【Ａｂｓｔｒａｃｔ】 ＯｂｊｅｃｔｉｖｅTo research the safety and efficacy of high concentration potassium chloride infusion with micropump through central vein in aged patients with severe hypokalemia.ＭｅｔｈｏｄｓFortytwo elderly patients with severe hypokalemia were randomly divided into two groups: experimental group and control group.Patients in the experimental group were treated with micropump infusion of 6% KCl solution through central vein while the control group were treated with 03% KCl solution. Both groups were infused at the speed of 1-15 g/h KCl. Responses to the treatment in two groups were observed.ＲｅｓｕｌｔｓWhen the potassium concentration rose to 3.0 mmol/L, patients in experimental group spent 395±257 h, and 405±188 g KCl,and 115±25 ml liquid was infused, compared with 723±445 h, 836±378 g, 2054±1250 ml in control group. To relieve the pernicious arrhythmia caused by hypokalemia,the experiment group spent 122±035 h, compared with 255±086 h in the control group. All of the above figures had statistic difference between the two groups (P＜005). However, to raise the blood potassium to 45 mmol/L, the two groups patients had been infused with KCl 355±123 g and 416±15.5 g respectively, with no statistical difference (P＞005).ＣｏｎｃｌｕｓｉｏｎｓIn aged patients with severe hypokalemia, high concentration potassium chloride infusion with micropump through central vein was safe and effective.
