老年心房颤动患者跌倒发生率及影响因素的meta分析

doi:10.3969/j.issn.1003-9198.2026.08.007

Abstract

Abstract: Objective To systematically evaluate the incidence and expplore the influencing factors of falls in elderly patients with atrial fibrillation (AF), providing evidence-based guidance for fall prevention. Methods Literature on the incidence and/or influencing factors of falls in elderly AF patients was systematically searched in Chinese and English databases (CNKI, Wanfang, VIP, Sinomed, PubMed, Web of Science, Cochrane Library, CINAHL). The search period spanned from database inception to January 2025. Two researchers independently screened and extracted data. Meta-analysis was performed using Stata 16.0. Results Nine studies involving 228 821 elderly AF patients were included. Meta-analysis revealed a pooled fall incidence of 19%(95%CI: 15%-23%)in the elderly AF patients. Subgroup analysis showed higher fall incidence in cross-sectional studies (51%) compared to cohort studies (10%), in studies with follow-up durations ≥3 years (22%) versus <3 years (6%). For influencing factors, meta-analysis identified amiodarone use as an independent risk factor for falls(OR =2.84, 95%CI: 1.42-5.65, P<0.01). Benzodiazepines, cardiovascular diseases, musculoskeletal diseases, and advanced age also showed trends toward increased fall risk, though these associations were not statistically significant (P>0.05). Conclusions Elderly AF patients exhibit a high incidence of falls, with amiodarone identified as an independent risk factor. Medication review and comprehensive comorbidity management should be integrated into fall prevention strategies in AF management.

Key words: atrial fibrillation, falls, aged, incidence, risk factors, meta-analysis

CLC Number:

R 541.75

WANG Xuefei, KANG Shengqin, WANG Wei, WANG Jie, CAI Cuichun. Meta-analysis of incidence and influencing factors of falls in elderly patients with atrial fibrillation[J]. Practical Geriatrics, 2026, 40(8): 787-792.

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Meta-analysis of incidence and influencing factors of falls in elderly patients with atrial fibrillation

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