老年女性骨质疏松性骨折病人再次骨折的危险因素分析

doi:10.3969/j.issn.1003-9198.2021.07.017

摘要/Abstract

摘要： 目的探讨老年女性骨质疏松性骨折病人再次骨折的危险因素。方法回顾性分析2018年9月至2020年1月我院收治的老年女性骨质疏松性骨折病人85例,根据是否为再次骨折分为再次骨折组(45例)和新发骨折组(40 例)。对2组病人的基本资料和临床资料进行比较,采用多因素Logistic回归分析老年女性骨质疏松性骨折病人再次骨折的风险因素。结果 2组年龄、BMI、骨密度(BMD)、平卧至站位转换时间及血清总碱性磷酸酶(TALP)水平差异有统计学意义(P＜0.05)。多因素Logistic回归分析显示,年龄≥75岁(OR=1.612,95%CI: 1.129~8.994)、BMI≤21.00 (OR= 1.725,95%CI: 1.160~5.338)、BMD的T值＜-3.50 (OR=2.125,95%CI: 1.815~4.888)、平卧至站位转换时间≥20 s(OR=1.688,95%CI: 1.009~3.228)及TALP≥110.00 μg/L(OR=1.123,95%CI: 1.015~2.177) 是老年女性骨质疏松性骨折病人再次骨折的危险因素。结论年龄大、BMI和BMD较低、平卧至站位转换时间较长及TALP水平升高均是老年女性骨质疏松性骨折病人再次骨折的独立危险因素。

关键词: 老年女性, 骨质疏松, 再次骨折, 危险因素

Abstract: Objective To investigate the risk factors for re-fracture after osteoporotic fracture in the elderly women. Methods A retrospective analysis of 85 elderly women with osteoporotic fractures admitted to our hospital from September 2018 to January 2020 were divided into re-fracture group(n=45) and new fracture group (n=40). The basic data and clinical data of the two groups were compared, and the risk factors of re-fracture after osteoporotic fracture were analyzed by multivariate Logistic regression analysis. Results There were significant difference in the age, body mass index (BMI), bone mineral density(BMD), transition time from supine to standing position and total alkaline phosphatase(TALP) between the two groups (P<0.05). Multivariate Logistic regression analysis showed that the risk factors for re-fracture after osteoporotic fracture in the elderly women were age ≥75 years (OR=1.612, 95%CI: 1.129-8.994), BMI ≤21.00 (OR=1.725, 95%CI: 1.160-5.338), T value of BMD＜-3.50 (OR=2.125, 95%CI: 1.815-4.888), the transition time from supine to standing position≥20 s (OR=1.688, 95%CI: 1.009-3.228) and TALP≥110.00 μg/L (OR=1.123, 95%CI: 1.015-2.177). Conclusions Older, less BMI and BMD, longer transition time from supine to standing position, and increased TALP level are the independent risk factors of re-fractures after osteoporotic fractures in the elderly women.

Key words: elderly women, osteoporosis, re-fracture, risk factor

中图分类号:

R 683

纪虹, 张玉勤, 张春琰, 杨志梅, 李颖. 老年女性骨质疏松性骨折病人再次骨折的危险因素分析[J]. 实用老年医学, 2021, 35(7): 731-733.

JI Hong, ZHANG Yu-qin, ZHANG Chun-yan, YANG Zhi-mei, LI Ying. Analysis of risk factors for re-fracture after osteoporotic fracture in elderly women[J]. Practical Geriatrics, 2021, 35(7): 731-733.

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