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20 August 2022, Volume 36 Issue 8 Previous Issue    Next Issue

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Evaluation of the effect of alpha-receptor blockers on nocturia in elderly patients with benign prostatic hyperplasia using elastography LI Shao-lei, DING Yan, WU Peng-xi, HU Qiang, RUAN Jun, WANG Yong 2022, 36 (8):  788-790.  doi: 10.3969/j.issn.1003-9198.2022.08.009 Abstract ( 118 )   PDF (1064KB) ( 1623 )   Save Objective To investigate the evaluation value of prostatic tissue elastography stiffness on the efficacy of α-receptor blockers in the treatment of nocturia in the elderly patients with benign prostatic hyperplasia (BPH). Methods The clinical data of 136 BPH patients aged > 60 years old who were treated with α-receptor blockers for nocturia were prospectively collected, including age, body mass index (BMI), International Meniscus Symptom Score (IPSS), IPSS voiding symptom score (IPSSv), IPSS stored symptom scores (IPSSs), and maximum urinary flow rate (Qmax) obtained by urodynamic examination; Total prostate volume (TPV), transitional zone volume (TZV), residual urine volume (PVR), and real-time shear wave elastography (SWE) of prostate transitional zone tissue were measured by transrectal ultrasound to obtain the elastic modulus (Emean). Logistic regression was used to analyze the factors influencing the improvement of nocturia after administration. Results Of the 136 patients, 54 (39.7%) cases showed improvement of nocturia. Compared with the patients without improvement of nocturia, the patients in the improvement group had smaller age, TPV, TZV, Qmax and Emean, with statistically significant differences (P<0.05); While the levels of BMI, IPSS, IPSSv, IPSSs and PVR showed no significant differences between the two groups (P>0.05). Multivariate Logistic analysis showed that age (OR=2.837,95%CI:1.352-5.827) and Emean (OR=4.258,95%CI:2.065-8.710) were the independent factors for improvement of nocturia in BPH patients. The area under the receiver operating characteristic curve of Emean for predicting the improvement of nocturia after medication in the elderly patients with BPH was 0.747 (95% CI: 0.628-0.852), with an optimal cut-off point of 38.4 kPa, and the sensitivity and specificity was 74.14% and 70.68%, respectively. Conclusions Prostate tissue elastography stiffness can predict the therapeutic effect of α-receptor blockers in the treatment of BPH nocturia. References | Related Articles | Metrics

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Effect of balance and coordination intensive training on the early reconstruction of lower limb motor function after hip replacement in elderly FENG Yu, YAO Na, LI Peng-cheng, CHEN Hong-bo, SONG Yan-ping, HUANG Li, CHEN Qi-gang 2022, 36 (8):  791-795.  doi: 10.3969/j.issn.1003-9198.2022.08.010 Abstract ( 128 )   PDF (1045KB) ( 1253 )   Save Objective To explore the effect of E-LINK balance training device on the early recovery and reconstruction of lower limb motor function in the elderly patients receiving total hip replacement. Methods Seventy-two elderly patients receiving total hip arthroplasty in our hospital from August 2020 to July 2021 were selected as the research objects, and they were randomly divided into observation group and control group with 36 cases in each group. The control group was given routine rehabilitation training intervention, and the observation group was given balance and coordination intensive training using E-LINK balance function training instrument on the basis of the control group. The intervention lasted for 8 weeks. The recovery of hip function, balance state, posture control and gait function were compared between the two groups before intervention and 4, 8 weeks after intervention. Results Before the intervention, there were no significant differences in Berg Balance Scale (BBS) score, Harris Hip Score (HHS), Timed Up and Go Test (TUGT) time and peak value of continuous biaxial pressure plate between the two groups (P<0.05). After 4 and 8 weeks of intervention, the TUGT time of the two groups decreased, and the BBS score, HHS score and the peak value of the E-LINK continuous biaxial pressure plate increased significantly, especially in the observation group(P<0.05). Conclusions E-LINK balance training instrument can promote the recovery of hip function in the elderly patients after hip replacement, and strengthen the balance and coordination ability, and accelerate the reconstruction of lower limb walking and motor function. References | Related Articles | Metrics

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Epidemiological characteristics of hypertension combined with diabetes among the elderly people in Nanjing, China YAO Zhu-ling, WANG Zhi-yong, XIONG Ya-qing, XU Fei 2022, 36 (8):  796-800.  doi: 10.3969/j.issn.1003-9198.2022.08.011 Abstract ( 151 )   PDF (1047KB) ( 1738 )   Save Objective To investigate the prevalence and distribution characteristics of hypertension combined with diabetes among the elderly people in Nanjing. Methods From April to October 2017, 20 883 regular residents aged ≥60 years old were selected in Nanjing by multistage stratified cluster sampling method, and they were investigated by general information questionnaire, physical examination and laboratory examination. The outcome variables were diagnosed and newly-identified hypertension and diabetes. The differences in the prevalence of hypertension and diabetes among the different sub-populations were analyzed. Results The prevalence of hypertension and diabetes in the elderly population of Nanjing was 59.0% (95%CI:0.584-0.597) and 28.7% (95%CI:0.281-0.293), respectively; While the prevalence of comorbidity of hypertension and diabetes was 20.7% (95%CI:0.202-0.213). There were significant differences in the prevalence of comorbidity of hypertension and diabetes among the elderly with different age, gender, place of residence, body mass index (BMI), education level, ethnicity, physical activity situation and medical insurance types (P<0.05). Among the newly discovered patients with the comorbidity of hypertension and diabetes, there were significant difference in the prevalence among the elderly with different place of residence, BMI and medical insurance types (P<0.05). Conclusions The prevalence of hypertension, diabetes and their co-morbidities are high in the elderly population of Nanjing. We should pay attention to the elderly who live in urban, being overweight or obese and using employee medical insurance. References | Related Articles | Metrics

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Effect of thyroid hormones on carotid artery intima-media thickness in elderly patients with chronic heart failure WANG Bo, MA Yun-fei, WANG Ke 2022, 36 (8):  801-804.  doi: 10.3969/j.issn.1003-9198.2022.08.012 Abstract ( 124 )   PDF (1034KB) ( 1746 )   Save Objective To analyze the effect of thyroid hormones on carotid intima-media thickness (IMT) in the elderly patients with chronic heart failure. Methods A retrospective analysis was performed on 108 elderly patients with chronic heart failure admitted to our hospital from June 2017 to June 2021. According to the level of IMT, the patients were divided into the thickening group (IMT≥1.0 mm, n=46) and the non-thickening group (IMT<1.0 mm, n=62). The general data and clinical data of the two groups were compared, and the influencing factors of IMT in the elderly patients with chronic heart failure were analyzed by Logistic regression. At the same time, the patients were divided into low group (TSH<1.00 mIU/L, n=26), medium group (1.00 mIU/L≤TSH≤2.74 mIU/L, n=55) and high group (TSH > 2.74 mIU/L, n=27) according to the quartile level of TSH. The level of IMT and carotid artery plaque number of the patients with different TSH levels were compared. Results Compared with the non-thickening group, the patients in the thickening group were older, and had longer course of disease, lower level of free thyroxine acid, and higher levels of TSH, C-reactive protein (CRP), total cholesterol (TC) and apolipoprotein A1, with statistical significance (P<0.05). Logistic regression analysis showed that aged ≥70 years old, TSH≥3 mIU/L, CRP≥3.5 mmol/L and TC≥4.5 mmol/L were the independent risk factors of IMT thickening in the elderly patients with chronic heart failure. Compared with the high group, the level of IMT in the low group and the middle group were significantly decreased (P<0.05). There was no significant difference in carotid artery plaque number among the patients with different TSH levels (P>0.05). Conclusions The development of IMT might be correlated with age, TSH, CRP and TC in the elderly patients with chronic heart failure. References | Related Articles | Metrics

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Value of cortical bone thickness and gray value measured by X-ray in predicting the risk of hip fragility fracture in elderly patients with osteoporosis XU Qin, WANG Li-ming, SHA Wei-ping, YAN Fei, HUANG Qun, ZHOU Zhi-ping 2022, 36 (8):  805-808.  doi: 10.3969/j.issn.1003-9198.2022.08.013 Abstract ( 135 )   PDF (1029KB) ( 1865 )   Save Objective To investigate the value of cortical bone thickness and gray value measured by X-ray in predicting the risk of hip fragility fracture of the elderly patients with osteoporosis. Methods The clinical data of 82 elderly patients with osteoporosis who underwent X-ray pelvic examination in our hospital from March 2018 to February 2021 were retrospectively analyzed. The incidence of hip fragility fracture of the patients was recorded, and the clinical data of the fracture group and the non-fracture group were compared. The risk factors of hip fragility fracture in the elderly patients with osteoporosis were analyzed by Multivariate Logistic regression, and the receiver operating characteristic (ROC) curve was drawn to analyze the value of cortical bone thickness and gray value measured by X-ray in predicting the risk of hip fragility fracture in the elderly patients with osteoporosis. Results Among the 82 patients, 28 presented with hip fragility fracture, and the incidence rate was 34.15%. The bone mineral density of L2 vertebra and greater trochanter, the cortical bone thickness of the upper and the lower of lesser trochanter, and the gray value of X-ray scanning in the fracture group were lower than those in the non-fracture group (P<0.05). Multivariate Logistic regression analysis showed that the cortical bone thickness of the upper of lesser trochanter (OR=3.374, 95%CI: 1.853-8.429, P=0.012) and gray value of X-ray scanning (OR=3.133, 95%CI:1.506-6.475, P=0.023) were the risk factors for hip fragility fracture in the elderly patients with osteoporosis. ROC curve analysis showed that the area under the curve (AUC) of the cortical bone thickness of the upper of lesser trochanter combined with the gray value of X-ray scanning in predicting hip fragility fracture in the elderly patients with osteoporosis was 0.856, which was higher than that of the two indexes separately (Z=1.976, P=0.048; Z=2.202, P=0.028). Conclusions The cortical bone thickness of the upper of lesser trochanter and the gray value of X-ray scanning can predict the risk of hip fragility fractures in the elderly patients with osteoporosis, and the combination of the two indexes has a higher predictive efficiency. References | Related Articles | Metrics

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Analysis of the influencing factors of nutritional status in elderly patients with stroke during convalescence by comprehensive geriatric assessment WANG Xiao-jiao, WANG Ning, CUI Hong, YE Tong, GUO Jia-yi, WANG Xiao-ming, JIA Xin 2022, 36 (8):  809-812.  doi: 10.3969/j.issn.1003-9198.2022.08.014 Abstract ( 120 )   PDF (1022KB) ( 1984 )   Save Objective To analyze the influencing factors of the nutritional status in the elderly patients with stroke during convalescence by comprehensive geriatric assessment (CGA). Methods A total of 114 patients with stroke ( age≥60 years old, the length of stay>24 h) in our hospital from August 2019 to April 2021 were selected, and were divided into 3 groups: the old aged group (aged ≥80 years old, n=38), the middle aged group ( aged 70-79 years old, n=40) and the young aged group ( aged 60-69 years old, n=36). The nutritional status of the patients were assessed by mini-nutritional assessment (MNA). All the patients received CGA. The influencing factors of malnutrition in the elderly patients with stroke during convalescent were analyzed by multivariate Logistic regression. Results Among the 114 patients, 34 patients presented with malnutrition risk (29.82%) and 32 patients with malnutrition (28.07%). There was significant difference in the incidence of malnutrition between the old aged group and the young aged group (P< 0.05). Multivariate Logistic regression analysis showed that age, the course of stroke, activities of daily living, dysphagia, tooth loss or aging affecting eating, psychological disorders, cognitive impairment and offspring looking after their parents were the independent influencing factors of malnutrition in the elderly patients with stroke during convalescence. Conclusions CGA can more comprehensively evaluate the influencing factors of nutritional status in the elderly patients with stroke during convalescence, which is helpful for the development of individualized management measures. References | Related Articles | Metrics

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Relationship between sleep disorder and social frailty among community-dwelling elderly SONG Ge, WANG Ying, GAO Huan-ling, CHEN Ling, YANG Yu-lin 2022, 36 (8):  813-817.  doi: 10.3969/j.issn.1003-9198.2022.08.015 Abstract ( 147 )   PDF (1054KB) ( 1895 )   Save Objective To explore the relationship between sleep disorder and social frailty of the elderly in community, so as to provide reference for prevention and improvement of social frailty in the elderly. Methods The general data questionnaire, Social Frailty Assessing Tool and Pittsburgh Sleep Quality Index (PSQI) scale were surveyed through face-to-face interview with participants at their houses. And the relationship between sleep disorder and social frailty was analyzed. Results A total of 516 valid questionnaires were finally included in this research. The incidence rate of sleep disorder was 42.05%, and the incidence rate of social frailty was 12.79% in the elderly. There were significant differences in the number of chronic diseases, physical exercise, intellectual activities and sleep disorders between the social frailty group and the non-social frailty group (P<0.05 or P＜0.01). Logistic regression analysis showed that sleep disorder was an independent risk factor of social frailty (OR=1.904,95%CI: 1.095-3.311, P=0.022).There were significant differences in the total score of social frailty and the score of each item between the sleep disorder group and the non-sleep disorder group (P<0.05 or P＜0.01). Correlation analysis results showed that the total score of PSQI was moderately positively correlated with social frailty (r=0.429, P<0.001), and the scores of 7 factors of PSQI were positively correlated with social frailty (P<0.05). Conclusions The incidence rates of sleep disorder and social frailty are high in the elderly. Sleep disorder is an independent risk factor of social frailty in the elderly in the community. It is necessary to pay more attention to the sleep quality of the elderly, and to prevent and intervene the sleep disorder of the elderly from multiple dimensions, so as to further improve the health level and quality of life of the elderly population. References | Related Articles | Metrics

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Effect of lipoprotein(a) on perioperative myocardial injury in elderly patients with coronary heart disease after PCI SUN Jun-xiang, CHEN Yan-chun, YIN Yun-jie, ZHUANG Qian, WEI Peng-fei, XU Liang, YANG Song 2022, 36 (8):  818-821.  doi: 10.3969/j.issn.1003-9198.2022.08.016 Abstract ( 121 )   PDF (1038KB) ( 1782 )   Save Objective To explore the relationship between lipoprotein(a) [Lp(a)] and perioperative myocardial injury(PMI) in the elderly patients with coronary heart disease(CHD). Methods A total of 200 elderly patients with CHD who received PCI in Yixing People's Hospital from January 2020 to March 2021 were enrolled in this study. According to the level of troponin T (cTnT), the patients were divided into the observation group with elevated cTnT level (n=106) and the control group with normal cTnT level (n=94), and the differences in all the clinical data between the two groups were analyzed. According to SYNTAX score, the patients were divided into low score group (0-22), middle score group (23-32) and high score group (≥33). The level of Lp(a) was detected and compared among all groups. Results The levels of age and Lp(a), the numbers of the stents and the total length of the stents were significant higher in the observation group than those in the control group(P<0.05). According to SYNTAX score, the level of Lp(a) in the low score group, the middle score group and the high score group was 168.29±28.97 mg/L, 294.72±28.25 mg/L and 465.29±48.62 mg/L, respectively, with significant differences among the three groups (P<0.05). The Logistic regression analysis showed that age(OR=1.106, 95%CI: 1.044-1.171), Lp(a)(OR=2.291, 95%CI: 1.150-4.562), total length of the stents(OR=1.015, 95%CI: 1.004-1.027)were the independent influencing factors of PMI. Conclusions The preoperative high level of Lp(a) is a risk factor of PMI after PCI in the elderly patients with CHD. Lp(a) has a positive relationship with the severity of coronary lesions. References | Related Articles | Metrics

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Nutrition status and the risk factors in the elderly YU A-cui, CHEN Xi, YANG Meng-na, SONG Xiao-ming, LI Hao, CI Li-ya 2022, 36 (8):  822-826.  doi: 10.3969/j.issn.1003-9198.2022.08.017 Abstract ( 156 )   PDF (1099KB) ( 2006 )   Save Objective To assess the nutritional status in the elderly and to analyze the risk factors affecting the nutrition. Methods Through cluster sampling methods, 262,226 elderly people aged over 65 years old in Yantai City from December 2019 to March 2020 were selected and underwent Mini-Nutritional Assessment Short-Form (MNA-SF) assessment. Multivariate Logistic regression was used to analyze the risk factors influencing malnutrition. Results The results showed that among the 219 222 validly surveyed elderly people in Yantai, 24 489 (11.2%) were assessed to be at risk of malnutrition and 1589 (0.7%) were assessed as malnutrition. Compared with the normal nutrition group, there were statistical differences in age, education level, place of residence, marital status, pension mode, polypharmacy, self-care ability, cognitive function, risk of aspiration, risk of falling, risk of pressure ulcer, and depressive state in the risk of malnutrition and malnutrition group. Multivariate Logistic regression analysis showed that older age, urban residence, institutional care, decline in self-care ability, cognitive dysfunction, risk of aspiration, risk of falling, risk of pressure ulcers, depression and polypharmacy were the risk factors of malnutrition (P＜0.01). Higher education level and being married were the protective factors of malnutrition in the elderly (P＜0.01). Conclusions The incidence rate of malnutrition in the elderly is influenced by lots of factors. Attention should be paid to the assessment of the nutritional status, and targeted interventions should be formulated to improve their nutritional status. References | Related Articles | Metrics

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Relationship between serum soluble triggering receptor expressed on myeloid cells-1 and the severity and prognosis of elderly patients with acute ischemic stroke LIN Qiao-mao, LI Kuo, XIANG Ning, WANG Hai-yan 2022, 36 (8):  827-832.  doi: 10.3969/j.issn.1003-9198.2022.08.018 Abstract ( 116 )   PDF (1075KB) ( 2016 )   Save Objective To investigate the relationship between the serum level of soluble triggering receptor expressed on myeloid cells-1 (sTREM-1) and the severity and prognosis of the elderly patients with acute ischemic stroke (AIS). Methods A total of 98 elderly patients with AIS were selected as the AIS group and were divided into a mild deficit group (n=28), a moderate deficit group (n=29) and a severe deficit group (n=41) according to the score of National Institutes of Health Stroke Scale (NIHSS) at admission, and were divided into a poor prognosis group (n=38) and a good prognosis group (n=60) according to the score of modified Rankin Scale (mRS) after 6 months. And another 45 elderly healthy individuals were selected as the control group during the same period. The serum levels of sTREM-1, interleukin-6 (IL-6), tumor necrosis factor-α (TNF-α) and S100B were measured by enzyme linked immunosorbent assay. Pearson or Spearman correlation was used to analyze the correlations of serum sTREM-1 with IL-6, TNF-α, S100B, NIHSS and mRS scores in AIS patients. The influencing factors of poor prognosis of AIS were analyzed by Logistic regression. The predictive value of sTREM-1 for poor prognosis was analyzed using receiver operator characteristic (ROC) curve. Results The serum levels of sTREM-1, IL-6, TNF-α and S100B were increased in the AIS group compared with the control group (all P＜0.01). The serum levels of sTREM-1, IL-6, TNF-α and S100B were sequentially increased in the mild, moderate and severe deficit groups (all P＜0.01). The serum level of sTREM-1 in the patients with AIS was positively correlated with the levels of IL-6, TNF-α, S100B and NIHSS, mRS scores (r=0.764, 0.816, 0.823, 0.733, 0.626, all P＜0.01). Single factor analysis showed that the level of serum HDL-C was lower, the levels of LDL-C, sTREM-1, IL-6, TNF-α, S100B and NIHSS score were higher,the time from onset to admission was longer in the poor prognosis group than those in the good prognosis group (all P<0.05). Multivariate Logistic regression analysis showed that IL-6 (OR=1.037, 95%CI: 1.004-1.071), TNF-α (OR=1.046, 95%CI: 1.018-1.074), S100B (OR=1.139, 95%CI: 1.035-1.254), NIHSS score (OR=1.347, 95%CI: 1.085-1.674), sTREM-1 (OR=2.172, 95%CI: 1.098-4.296) were the independent risk factors of poor prognosis in the elderly patients with AIS. The area under ROC curve, sensitivity and specificity of serum sTREM-1 level to predict poor prognosis in the patients with AIS were 0.816, 94.74% and 61.67% respectively. Conclusions The increase of serum sTREM-1 in the elderly AIS patients is closely related to the severity and prognosis of AIS, and can be used as a predictor for poor prognosis. References | Related Articles | Metrics

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Effects of varying ankle-foot orthosis on balance and gait in elderly hemiplegic patients with stroke SU Pan-pan, MENG Dian-huai 2022, 36 (8):  833-837.  doi: 10.3969/j.issn.1003-9198.2022.08.019 Abstract ( 129 )   PDF (1053KB) ( 1594 )   Save Objective To investigate the effects of bare foot, soft plastic ankle-foot orthosis (sAFO) and hard plastic ankle-foot orthosis (hAFO) on balance and gait in the elderly hemiplegic patients with stroke. Methods A total of fifty-two elderly hemiplegic patients with stroke (38 male, 14 female) were enrolled in this study. Under the two status of opening and closing eyes respectively, the Pro-Kin balance evaluation training instrument was used to evaluate the static standing balance function under three conditions of bare foot, sAFO and hAFO. The feet stood at the optimal distance under each condition, and the main measurement parameters including the standard deviation of longitudinal swing (SDoLS), the standard deviation of horizontal swing (SDoHS), mean longitudinal velocity (MLV), mean horizontal velocity (MHV), the ellipse area of motion (EAM) and the length of motion (LM) were recorded. The Tinetti Performance-Oriented Mobility Assessment (POMA) was used to evaluate the dynamic balance and gait. Results The optimum distance between feet of bare foot, sAFO and hAFO was (15.46±4.65) cm, (17.87±5.5) cm, (18.43±5.45) cm respectively. In the state of opening the eyes, MHV, EAM, LM of standing with the sAFO condition were significantly lower than those with the bare-foot condition (P<0.05); In the state of closing the eyes, SDoHS, MHV, EAM, LM of standing with the sAFO condition were significantly lower than those with the bare-foot condition (P<0.05); In the state of opening the eyes, SDoLS, SDoHS, MHV,EAM, LM of standing with the hAFO condition were significantly lower than those with the bare-foot condition (P<0.05); In the state of closing the eyes, SDoLS, SDoHS, MHV, EAM, LM of standing with the hAFO condition were significantly lower than those with the bare-foot condition (P<0.05); In the state of opening the eyes, SDoHS of standing with hAFO condition was significantly lower than that with sAFO condition (P<0.05); In the state of closing the eyes, SDoLS of standing with hAFO condition was significantly lower than that with sAFO condition (P<0.05). The scores of Tinetti POMA, POMA-B and POMA-G with the sAFO condition were significantly higher than those with the bare-foot condition (P<0.05); The scores of Tinetti POMA and POMA-B with the hAFO condition were significantly higher than those of the bare-foot condition (P<0.05); The scores of Tinetti POMA and POMA-G with the sAFO condition were significantly higher than those with the hAFO condition (P<0.05). Conclusions Both sAFO and hAFO can improve the static and dynamic balance function of the elderly hemiplegic patients with stroke, and sAFO is more effective in improving gait function. References | Related Articles | Metrics

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Risk factors of postoperative delirium in elderly patients undergoing hip arthroplasty under general anesthesia LI Nan, JI Wei-wei, LIU Wei, CHEN Xue 2022, 36 (8):  838-841.  doi: 10.3969/j.issn.1003-9198.2022.08.020 Abstract ( 147 )   PDF (1025KB) ( 1466 )   Save Objective To explore the incidence and risk factors of postoperative delirium in the elderly patients undergoing hip arthroplasty under general anesthesia. Methods A total of 196 elderly patients who underwent hip arthroplasty in our hospital under general anesthesia from January 2018 to June 2021 were enrolled in this study. The incidence and risk factors of postoperative delirium were analyzed by univariate and multivariate Logistic regression. Results Among 196 elderly patients undergoing hip arthroplasty under general anesthesia, 66 presented with postoperative delirium, with an incidence rate of 33.67%.There were significant differences in age, ASA grade > grade Ⅱ, intraoperative bleeding > 300 mL, operation time >120 min, preoperative hypoproteinemia, preoperative anxiety, postoperative VAS score >3, P dimension score, N dimension score and E dimension score between delirium group and non-delirium group (P<0.05). Multivariate Logistic regression analysis showed that age>75 years old, intraoperative bleeding >300 mL, preoperative hypoproteinemia, preoperative anxiety, postoperative VAS score >3, N dimension score ≥56.8 and E dimension score ≥56.8 were the risk factors of postoperative delirium in the elderly patients undergoing hip arthroplasty under general anesthesia. Conclusions The incidence of postoperative delirium in the elderly patients undergoing hip arthroplasty under general anesthesia is high. Extroversion and neuroticism are the risk factors of postoperative delirium in the patients undergoing hip arthroplasty. We should strengthen psychological counseling and intervention for relevant patients. References | Related Articles | Metrics

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Relationship between frailty and cognitive function of community-dwelling elderly: the mediating mechanism of resilience LIU Hong, LI Yan-zhang, ZHANG Hui, XIONG Mei, ZHANG Yu-ping 2022, 36 (8):  842-845.  doi: 10.3969/j.issn.1003-9198.2022.08.021 Abstract ( 143 )   PDF (1085KB) ( 2027 )   Save Objective To explore the relationship between frailty and cognitive function of community-dwelling elderly, and to analyze the mediating effect of resilience between frailty and cognitive function. Methods A total of 827 community-dwelling elderly were investigated by Tilburg Frailty Indicator(TFI), 10-item Connor-Davidson Resilience Scale(CD-RISC-10), Mini-Mental State Examination (MMSE) and self-made general condition scale. Results The incidence rate of frailty and cognitive decline among community-dwelling elderly was 30.11% and 21.04%, respectively. Frailty was significantly negatively correlated with resilience(r=-0.45, P<0.01) and cognitive function(r=-0.34, P<0.01), and resilience was significantly positively correlated with cognitive function (r=0.39, P<0.01). The model fitting results showed that resilience played a mediating role in the relationship between frailty and cognitive function(β=-0.13, P<0.01). Conclusions Frailty has a direct predictive effect on the cognitive function of community-dwelling elderly, and it is moderated by the mediating effect of resilience. Reducing the frailty degree of the elderly and improving the level of resilience might reduce the incidence of cognitive decline and promote the healthy aging of the elderly. References | Related Articles | Metrics

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Clinicopathological features and prognosis of intermediate-risk gastric stromal tumors in the elderly REN Xi-mei, YANG Jin-ping, NI Mu-han, LIU Jin-yan, ZHENG Chang, WANG Ya-nan, WANG Lei, XU Gui-fang 2022, 36 (8):  846-849.  doi: 10.3969/j.issn.1003-9198.2022.08.022 Abstract ( 154 )   PDF (1032KB) ( 1081 )   Save Objective To investigate the clinicopathological features and long-term prognosis of the elderly patients with intermediate-risk gastric stromal tumors. Methods A total of 62 elderly patients with intermediate-risk gastric stromal tumors from December 2009 to July 2020 were analyzed retrospectively. The clinical features, pathological data, and long-term prognosis were collected and analyzed. Results Among the 62 patients, there were an average age of 67.7±5.3 years old. The major symptom was abdominal discomfort (48.4%), and 38.7% of the cases were found by physical examination. The main lesion sites were the upper part (46.8%) and the middle part (46.8%) of the stomach. The average diameter of the tumor was 5.4±2.3 cm. The mitotic number was ≤ 5/50HPF in 40 cases (64.5%), and 49 patients were treated with surgery and 13 patients treated with endoscopic resection. There were 23 and 3 patients receiving imatinib in the surgical group and endoscopic group, respectively. During a median follow-up of 53 months, 2 cases of non-disease-specific death occurred in the surgical group. None of the 62 patients presented with recurrence or metastasis, with an overall survival rate of 96.3% and a disease-specific survival rate of 100%. Conclusions The prognosis of the elderly patients with intermediate-risk gastric stromal tumors is good, regardless of whether they are treated with imatinib or not. Endoscopic treatment for moderate-risk gastric stromal tumors in the elderly patients may be a safe and effective way. References | Related Articles | Metrics