Abstract: Objective To study the risk factors of persistent atrial fibrillation (AF) in the patients with heart failure with reduced ejection fraction (HFrEF ). Methods Totally 78 patients with HFrEF admitted in Gaochun People's Hospital from January to December 2017 were collected. According to the type of AF,the patients were divided into paroxysmal AF group (n=16)and persistent AF group (n=62). The risk factors for persistent AF were analyzed by multivariate Logistic regression analysis and receiver operator characteristic(ROC)curve analysis respectively. Results The levels of left atrial diameter (LAD), uric acid and the prevalence of type 2 diabetes were higher, and the level of body mass index, the prevalence of valvular heart disease were lower in persistent AF group than those in paroxysmal AF group(P＜0. 05). Multivariate Logistic regression analysis showed that LAD was the independent risk factor for patients with persistent AF(OR=1. 256,95%CI:1. 071-1. 473). ROC curve revealed that optimal cut-off point of LAD was 49. 5 mm, and area under ROC curve was 0. 871 with sensitivity and specificity of 51. 6% and 41. 5%. Conclusions LAD is an independent risk factor for persistent AF in the patients with HFrEF.
   

Key words: paroxysmal atrial fibrillation, persistent atrial fibrillation, risk factor, left atrial diameter