosis. This review systematically summarizes radiomics research in the context of pancreatic fibrosis diagnosis and management, with particular emphasis on its role in enhancing diagnostic performance for CP, optimizing prognostic prediction for patients with pancreatic ductal adenocarcinoma, and informing individualized therapeutic decision-making, thereby elucidating the potential value of radiomics in improving pancreatic health among the elderly population.

Key words: radiomics, pancreatic fibrosis, chronic pancreatitis, pancreatic cancer, pancreatic ductal adenocarcinoma

中图分类号:

R 587

梁钧程, 雷佳炜, 王佳贺. 影像组学在胰腺纤维化精准诊断与个性化干预中的研究进展[J]. 实用老年医学, 2026, 40(7): 658-661.

LIANG Juncheng, LEI Jiawei, WANG Jiahe. Research advances in radiomics for precision diagnosis and personalized intervention of pancreatic fibrosis[J]. Practical Geriatrics, 2026, 40(7): 658-661.

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