[1] HÖHN A,WEBER D,JUNG T,et al. Happily (n)ever after: aging in the context of oxidative stress, proteostasis loss and cellular senescence[J]. Redox Biol,2017, 11: 482-501. [2] CSEKES E, RAČKOVÁ L. Skin aging, cellular senescence and natural polyphenols[J]. Int J Mol Sci,2021, 22(23):12641. [3] ECKHART L, ZEEUWEN P L. The skin barrier: epidermis vs environment[J]. Exp Dermatol, 2018, 27(8):805-806. [4] GRUBER F, KREMSLEHNER C, ECKHART L, et al. Cell aging and cellular senescence in skin aging -recent advances in fibroblast and keratinocyte biology[J]. Exp Gerontol,2020, 130:110780. [5] 王侠生,徐金华,张学军,等.现代皮肤病学[M]. 上海:上海大学出版社,2020:48. [6] 刘悠云,仲辉.皮肤时序性衰老与光老化[J]. 中国化妆品,2022, 12 (1):82-85. [7] RUSSELL-GOLDMAN E, MURPHY G F. The pathobiology of skin aging: new insights into an old dilemma[J]. Am J Pathol,2020, 190(7):1356-1369. [8] TODOROVA K,MANDINOVA A. Novel approaches for managing aged skin and nonmelanoma skin cancer [J]. Adv Drug Deliv Rev,2020,153(12):18-27. [9] 朱姗,赵志月,王子静,等.皮肤老化分子机制及中药防治皮肤老化研究进展[J]. 天津中医药大学学报,2021,40(4):431-439. [10] BOISMAL F, SERROR K, DOBOS G, et al. Skin aging: pathophysiology and innovative therapies [J]. Med Sci:Paris,2020, 36(12):1163-1172. [11] VICTORELLI S, LAGNADO A, HALIM J,et al. Senescent human melanocytes drive skin ageing via paracrine telomere dysfunction[J]. EMBO J, 2019, 38(23):e101982. [12] FITSIOU E, PULIDO T, CAMPISI J, et al. Cellular senescence and the senescence-associated secretory phenotype as drivers of skin photoaging[J]. J Invest Dermatol, 2021,141(4S):1119-1126. [13] Franco A C, Aveleira C, Cavadas C. Skin senescence: mechanisms and impact on whole-body aging[J]. Trends Mol Med, 2022,28(2):97-109. [14] BAUMANN L. How to use oral and topical cosmeceuticals to prevent and treat skin aging[J]. Facial Plast Surg Clin North Am, 2018, 26(4): 407-413. [15] STRATIGI K, CHATZIDOUKAKI O, GARINIS G A. DNA damage-induced inflammation and nuclear architecture[J]. Mech Ageing Dev,2017,165(Pt A):17-26. [16] LI T, CHEN Z J. The cGAS-cGAMP-STING pathway connects DNA damage to inflammation, senescence, and cancer[J]. J Exp Med, 2018,215(5):1287-1299. [17] MCCABE M C, HILL R C, CALDERONE K, et al. Alterations in extracellular matrix composition during aging and photoaging of the skin[J]. Matrix Biol Plus,2020,8: 100041. [18] WEIHERMANN A C, DE CARVALHO C M, SCHUCK D C, et al. Modulation of photoaging-induced cutaneous elastin: evaluation of gene and protein expression of markers related to elastogenesis under different photoexposure conditions[J]. Derm Ther:Heidelb, 2021,11(6):2043-2056. [19] BLOKLAND K E C, POUWELS S D, SCHULIGA M, et al. Regulation of cellular senescence by extracellular matrix during chronic fibrotic diseases[J]. Clin Sci:Lond, 2020, 134(20):2681-2706. [20] OBRADOR E, LIU-SMITH F, DELLINGER R W, et al. Oxidative stress and antioxidants in the pathophysiology of malignant melanoma[J]. Biol Chem, 2019, 400(5):589-612. [21] MAZAT J P, DEVIN A, RANSAC S. Modelling mitochondrial ROS production by the respiratory chain[J]. Cell Mol Life Sci, 2020, 77(3):455-465. [22] RINNERTHALER M, BISCHOF J, STREUBEL M K, et al. Oxidative stress in aging human skin[J]. Biomolecules, 2015, 5(2):545-589. [23] FORRESTER S J, KIKUCHI D S, HERNANDES M S, et al. Reactive oxygen species in metabolic and inflammatory signaling[J]. Circ Res, 2018, 122(6):877-902. [24] VERMEIJ W P, ALIA A, BACKENDORF C. ROS quenching potential of the epidermal cornified cell envelope[J]. J Investig Dermatol, 2011, 131(7): 1435-1441. [25] LIU T, SUN L, ZHANG Y, et al. Imbalanced GSH/ROS and sequential cell death[J]. J Biochem Mol Toxicol, 2022, 36(1):e22942. [26] QUAN Y, XIN Y, TIAN G, et al. Mitochondrial ROS-modulated mtDNA: a potential target for cardiac aging[J]. Oxid Med Cell Longev, 2020:9423593. [27] KAMMEYER A, LUITEN R M. Oxidation events and skin aging[J]. Ageing Res Rev, 2015, 21:16-29. [28] TUDEK B, ZDZ.ALIK-BIELECKA D, TUDEK A, et al. Lipid peroxidation in face of DNA damage, DNA repair and other cellular processes[J]. Free Radic Biol Med, 2017, 107:77-89. [29] LENNICKE C, COCHEMÉ H M. Redox metabolism: ROS as specific molecular regulators of cell signaling and function[J]. Mol Cell, 2021, 81(18):3691-3707. [30] BIRCH-MACHIN M A, BOWMAN A. Oxidative stress and ageing[J]. Br J Dermatol, 2016, 175(Suppl 2):26-29. [31] PETRUK G, DEL GIUDICE R, RIGANO M M, et al. Antioxidants from plants protect against skin photoaging[J]. Oxid Med Cell Longev, 2018:1454936. [32] CHEN T, HOU H, FAN Y, et al. Protective effect of gelatin peptides from pacific cod skin against photoaging by inhibiting the expression of MMPs via MAPK signaling pathway[J]. J Photochem Photobiol B, 2016, 165:34-41. [33] WANG Y, WANG L, WEN X, et al. NF-κB signaling in skin aging[J]. Mech Ageing Dev, 2019, 184:111160. [34] KAMMEYER A, LUITEN R M. Oxidation events and skin aging[J]. Ageing Res Rev, 2015, 21:16-29. [35] LEE S, SCHMITT C A. The dynamic nature of senescence in cancer[J]. Nat Cell Biol, 2019, 21(1):94-101. [36] CUOLLO L, ANTONANGELI F, SANTONI A, et al. The senescence-associated secretory phenotype (SASP) in the challenging future of cancer therapy and age-related diseases[J]. Biology:Basel, 2020, 9(12):485. [37] CALCINOTTO A, KOHLI J, ZAGATO E, et al. Cellular senescence: aging, cancer, and injury[J]. Physiol Rev, 2019, 99(2):1047-1078. [38] TANG R, LI Q, WANG D, et al. Modernization of traditional medicine the protective effect of dendrobium officinale polysaccharides on photoaging fibroblasts by scavenging reactive oxygen species and promoting the expression of TGF-β1[J]. Traditional Med Res, 2018, 3:131-139. [39] MCHUGH D, GIL J. Senescence and aging: causes, consequences, and therapeutic avenues[J]. J Cell Biol, 2018, 27(1):65-77. [40] PILKINGTON S M, BULFONE-PAUS S, GRIFFITHS C E M, et al. Inflammaging and the skin[J]. J Invest Dermatol, 2021, 141(4S):1087-1095. [41] MCCART E A, THANGAPAZHAM R L, LOMBARDINI E D, et al. Accelerated senescence in skin in a murine model of radiation-induced multi-organ injury[J]. J Radiat Res, 2017, 58(5): 636-646. [42] LEE Y I, CHOI S, ROH W S, et al. Cellular senescence and inflammaging in the skin microenvironment[J]. Int J Mol Sci, 2021, 22(8):3849. [43] WLASCHEK M, MAITY P, MAKRANTONAKI E, et al. Connective tissue and fibroblast senescence in skin aging[J]. J Investig Dermatol, 2021, 141(4S): 985-992. [44] MEYER P, MAITY P, BURKOVSKI A, et al. A model of the onset of the senescence associated secretory phenotype after DNA damage induced senescence[J]. PLoS Comput Biol, 2017, 13(12):e1005741. [45] FITSIOU E, PULIDO T, CAMPISI J, et al. Cellular senescence and the senescence-associated secretory phenotype as drivers of skin photoaging[J]. J Investig Dermatol, 2020, 141(4S): 1119-1126. [46] VICTORELLI S, LAGNADO A, HALIM J, et al. Senescent human melanocytes drive skin ageing via paracrine telomere dysfunction[J]. EMBO J, 2019, 38(23): e101982. [47] CHEN T, HOU H, FAN Y, et al. Protective effect of gelatin peptides from pacific cod skin against photoaging by inhibiting the expression of MMPs via MAPK signaling pathway[J]. J Photochem Photobiol B Biol, 2016, 165:34-41. [48] GU Y, HAN J, JIANG C, et al. Biomarkers, oxidative stress and autophagy in skin aging[J]. Ageing Res Rev, 2020, 59:101036. [49] KANTA J. Collagen matrix as a tool in studying fibroblastic cell behavior[J]. Cell Adh Migr, 2015, 9(4):308-316. [50] MENG X M, NIKOLIC-PATERSON D J, LAN H Y. TGF-β: the master regulator of fibrosis[J]. Nat Rev Nephrol, 2016, 12(6):325-338. |