Practical Geriatrics ›› 2022, Vol. 36 ›› Issue (12): 1247-1250.doi: 10.3969/j.issn.1003-9198.2022.12.015

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Analysis of clinical characteristics and related risk factors of heart failure with preserved ejection fraction in elderly patients with hypertension

ZHANG Ming-rui, CUI Wen-xia, GAO Lei, LI Man, HU yun   

  1. Department of Geriatrics, Nanjing Drum Tower Hospital Clinical College of Nanjing Medical University, Nanjing 210008, China
  • Received:2022-02-18 Online:2022-12-20 Published:2022-11-30

Abstract: Objective To investigate the clinical characteristics and related risk factors of heart failure with preserved ejection fraction (HFpEF) in the elderly patients with hypertension. Methods A total of 569 elderly patients with hypertension were enrolled in this study. According to whether presenting with HFpEF, the patients were divided into HFpEF group and control group. The clinical characteristics of the two groups were analyzed. Multiple Logistic regression was used to analyze the risk factors of HFpEF in the elderly patients with hypertension. Results The age, proportion of female, overweight, type 2 diabetes mellitus, serum levels of B type natriuretic peptide, urea nitrogen and creatinine in HFpEF group were significantly higher than those in control group (P< 0.05). The diastolic ventricular septal thickness, diastolic left ventricular diameter, diastolic left ventricular posterior wall thickness, left atrial diameter and left ventricular mass index in HFpEF group were significantly higher than those in control group (P < 0.01). Logistic regression analysis showed that the related risk factors of HFpEF in the elderly hypertensive patients included female, overweight, type 2 diabetes mellitus and left ventricular mass index. Conclusions The incidence of HFpEF might be influenced by gender, overweight, type 2 diabetes mellitus and left ventricular mass index in the elderly hypertensive patients.

Key words: hypertension, heart failure with preserved ejection fraction, clinical characteristics

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