Practical Geriatrics ›› 2026, Vol. 40 ›› Issue (8): 811-815.doi: 10.3969/j.issn.1003-9198.2026.08.011

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Predictive value of residual cholesterol inflammation index for the prognosis in elderly patients with unstable angina pectoris

LI Yangbo, ZHAO Zhengkun   

  1. Department of Cardiovascular Medicine, Xianyang Hospital of Yan’an University, Xianyang 712000, China (LI Yangbo); Department of Cardiovascular Medicine, Xi’an First Hospital, Xi’an 712000, China (ZHAO Zhengkun)
  • Received:2026-02-14 Online:2026-08-20 Published:2026-08-24
  • Contact: ZHAO Zhengkun,Email: zzk215830@163.com

Abstract: Objective To explore the predictive value of the residual cholesterol inflammatory index (RCII) for the prognosis in the elderly patients with unstable angina pectoris (UAP). Methods A total of 102 elderly UAP patients admitted to Xianyang Hospital of Yan’an University from January 2024 to December 2024 were selected. Baseline data of all patients were collected, and the value of RCII was calculated. All patients received standardized treatment and completed a 1-year follow-up, with the occurrence of major adverse cardiovascular events (MACE) as the endpoint. Based on follow-up results, the patients were divided into a good prognosis group (n=66) and an poor prognosis group (n=36). Multivariate logistic regression analysis was used to identify factors influencing the prognosis in the elderly UAP patients, and the receiver operating characteristic (ROC) curve was employed to evaluate the predictive value of RCII for prognosis. Results Among the 102 elderly UAP patients, 36 cases (35.29%) experienced MACE. The age, global registry of acute coronary events (GRACE) score, proportion of prior percutanous coronary intervention (PCI) history, levels of residual cholesterol(RC), high-sensitivity C-reactive protein (hs-CRP), and RCII were significantly higher in the poor prognosis group than those in the good prognosis group (P<0.05). Multivariate logistic regression analysis revealed that RC (OR=2.006, 95%CI: 1.143-3.520), hs-CRP (OR=2.040, 95%CI: 1.240-3.356), GRACE score (OR=2.356, 95%CI: 1.372-4.047), and RCII (OR=2.798, 95%CI: 1.738-4.505) were independent risk factors for the prognosis of elderly UAP patients. ROC curve analysis demonstrated that the AUC values of RC, hs-CRP, and RCII for predicting prognosis in elderly patients with UAP were 0.792,0.804, and 0.917, respectively. Conclusions RCII is an effective novel composite indicator for predicting the prognosis of elderly UAP patients, with superior predictive performance compared to single RC or inflammatory markers, and has potential to guide clinical risk stratification and early intervention.

Key words: unstable angina pectoris, aged, residual cholesterol inflammation index, prognosis, predictive value

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