血清β2微球蛋白在心脑血管疾病中的研究进展

doi:10.3969/j.issn.1003-9198.2021.08.024

摘要/Abstract

中图分类号:

R 543

袁凯晴, 姜晓艳. 血清β2微球蛋白在心脑血管疾病中的研究进展[J]. 实用老年医学, 2021, 35(8): 879-882.

[1] GARIMELLA P S,LEE A K,AMBROSIUS W T,et al. Markers of kidney tubule function and risk of cardiovascular disease events and mortality in the SPRINT trial [J]. Eur Heart J,2019,40(42):3486-3493.
[2] WANG W,YUAN R,KORANTZOPOULOS P,et al. Cystatin C and risk of atrial fibrillation in elderly hypertensive patients without chronic kidney disease [J]. Int J Cardiol Heart Vasc,2016,212:262-264.
[3] ABID L,CHARFEDDINE S,KAMMOUN S,et al. Cystatin C: A prognostic marker after myocardial infarction in patients without chronic kidney disease [J]. J Saudi Heart Assoc,2016,28(3):144-151.
[4] KOH E S,LEE K,KIM S H,et al. Serum β2-Microglobulin predicts mortality in peritoneal dialysis patients: a prospective cohort study [J]. Am J Nephrol,2015,42(2):91-98.
[5] SELVIN E,JURASCHEK S P,ECKFELDT J,et al. Within-person variability in kidney measures [J]. Am J Kidney Dis,2013,61(5):716-722.
[6] SMITH L K,HE Y,PARK J S,et al. β2-microglobulin is a systemic pro-aging factor that impairs cognitive function and neurogenesis [J]. Nat Med,2015,21(8):932-937.
[7] KIM M K,YUN K J,CHUN H J,et al. Clinical utility of serum beta-2-microglobulin as a predictor of diabetic complications in patients with type 2 diabetes without renal impairment [J]. Diabetes Metab,2014,40(6):459-465.
[8] HILT Z T,PARISER D N,TURE S K,et al. Platelet-derived beta2M regulates monocyte inflammatory responses [J]. JCI Insight,2019,4(5):e122943.
[9] MATSUSHITA K,SANG Y,BALLEW S H,et al. Cardiac and kidney markers for cardiovascular prediction in individuals with chronic kidney disease [J]. Arterioscler Thromb Vasc Biol,2014,34(8):1770-1777.
[10] MATSUSHITA K,SANG Y,BALLEW S H,et al. Cardiac and kidney markers for cardiovascular prediction in individuals with chronic kidney disease: the atherosclerosis risk in communities study [J]. Arterioscler Thromb Vasc Biol,2014,34(8):1770-1777.
[11] MOCKEL M,MULLER R,SEARLE J,et al. Usefulness of Beta2-microglobulin as a predictor of all-cause and nonculprit lesion-related cardiovascular events in acute coronary syndromes (from the PROSPECT Study) [J]. Am J Cardiol,2015,116(7):1034-1040.
[12] ZHANG C,LI F,LONG T,et al. Beta 2-Microglobulin and the severity of coronary stenosis in patients with acute coronary syndrome [J]. Heart Lung Circ,2019,28(4):575-582.
[13] GROH L,KEATING S T,JOOSTEN L A B,et al. Monocyte and macrophage immunometabolism in atherosclerosis [J]. Semin Immunopathol,2018,40(2):203-214.
[14] LIBBY P,PASTERKAMP G,CREA F,et al. Reassessing the mechanisms of acute coronary syndromes [J]. Circ Res,2019,124(1):150-160.
[15] CREA F,LIBBY P. Acute coronary syndromes: the way forward from mechanisms to precision treatment [J]. Circulation,2017,136(12):1155-1166.
[16] MORRELL C N,AGGREY A A,CHAPMAN L M,et al. Emerging roles for platelets as immune and inflammatory cells [J]. Blood,2014,123(18):2759-2767.
[17] SHAO L,ZHANG Y,PAN X,et al. Knockout of beta-2 microglobulin enhances cardiac repair by modulating exosome imprinting and inhibiting stem cell-induced immune rejection [J]. Cell Mol Life Sci, 2020,77(5):937-952.
[18] FOSTER M C,CORESH J,HSU C Y,et al. Serum β-trace protein and β2-microglobulin as predictors of ESRD, Mortality, and cardiovascular disease in adults with CKD in the Chronic Renal Insufficiency Cohort (CRIC) Study [J]. Am J Kidney Dis,2016,68(1):68-76.
[19] YıLMAZ A,YıLMAZ B,KüçüKSEYMEN S. β-2 microglobulin level is negatively associated with global left ventricular longitudinal peak systolic strain and left atrial volume index in patients with chronic kidney disease not on dialysis [J]. Anatol J Cardiol,2016,16(11):844-849.
[20] VIANELLO A. beta2-microglobulin and TIMP1 are linked together in cardiorenal remodeling and failure [J]. Cardiorenal Med,2015,5(1):1-11.
[21] ZHOU X J,ZHANG X,ZHANG J,et al. Diagnostic value of growth differentiation factor-15 and β2-microglobulin in children with congenital heart disease combined with chronic heart failure and its relationship with cardiac function [J]. Eur Rev Med Pharmacol Sci,2020,24(15):8096-8103.
[22] WOJCIECHOWSKA C,WODNIECKI J,WOJNICZ R,et al. Neopterin and Beta-2 microglobulin relations to immunity and inflammatory status in nonischemic dilated cardiomyopathy patients [J]. Mediators Inflamm,2014,2014:585067.
[23] 陈月梅,蒋洪敏,张婷婷,等. 急性脑梗死患者血清同型半胱氨酸和β-2微球蛋白检测的临床意义 [J]. 国际检验医学杂志,2012,33(12):1489-1490.
[24] 刘洋,代瑞宁,史秀丽,等. 急性脑梗死患者血清胱抑素C和β2-微球蛋白水平的临床观察 [J]. 中国动脉硬化杂志,2016,24(4):405-408.
[25] SAEED F,ADIL M M,PIRACHA B H,et al. Acute renal failure worsens in-hospital outcomes in patients with intracerebral hemorrhage [J]. J Stroke Cerebrovasc Dis,2015,24(4):789-794.
[26] WANG R,HU H,HU S,et al. beta2-microglobulin is an independent indicator of acute kidney injury and outcomes in patients with intracerebral hemorrhage [J]. Medicine (Baltimore),2020,99(8):e19212.
[27] YANG R,FU S,ZHAO L,et al. Quantitation of circulating GDF-11 and β2-MG in aged patients with age-related impairment in cognitive function [J]. Clin Sci,2017,131(15):1895-1904.
[28] LEE H,BROTT B K,KIRKBY L A,et al. Synapse elimination and learning rules co-regulated by MHC class I H2-Db [J]. Nature,2014,509(7499):195-200.
[29] HOSSEINI L,FAROKHI-SISAKHT F,BADALZADEH R,et al. Nicotinamide mononucleotide and melatonin alleviate aging-induced cognitive impairment via modulation of mitochondrial function and apoptosis in the prefrontal cortex and hippocampus [J]. Neuron,2019,423:29-37.
[30] BUDNI J,BELLETTINI-SANTOS T,MINA F,et al. The involvement of BDNF, NGF and GDNF in aging and Alzheimer’s disease [J]. Aging Dis,2015,6(5):331-341.
[31] ZHONG Q,ZOU Y,LIU H,et al. Toll-like receptor 4 deficiency ameliorates β2-microglobulin induced age-related cognition decline due to neuroinflammation in mice [J]. Mol Brain,2020,13(1):20.
[32] SONG P,RUDAN D,ZHU Y,et al. Global, regional, and national prevalence and risk factors for peripheral artery disease in 2015: an updated systematic review and analysis [J]. Lancet Glob Health,2019,7(8):e1020-e1030.
[33] WILSON A M,KIMURA E,HARADA R K,et al. Beta2-microglobulin as a biomarker in peripheral arterial disease: proteomic profiling and clinical studies [J]. Circulation,2007,116(12):1396-1403.
[34] CHEUNG C L,LAM K S,CHEUNG B M. Serum β-2 microglobulin predicts mortality in people with diabetes [J]. Eur J Endocrinol,2013,169(1):1-7.

血清β2微球蛋白在心脑血管疾病中的研究进展

PDF (PC)

可视化

摘要/Abstract

引用本文

使用本文

参考文献

相关文章 15

Metrics

推荐阅读 10

[1]	陈映泉, 钟勇. 心血管老化的机制、标志物和治疗[J]. 实用老年医学, 2024, 38(3): 299-303.
[2]	范婷泳, 袁丽, 杨小玲, 陈茜. Caprini量表评估老年糖尿病病人静脉血栓栓塞症的效果[J]. 实用老年医学, 2023, 37(12): 1233-1237.
[3]	张授尧, 张星贺, 夏世金. 血管衰老与老年血管疾病[J]. 实用老年医学, 2023, 37(10): 973-977.
[4]	白晓瑜, 张君, 赵鹏, 魏梅, 邱亚辉, 冯雪娟. 5次坐立试验与老年PCI病人心功能及生活质量的相关性研究[J]. 实用老年医学, 2023, 37(8): 777-780.
[5]	高伟飞, 李鹏, 乔镇, 马利娜. Padua评分对老年住院病人发生静脉血栓栓塞症的预测价值[J]. 实用老年医学, 2023, 37(8): 803-805.
[6]	王朝阳, 赵丽娜, 梁浩, 陈淑霞, 谷剑. 纤维蛋白原与白蛋白比值对老年疑似冠心病病人冠脉病变程度的预测价值[J]. 实用老年医学, 2023, 37(8): 806-810.
[7]	杨少琦, 杨洋, 邓丽娜, 翟志欣. 系统免疫炎症指数对老年射血分数减低型心力衰竭病人下肢深静脉血栓形成的预测价值[J]. 实用老年医学, 2023, 37(7): 695-699.
[8]	陈顺中. 慢性脑供血不足的中医治疗研究进展[J]. 实用老年医学, 2023, 37(2): 124-127.
[9]	崔娟, 郑俊晨. 外周血尿路上皮癌抗原1、脂蛋白(a)在老年急性心肌梗死病人中的诊断价值[J]. 实用老年医学, 2021, 35(12): 1273-1276.
[10]	周艳, 翁艳敏. 1例老年主动脉穿透性溃疡合并颈动脉夹层并发急性脑动脉栓塞的护理[J]. 实用老年医学, 2021, 35(11): 1209-1211.
[11]	张玥, 谭晓. 冠状动脉慢血流现象临床相关危险因素分析[J]. 实用老年医学, 2021, 35(10): 1019-1022.
[12]	郭万申, 樊双义. 老年心脑血管疾病病人颈动脉斑块与体质量指数、生长激素之间的关系[J]. 实用老年医学, 2021, 35(9): 935-938.
[13]	王铭, 孙瑞红. 巨噬细胞极化在动脉粥样硬化进程中的研究进展[J]. 实用老年医学, 2021, 35(9): 975-977.
[14]	王凯, 范小璇, 王欢, 杨永锋, 马思田, 赵晓平. 血管老化发生机制及相关靶点的研究进展[J]. 实用老年医学, 2021, 35(7): 750-753.
[15]	殷亚昕, 刘润梅, 翟红霞, 李良, 张津津, 陈海威, 王磊, 李娜, 夏云峰. 辛伐他汀对动脉粥样硬化大鼠高迁移率族蛋白1表达的影响[J]. 实用老年医学, 2010, 24(2): 128-131.