Abstract: Objective To explore the influencing factors of illness perception in the elderly patients with Parkinson's disease (PD) after deep brain stimulation surgery (DBS). Methods A cross-sectional study was conducted in 80 patients with PD aged >65 years old from January 2020 to January 2021. The illness perception,physician trust and personality characteristics of the patients were measured by Illness Perception Questionnaire Revised Edition (IPQ-R), the Wake Forest Physician Trust Scale (WFPTS) and Eysenck Personality Questionaire (EPQ), respectively. The illness perception score among the patients with different educational background,disease course and gender was compared, and the correlation of the patients' illness perception with physician trust and personality characteristics was analyzed. Results There were no significant difference in overall illness perception scores among the patients with different educational background,disease course and gender. The individual control of males was significantly lower than that of females (t=-2.03, P=0.045). Pearson correlation analysis showed a significant negative correlation between perceive disease outcome, treatment control, disease cycle, emotional statement score and physician trust, respectively (r =-0.23, -0.22, -0.24, -0.34, all P<0.05). The total score of personality evaluation,internal and external orientation,emotionality, self-concealment scores were positively correlated with the score of illness perceived consequences dimension (r=0.25, 0.27, 0.25, 0.24, all P<0.05); The total score of personality evaluation,internal and external orientation,psychoticism and self-concealed were negatively correlated with the score of individual control dimension of illness perception (r=-0.24, -0.26, -0.24, -0.25, all P<0.05). Conclusions Education background and course of the disease have no significant influence on patients' illness perception,and the individual control ability of patients with different genders is different. Physician trust and their personalities significantly influence the illness perception of the elderly patients with PD after DBS.

Key words: deep brain stimulation, program control, Parkinson's disease, illness perception, influencing factors