Abstract:

ted to Medical College Nanjing University, Nanjing 210008, China
【Ａｂｓｔｒａｃｔ】　ＯｂｊｅｃｔｉｖｅTo investigate the efficacy of the anticoagulation for acute exacerbation of chronic obstructive pulmonary disease(AECOPD) with coexisting suspected acute pulmonary embolism(PE).ＭｅｔｈｏｄｓFortytwo inpatients with severe AECOPD with a positive Ddimer assay were divided into group A (a value of PaO2 was normal) and group B(hypoxia). The two groups were randomly redistributed into anticoagulation subgroups (A1 and B1) and nonanticoagulation subgroups (A2 and B2). The consequences of the management were surveyed and assessed.ＲｅｓｕｌｔｓCompared with  B2 subgroup, there were significant differences in dyspnea, PaO2,Ddimer(P＜005) in B1 subgroup.ＣｏｎｃｌｕｓｉｏｎｓAnticoagulation should immedidately be given to patients with severe AECOPD who have risk factors for venous thromboembolism or high probability for PE.