膳食炎症指数预测老年慢性阻塞性肺疾病患者并发肌少症风险的研究

doi:10.3969/j.issn.1003-9198.2026.01.011

摘要/Abstract

摘要： 目的探讨膳食炎症指数(dietary inflammatory index, DII)与老年COPD患者并发肌少症的相关性。方法入选2023年于铜陵市人民医院老年医学科就诊的老年COPD患者212例,采用半定量食物频率调查表(semi-quantitative food frequency questionnaire, SFFQ)评估患者的饮食模式,计算DII评分。随访观察12个月,检测患者骨骼肌质量、握力及6 m步行速度,分析DII评分与老年COPD患者并发肌少症风险的相关性。结果入选患者平均年龄为(75.18±5.91)岁,DII为0.98±2.22。随访12个月,肌少症的患病率为26.89%。与非肌少症患者相比,并发肌少症的患者基线年龄更高、BMI更低、营养不良比例更高,且DII评分值亦更高(P<0.05)。多因素logistic回归分析显示,在校正了混杂因素后,DII评分仍然是老年COPD患者并发肌少症的独立危险因素(校正HR=1.34, 95%CI:1.12~1.60, P=0.001)。结论高DII评分是老年COPD患者并发肌少症的独立危险因素,通过改善膳食结构降低DII评分可能是预防老年COPD患者罹患肌少症的潜在手段。

关键词: 慢性阻塞性肺疾病, 老年人, 膳食炎症指数, 肌少症

Abstract: Objective To explore the predictive effects of dietary inflammatory index (DII) on the onset of sarcopenia in the elderly patients with chronic obstructive pulmonary disease (COPD). Methods A total of 212 patients with COPD were enrolled from the Department of Geriatrics of Tongling People’s Hospital from January to December 2023. The dietary pattern and DII score were evaluated by semi-quantitative food frequency questionnaire (SFFQ). After a follow-up of 12 months, the muscle mass, grip strength, and gait speed were examined. The association of DII score with the onset of sarcopenia was further investigated. Results The average age of the enrolled patients was 75.18±5.91 years. The DII score was 0.98±2.22. The incidence rate of sarcopenia was 26.89%. When compared to those without sarcopenia, patients with sarcopenia were older, and had lower levels of body mass index and higher proportion of malnutrition, as well as higher levels of DII score at baseline (P<0.05). Further multiple logistic regression analysis demonstrated that the association of high DII score with increased risk of sarcopenia remained significant even after adjustment for confounding factors (adjusted HR=1.34, 95%CI: 1.12-1.60, P=0.001). Conclusions High DII score is associated with increased risk of sarcopenia in elderly patients with COPD. Dietary interventions with low DII score may have beneficial effect on the prevention of sarcopenia in the elderly patients with COPD.

Key words: chronic obstructive pulmonary disease, aged, dietary inflammatory index, sarcopenia

中图分类号:

R 563
R 685

周敏, 周健坤. 膳食炎症指数预测老年慢性阻塞性肺疾病患者并发肌少症风险的研究[J]. 实用老年医学, 2026, 40(1): 53-56.

ZHOU Min, ZHOU Jiankun. Predictive effect of dietary inflammatory index on the onset of sarcopenia in elderly patients with chronic obstructive pulmonary disease[J]. Practical Geriatrics, 2026, 40(1): 53-56.

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