Table of Content

20 September 2026, Volume 40 Issue 9 Previous Issue   

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Application progress of virtual reality technology in palliative care for non-cancer patients JIA Yuchen, LIU Jiye 2026, 40 (9):  867-872.  doi: 10.3969/j.issn.1003-9198.2026.09.002 Abstract ( 13 )   PDF (1182KB) ( 23 )   Save Palliative care is a clinical treatment approach targeted at patients with severe illnesses and their families. Through early and precise assessment, it delivers effective management of pain and other symptoms, addresses physical, social, psychological and spiritual needs, and aims to alleviate and prevent suffering among patients and their relatives. With the accelerated aging of China’s population, the demand for palliative care has risen markedly. As an emerging digital non-pharmacological intervention, virtual reality (VR) technology distracts patients via virtual scenarios to relieve discomfort, and has been widely applied in rehabilitation management for various diseases. Relevant explorations integrating VR with palliative care have been carried out overseas, whereas clinical practices in this field remain immature domestically. This article systematically reviews the progress in the application of VR technology, both domestically and internationally, for four types of non-cancerous diseases—chronic obstructive pulmonary disease(COPD), cardiovascular disease, dementia, and end-stage renal disease—and provides an in-depth discussion of the current efficacy of these applications and the challenges that remain. Future research should focus on developing standardized diagnostic and treatment protocols, establishing multidisciplinary collaborative care mechanisms, and continuously optimizing and promoting the application of VR technology in palliative care for non-cancer patients. References | Related Articles | Metrics

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Progress in the application of human-computer interaction technology in palliative care for non-cancer patients SUN Yuxin, ZHANG Xiaolin 2026, 40 (9):  873-876.  doi: 10.3969/j.issn.1003-9198.2026.09.003 Abstract ( 15 )   PDF (1116KB) ( 20 )   Save Palliative care is an interdisciplinary field that integrates clinical medicine, psychology, nursing, and many other related disciplines. In recent years, it has garnered widespread attention in the medical field, with increased focus on non-cancer patients. As an important branch of computer science, the application and expansion of human-computer interaction technologies in the medical field can greatly facilitate home-based medical care delivery, significantly contributing to the development of palliative care. By summarizing the applications of various human-computer interaction technologies in the medical field of palliative care, this article provides an outlook on the future development direction of interactive technology, aiming to offer reference for relevant clinical practice. References | Related Articles | Metrics

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Advances in research on the application of telehealth in palliative care for non-cancer patients ZHANG Fei, WANG Zhong, WANG Jiahe 2026, 40 (9):  877-882.  doi: 10.3969/j.issn.1003-9198.2026.09.004 Abstract ( 10 )   PDF (1152KB) ( 23 )   Save Palliative care (PC) is a type of care that combines medical treatment with humanistic support. It aims to relieve pain and other distressing symptoms in patients with life-limiting illnesses and provide continuous support for patients and their families. With population aging and the increasing burden of non-cancer diseases such as chronic obstructive pulmonary disease, heart failure, and end-stage renal disease, the need for PC services among non-cancer patients is increasing. However, the shortage and uneven distribution of related medical resources have limited the development and application of PC for non-cancer patients. Telehealth uses information and communication technologies to provide remote care, monitoring, and follow-up. It offers a new way to extend PC services for non-cancer patients to homes and communities. Current studies show that telehealth has been widely used in symptom assessment and monitoring, remote consultation and follow-up, advance care planning, psychosocial support, and bereavement counseling. It may help reduce symptom burden, improve quality of life, support family caregivers, and improve the use of medical resources. However, its use in PC for non-cancer patients still faces several challenges, such as poor digital infrastructure, limited digital literacy among patients and families, limited applicability in complex clinical situations, and concerns about trust in technology. In the future, more policy support and high-quality research are needed. Future development of telehealth in PC for non-cancer patients should be adapted to China’s current PC system, traditional cultural context, and patient care characteristics, thereby promoting its standardized, continuous, and large-scale implementation. References | Related Articles | Metrics

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Research progress of machine learning in palliative care for non-cancer patients LI Minglin, LIANG Qingjing, ZENG Sanlong, LI Minfeng, LUO Jianwen 2026, 40 (9):  883-887.  doi: 10.3969/j.issn.1003-9198.2026.09.005 Abstract ( 11 )   PDF (1155KB) ( 22 )   Save Palliative care is an active practice of whole-person care, aimed at alleviating the physical and psychological suffering of patients, their families, and caregivers, thereby improving quality of life. Against the backdrop of an aging population, patients with non-cancer chronic diseases have become the primary recipients of palliative care services. These patients typically experience prolonged disease courses, significant fluctuations in condition, and difficulty in identifying the terminal phase. Traditional manual assessment models lead to delayed care interventions, suboptimal resource allocation, and insufficient precision in interventions. Machine learning has the potential to deeply mine multi-source medical data, thereby facilitating the intelligent transformation of palliative care. This review summarizes the current applications and existing challenges of machine learning in palliative care of non-cancer patients, aiming to provide a reference for clinical practice and research in this field. References | Related Articles | Metrics

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Research progress on the application of smart furniture technology in palliative care for non-cancer patients LIU Yuan, GUO Ying 2026, 40 (9):  888-892.  doi: 10.3969/j.issn.1003-9198.2026.09.006 Abstract ( 10 )   PDF (1173KB) ( 21 )   Save Palliative care is an approach that improves the quality of life of patients with life-threatening diseases and their families through early identification and active management of pain and other physical, psychological, social, and spiritual problems. The demand for home-based palliative care among non-cancer patients is increasingly prominent, yet traditional home care has limitations in continuous monitoring and abnormality detection capabilities. Smart furniture technology, by embedding sensing, risk warning, and automatic adjustment functions into everyday living objects, can provide support in symptom monitoring, postural support, fall prevention, pressure injury prevention, and caregiver burden reduction. This article systematically reviews the application progress of smart furniture technology in palliative care for non-cancer patients and discusses the existing problems, aiming to provide a reference for future research and clinical practice. References | Related Articles | Metrics

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Moderate-intensity aerobic exercise improves skeletal muscle function in aging mice by promoting collagen fiber proliferation WANG Xinxin, MAO Luxi, WANG Jingxin 2026, 40 (9):  893-899.  doi: 10.3969/j.issn.1003-9198.2026.09.007 Abstract ( 11 )   PDF (2160KB) ( 22 )   Save Objective To compare the effects of different intensities of aerobic exercise protocols on improving skeletal muscle function in aging mice. Methods Using a random number table, eighteen male C57BL/6 mice (12-15 months old) were randomly divided into three groups: the blank control group (control group), the moderate-intensity aerobic exercise group (moderate-intensity group) and the high-intensity aerobic exercise group (high-intensity group), with six mice in each group. The control group was cage-housed without exercise intervention. While mice in the moderate-intensity group and high-intensity group first received adaptive training according to the established exercise protocol, then completed 8 weeks of aerobic exercise training following different aerobic exercise protocols. After training, skeletal muscle motor function was evaluated via grip strength, exhaustive swimming, and gait analysis. Molecular changes in skeletal muscle fibers were assessed by HE staining, Polymerase Chain Reaction(PCR) and Western blot. Results The moderate-intensity group exhibited significantly increased grip strength in both forelimbs and hindlimbs, prolonged swimming endurance, increased walking and swing speeds, shortened swing duration and increased step width after intervention. After intervention, the forelimb and hindlimb grip strength of mice in the high-intensity group was improved, and the swing duration was shortened. However, there were no statistically significant differences in swimming endurance, step length, walking speed and swing speed compared with those before intervention. Compared with the high-intensity group, the forelimb and hindlimb grip strength, swimming endurance, step length and walking speed were significantly improved in the moderate-intensity group. Compared with the control group, the moderate-intensity group showed significant improvements in forelimb and hindlimb grip strength, swimming endurance, walking speed, and swing duration after intervention, and the high-intensity group exhibited improvement only in hindlimb grip strength relative to the control group. Furthermore, after aerobic intervention, the muscle fiber cross-sectional area of mice in the moderate-intensity group was significantly increased with a more uniform and compact arrangement, and the protein and mRNA expression levels of COL Ⅰ, COL Ⅱ and COL Ⅲ were significantly higher than those in the control group and the high-intensity group. Compared with the control group, the mRNA expression levels of COL Ⅰ, COL Ⅱ and COL Ⅲ, as well as the protein expression levels of COL Ⅰ and COL Ⅲ in the high-intensity group were increased (P<0.05 or P<0.01). Conclusions Moderate-intensity aerobic exercise effectively improves limb muscle strength, enhances gait function, promotes the expression of COL Ⅰ, COL Ⅱ, and COL Ⅲ, and ameliorates gastrocnemius morphology in aging mice. High-intensity aerobic exercise is less effective than moderate-intensity exercise in promoting muscle strength and gait function. References | Related Articles | Metrics

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Efficacy of different modalities of inhibitory repetitive transcranial magnetic stimulation for elderly patients with post-stroke aphasia GUO Huaping, CHEN Lina, GOU Lijie 2026, 40 (9):  900-905.  doi: 10.3969/j.issn.1003-9198.2026.09.008 Abstract ( 16 )   PDF (1112KB) ( 29 )   Save Objective To compare the efficacy and safety of low-frequency repetitive transcranial magnetic stimulation (LF-rTMS) and continuous theta burst stimulation (cTBS) in the treatment of elderly patients with post-stroke aphasia(PSA). Methods Fifty elderly patients with PSA were randomly assigned to the LF-rTMS group (n=25) and the cTBS group (n=25) using a random number table. Both groups received conventional speech and language therapy. In addition, the LF-rTMS group received LF-rTMS intervention, while the cTBS group received cTBS intervention. Language function and daily communication ability were assessed before treatment and after 4 weeks of treatment using the Chinese version of the Western Aphasia Battery (WAB) and the Communicative Activities of Daily Living (CADL) scale. During the treatment period, the occurrence of adverse reactions including headache, dizziness, tinnitus and epileptic seizures were recorded. Results After 4 weeks of treatment, both groups showed significant improvements in the scores of spontaneous speech, comprehension, repetition and naming in the Chinese version of WAB, as well as aphasia quotient (AQ) and CADL scores. Compared with the LF-rTMS group, the cTBS group showed significantly greater improvements in comprehension and repetition scores, AQ, and CADL scores after treatment (P<0.05). No serious adverse events were observed in either group. Conclusions Both LF-rTMS and cTBS may improve language function and daily communication ability in older patients with PSA. Compared with LF-rTMS, cTBS may provide additional benefits in comprehension, repetition, AQ, and CADL scores, with good short-term safety and tolerability. References | Related Articles | Metrics

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Construction of a trigger tool for monitoring adverse drug reactions of antitumor drugs in elderly patients based on the Delphi method YAO Min, ZHOU Haihui 2026, 40 (9):  906-912.  doi: 10.3969/j.issn.1003-9198.2026.09.009 Abstract ( 10 )   PDF (1116KB) ( 22 )   Save Objective To establish an adverse drug reaction (ADR) trigger tool for anti-tumor drugs in elderly patients, and to provide a reference for the active monitoring and prevention of ADRs of anti-tumor drugs in elderly patients. Methods Based on the model of the “IHI Global Trigger Tool for Measuring Adverse Events” (referred to as the GTT white paper), referring to the instructions and relevant domestic and foreign literature, using the Delphi expert consultation method, an ADR active monitoring trigger tool for anti-tumor drugs in elderly patients was established. The established trigger tool was used to randomly retrospectively review the elderly patient cases of anti-tumor drug treatment in Nantong Tumor Hospital from January to December, 2023, and the efficacy of the trigger tool was evaluated. Results Through the preliminary preparation, 50 triggers were initially drafted. After two rounds of Delphi expert consultation, 48 trigger items were finally determined, including 25 laboratory indicators, 12 clinical symptoms, 9 antidotes, and 2 intervention measures. Among the 300 reviewed cases, all 48 trigger items had positive triggers, with an ADR detection rate of 67.33%(202/300), and the overall positive predictive value of the trigger tool was 54.01% (829/1535). Conclusions The ADR trigger tool for anti-tumor drug in elderly patients developed in this study is well-designed and verified to be effective,and can provide a reference for medical institutions to conduct active monitoring of anti-tumor drugs in elderly patients and improve clinical medication safety. References | Related Articles | Metrics

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Prevalence of motoric cognitive risk syndrome in hospitalized elderly patients with chronic pain and its influencing factors LUAN Xin, KONG Linshu, XIE Xin, BI Shuhan, ZOU Yinghan 2026, 40 (9):  913-917.  doi: 10.3969/j.issn.1003-9198.2026.09.010 Abstract ( 12 )   PDF (1149KB) ( 21 )   Save Objective To investigate the prevalence of motoric cognitive risk syndrome (MCR) in elderly inpatients with chronic pain and to analyze its influencing factors. Methods A total of 347 elderly inpatients with chronic pain admitted to Liaoning Jinqiu Hospital from October to December in 2025 were selected by convenience sampling. The General Information Questionnaire, the Nutritional Risk Screening 2002 (NRS2002), Numeric Rating Scale (NRS), Hamilton Anxiety Scale (HAMA), Hamilton Depression Scale (HAMD), and Pittsburgh Sleep Quality Index (PSQI) were used to collect relevant clinical data of the patients. Non-parametric test and chi-square test were used to compare the clinical data between the MCR group and the non-MCR group. Logistic regression analysis was conducted to explore the influencing factors of MCR in elderly inpatients with chronic pain. Results The prevalence of MCR in elderly inpatients with chronic pain was 26.22%. There were statistically significant differences between the MCR group and the non-MCR group in terms of age, body mass index (BMI), education level, smoking, drinking, marital status, living and residence mode, number of pain sites, pain treatment methods, and scores of NRS2002, HAMA and PSQI (P<0.01). Logistic regression analysis showed that age, BMI, education level, smoking, living and residence mode, and PSQI score were independent influencing factors of MCR in elderly inpatients with chronic pain (P<0.05). Conclusions The prevalence of MCR in elderly inpatients with chronic pain is relatively high. Age, BMI, education level, smoking, living and residence mode, and PSQI score are independent influencing factors of MCR in elderly inpatients with chronic pain. References | Related Articles | Metrics

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Development and preliminary application of an exercise intervention program for elderly patients with chronic heart failure and frailty LIU Si, TU Hui, XU Yanjuan, GUO Ting, SUN Xinglan, SONG Yujie, XIONG Xiaoyun 2026, 40 (9):  918-923.  doi: 10.3969/j.issn.1003-9198.2026.09.011 Abstract ( 14 )   PDF (1108KB) ( 25 )   Save Objective To develop an intervention program focusing on exercise behavior and exercise content for elderly patients with chronic heart failure (CHF) and frailty, and to preliminarily verify its effectiveness. Methods An exercise intervention program was developed through evidence-based literature review and expert consultation. A single-group pre-post controlled study was conducted among 20 elderly CHF patients with frailty. The frailty level, physical function, quality of life, depression, and exercise self-efficacy before intervention and 1 month and 3 months after intervention were recorded and compared. Results The intervention program consisted of three dimensions—exercise knowledge, exercise self-efficacy, and social support. The 20 patients had a mean age of 71.16±6.94 years, and 11 cases were male. After 1 month of intervention, patients showed no significant improvements in frailty scores, physical function, depression, exercise self-efficacy, and quality of life (P>0.05). After 3 months of intervention, statistically significant differences were observed in patients’ frailty scores, physical function, and depression levels compared with those before the intervention (P<0.05). During the intervention period, 15 patients (75%) completed exercise logs, no exercise-related adverse events occurred, and 2 patients(10%) were rehospitalized within 3 months after discharge. Conclusions This intervention program can improve patients’ exercise awareness and may contribute to improvements in frailty status, physical function, and depression levels, thereby providing a reference for exercise management in elderly patients with CHF and frailty. References | Related Articles | Metrics

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Correlation between MRI imaging parameters and cognitive dysfunction in elderly patients with Parkinson’s disease JIANG Lei, LIU Ying, ZENG Hui 2026, 40 (9):  924-928.  doi: 10.3969/j.issn.1003-9198.2026.09.012 Abstract ( 9 )   PDF (1256KB) ( 22 )   Save Objective To explore the predictive value of magnetic resonance imaging (MRI) parameters for cognitive impairment (CI) in elderly patients with Parkinson’s disease (PD). Methods A retrospective, nested case-control study was conducted. A total of 65 patients with PD complicated with CI, admitted to the Second Affiliated Hospital of Xinjiang Medical University from April 2023 to June 2025, were enrolled as the PD-CI group. Concurrently, 65 PD patients without CI were selected as the PD group. Both groups underwent MRI scans, and apparent diffusion coefficient (ADC) and fractional anisotropy (FA) were recorded. Clinical data of both groups were collected. Multivariate logistic regression analysis was used to identify the influencing factors of CI in elderly PD patients, and receiver operating characteristic (ROC) curve analysis was employed to evaluate the value of MRI imaging parameters in predicting the occurrence of CI in PD patients. Results Compared with the PD group, the PD-CI group had fewer years of education, longer disease duration, and a higher proportion of Hoehn-Yahr (H-Y) stage Ⅲ-Ⅳ (P<0.05). Compared with the PD group, the PD-CI group showed increased ADC levels and decreased FA values in the substantia nigra (P<0.05). Logistic regression analysis showed that long disease duration, H-Y stage Ⅲ-Ⅳ, and high ADC levels were risk factors for CI in elderly PD patients, while high FA was a protective factor. ROC curve analysis results showed that the AUC(95%CI) for predicting CI in elderly PD when combining ADC and FA was 0.894 (0.828-0.941), which was higher than that of ADC and FA alone [0.790(0.709-0.856) and 0.787(0.706-0.853), Z=2.008, 1.990, P<0.05, respectively]. Conclusions ADC and FA of the substantia nigra are influencing factors for the occurrence of CI in elderly PD patients, and the combination of ADC and FA has a good predictive value for the occurrence of CI in elderly patients with PD. References | Related Articles | Metrics

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Construction and validation of an early risk model for chronic pain after hip replacement in the elderly based on machine learning algorithms ZHANG Li, LI Juanqi, ZHANG Cailei, ZHANG Ziru 2026, 40 (9):  929-934.  doi: 10.3969/j.issn.1003-9198.2026.09.013 Abstract ( 11 )   PDF (2217KB) ( 21 )   Save Objective To construct and validate a model for early risk stratification of chronic post-surgical pain (CPSP) after hip replacement in the elderly based on machine learning algorithms. Methods The elderly patients who underwent hip replacement surgery at Tangdu Hospital of Air Force Medical University from May 2023 to June 2025 were enrolled, and were divided into a modeling group (n=425) and a testing group (n=182) in a 7∶3 ratio. LASSO regression was used to screen the characteristic variables of CPSP, and early-risk models were constructed employing various methods: logistic regression, extreme gradient boosting (XGBoost), k-nearest neighbors (KNN), random forest (RF), Light GBM, support vector machine (SVM), and Gaussian Naive Bayes classification (GNB). The models were evaluated using ROC curves, calibration curves, decision curve analysis (DCA), and F1 score, with Shapley additive explanation (SHAP) analysis employed to determine the importance of key variables. Results The incidence rate of CPSP in the modeling group was 20.24% (86/425), compared with 24.18% (44/182) in the testing group. There were statistically significant differences between the modeling group and the testing group in preoperative anxiety, prosthesis type, and physical therapy outcomes (P<0.05). Using LASSO regression, six variable characteristics were identified: alcohol consumption history, time to first postoperative hip movement, surgical duration, Numerical Rate Scale (NRS) score 24 hours after operation, intraoperative blood loss volume, and lower extremity venous thrombosis. Among the seven models developed, the logistic regression model demonstrated the best performance in terms of the area under the curve (AUC), calibration curve, and DCA curve. Using a logistic regression model, the variable factors were ranked by importance as follows: NRS score 24 hours after operation, time to first hip movement after surgery, alcohol consumption history, surgical duration, intraoperative blood loss volume, and lower extremity venous thrombosis. Conclusions The early-stage CPSP risk model for elderly patients receiving hip replacement, constructed using logistic regression, demonstrates strong predictive capability and high interpretability. All model indicators can be obtained during the patient’s hospitalization, facilitating early identification of the patients at high risk for postoperative CPSP. This enables timely implementation of appropriate preventive measures and treatment. References | Related Articles | Metrics

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Evaluation of the effectiveness of mobile pulmonary rehabilitation devices in elderly patients with chronic obstructive pulmonary disease complicated with ischemic heart disease LI Junzhi, DU Yufeng 2026, 40 (9):  935-940.  doi: 10.3969/j.issn.1003-9198.2026.09.014 Abstract ( 11 )   PDF (1100KB) ( 22 )   Save Objective To investigate the clinical efficacy, compliance, and safety of pulmonary rehabilitation based on mobile health devices in the elderly patients with chronic obstructive pulmonary disease (COPD) complicated with ischemic heart disease. Methods A prospective study was carried out in 70 patients with COPD complicated with ischemic heart disease. The patients were randomly divided into a control group (n=35) and a experimental group (n=35) using a random number table. In addition to conventional treatment, the two groups underwent different interventions: the control group received 12 weeks of self-directed pulmonary rehabilitation training, while the experimental group received 12 weeks of pulmonary rehabilitation training using a mobile pulmonary rehabilitation device. The pulmonary function indicators, such as forced expiratory volume in one second (FEV1), forced vital capacity (FVC), FEV1/FVC, percentage of predicted forced expiratory volume in one second (FEV1%pred), and grip strength, 6-minute walk distance (6MWD) of the two groups were observed and compared. The scores of Berg Balance Scale(BBS), COPD Assessment Test (CAT), Seattle Angina Questionnaire (SAQ), Hamilton Anxiety Scale (HAMA), Hamilton Depression Scale (HAMD) were assessed, and training compliance and safety were observed and compared between the two groups before and after the intervention. Results After intervention, the experimental group showed significant improvements in FEV1, FEV1/FVC, FEV1%pred, grip strength, 6MWD, and scores of the BBS, CAT, SAQ, HAMA, and HAMD scales compared to baseline, with all differences being statistically significant (P<0.05). In the control group, grip strength, 6MWD and SAQ scores also exhibited statistically significant improvements post-intervention (P<0.05). The experimental group demonstrated significantly longer 6MWD and higher treatment adherence than those of the control group, with significant difference (P<0.05). No training-related adverse reactions were reported in either group during the study. Conclusions Pulmonary rehabilitation using mobile health devices effectively enhances exercise tolerance and improves treatment adherence in COPD patients with ischemic heart disease. References | Related Articles | Metrics

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Research progress in remission of type 2 diabetes in elderly adults ZHOU Keyi, ZHU Huan, CHE Chenghang, WANG Shuang, SUN Qianqian 2026, 40 (9):  941-946.  doi: 10.3969/j.issn.1003-9198.2026.09.015 Abstract ( 14 )   PDF (1096KB) ( 23 )   Save Traditionally, it is believed that type 2 diabetes mellitus (T2DM) in elderly is an irreversible disease requiring lifelong pharmacotherapy. Nevertheless, with the introduction of the concept of diabetes remission and the steady accumulation of relevant clinical evidence, this conventional perspective is undergoing gradual redefinition. Elderly T2DM refers to diabetes affecting patients aged 65 years and older. For this population, achieving diabetes remission presents greater challenges, which can be attributed to longer disease duration, more pronounced deterioration of islet β-cell function, and the frequent coexistence of multiple complications and comorbidities. This paper systematically reviews the proposal and evolution of its concept, pathophysiological mechanisms, applicable populations and intervention goals. It further summarizes the latest research advances in current clinical intervention strategies and their effects on long-term prognosis, aiming to provide evidence for the clinical management of T2DM in older adults. References | Related Articles | Metrics

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Inflammatory response as a predictor of major adverse cardiovascular events in elderly patients with acute myocardial infarction after percutaneous coronary intervention LIU Haofei, QIN Haidong 2026, 40 (9):  947-951.  doi: 10.3969/j.issn.1003-9198.2026.09.016 Abstract ( 13 )   PDF (1071KB) ( 20 )   Save This review focuses on the risk of major adverse cardiac events (MACE) after percutaneous coronary intervention (PCI) in elderly patients with acute myocardial infarction (AMI), and summarizes the inflammation-related mechanisms, the predictive value of inflammatory biomarkers, and potential therapeutic strategies. Current evidence suggests that inflammation may increase post-PCI MACE risk by impacting plaque stability, thrombosis, and myocardial remodeling. Biomarkers such as high-sensitivity C-reactive protein and the systemic immune-inflammatory index exhibit certain predictive value. However, most existing studies are based on mixed-age populations, and independent evidence in older patients remains insufficient. In addition, integrated predictive models tailored to this population are still lacking. References | Related Articles | Metrics

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Research progress of fecal microbiota transplantation in sarcopenia LI Jiahuan, YUE Ling, WU Quanxin, FU Tao 2026, 40 (9):  952-956.  doi: 10.3969/j.issn.1003-9198.2026.09.017 Abstract ( 19 )   PDF (1070KB) ( 23 )   Save Sarcopenia represents a major health challenge in aging societies, yet effective interventions remain limited. As a core approach for gut microbiota reconstruction, fecal microbiota transplantation (FMT) has achieved groundbreaking progress in sarcopenia in recent years. Current evidence has preliminarily established a causal relationship between gut dysbiosis and sarcopenia. FMT has shown clear efficacy in animal models, and recent clinical studies have also reported positive results. This review systematically summarizes the preclinical and clinical evidence of FMT in sarcopenia, along with its underlying mechanisms. Based on the available evidence, we propose that FMT can improve skeletal muscle mass and function through multiple targets, including the regulation of microbial metabolites, restoration of the intestinal barrier, suppression of chronic inflammation, and enhancement of mitochondrial function. As key functional bacterial strains continue to be identified, FMT is expected to evolve into a precise, standardized targeted intervention, emerging as a novel therapeutic strategy for the prevention and treatment of sarcopenia. References | Related Articles | Metrics

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Retrospective analysis of risk factors for PICC puncture site oozing in elderly patients with hematological diseases LU Rong, LIANG Yuping, YANG Xuemei, HUA Sisi, YAN Jin, WANG Jie, WANG Wei 2026, 40 (9):  957-961.  doi: 10.3969/j.issn.1003-9198.2026.09.018 Abstract ( 14 )   PDF (1084KB) ( 23 )   Save Objective To analyze the risk factors associated with blood oozing at peripherally inserted central catheter (PICC) puncture sites in elderly patients with hematological diseases. Methods We retrospectively investigated clinical data from 238 PICC patients, with multi-dimensional indicators including coagulation, nutrition, inflammation, vascular metabolism, and puncture procedure collected. Univariate and multivariate logistic regression analyses were used to identify the influencing factors of puncture site oozing. The Hosmer-Lemeshow test and receiver operating characteristic (ROC) curve were applied to verify the model’s goodness of fit and predictive performance. Results Univariate analysis showed that age, diabetes mellitus, systolic blood pressure, diastolic blood pressure, fasting blood glucose, glycosylated hemoglobin, total cholesterol, triglyceride, low-density lipoprotein cholesterol (LDL-C), platelet count (PLT), prothrombin time (PT), albumin (Alb), C-reactive protein (CRP), neutrophil-to-lymphocyte ratio (NLR), puncture conditions, skin dilation method were associated with blood oozing (all P<0.05). Multivariate logistic regression analysis confirmed that age ≥ 80 years, PLT≤25×109/L, Alb≤35 g/L, CRP≥10 mg/L, repeated catheterization punctures, systolic blood pressure≥138 mmHg, glycated hemoglobin≥6.0%, and LDL-C≥3.0 mmol/L were independent risk factors for blood oozing. ROC curve analysis showed that the area under the curve (AUC) of the model for predicting puncture site oozing was 0.861; The Hosmer-Lemeshow goodness-of-fit test yielded aχ2 value of 7.136, with P=0.522, indicating excellent goodness of fit and satisfactory predictive performance of the model. Conclusions Comprehensive assessment of high-risk factors related to advanced age, PLT, nutrition, inflammation, and vascular metabolism before catheterization, standardized puncture procedures, improvement of the success rate of one-time puncture, and implementation of individualized puncture site compression nursing can reduce the occurrence of blood oozing. References | Related Articles | Metrics

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Effect of nursing interventions based on the Patient Health Engagement model on the cardiac rehabilitation of elderly patients with acute myocardial infarction after PCI XU Yinyin, WANG Lihua, CHEN Liang, GE Peipei 2026, 40 (9):  962-967.  doi: 10.3969/j.issn.1003-9198.2026.09.019 Abstract ( 13 )   PDF (1110KB) ( 20 )   Save Objective To explore the effect of nursing interventions based on the Patient Health Engagement (PHE) model on cardiac rehabilitation in elderly patients with acute myocardial infarction (AMI) after percutaneous coronary intervention (PCI). Methods Elderly patients diagnosed with AMI and undergoing PCI in Nantong First People’s Hospital from January to June 2024 were enrolled and randomly divided into a control group and an intervention group with 40 cases in each group. The control group received routine rehabilitation care after PCI, while the intervention group received a cardiac rehabilitation nursing intervention based on the PHE model in addition to routine care. The differences in quality of life, anxiety and depression, medication compliance, left ventricular ejection fraction (LVEF) and low-density lipoprotein cholesterol (LDL-C) levels were compared between the two groups at 1, 3, and 6 months after discharge. Results A total of 40 patients in the intervention group and 38 patients in the control group with one dropout and one lost to follow-up were included in the analysis. At 1 month after the intervention, there were significant differences between the two groups in terms of life quality, anxiety scores, treatment compliance, and LDL-C levels (P<0.05). At 3 and 6 months of follow-up, there were significant differences between the two groups in terms of life quality, depression scores, treatment compliance, LVEF and LDL-C levels (P<0.05). Conclusions The cardiac rehabilitation nursing intervention based on the PHE model can improve the psychological status and medication compliance of elderly AMI patients after PCI, and further enhance their postoperative quality of life. References | Related Articles | Metrics