临床辅助决策系统降低老年多重用药与潜在不适当用药效果的系统评价

doi:10.3969/j.issn.1003-9198.2023.06.007

Abstract

Abstract: Objective To systematically evaluate the intervention effect of clinical decision support system (CDSS) on potentially inappropriate medication (PIM) and polypharmacy in the elderly patients. Methods The database searches were carried out through PubMed,Embase and Web of Science to collect the randomized controlled trials (RCTs) data about the intervention effect of CDSS on polypharmacy and PIM in the elderly patients until April 2022. Two reviewers screened the literatures, extracted data and assessed the quality independently. Results A total of 14 studies involving 641 143 patients were included. There were 10 studies involving 629 599 patients analyzing the intervention effect of CDSS on PIM and 4 studies involving 11 544 patients analyzing the intervention effect of CDSS on polypharmacy. A meta-analysis was not possible due to the significant heterogeneity among the systems used and the measurement outcomes. In general, CDSS could reduce the prevalence of PIM in the elderly and further data were needed on the effects of CDSS on polypharmacy. Conclusions The application of CDSS has potential to reduce PIM in the elderly patients.

Key words: potentially inappropriate medication, polypharmacy, clinical decision support system, systematic review

CLC Number:

R 181.35

HE Cui-lin, TIAN Fang-yuan, WU Jin-hui. Using clinical decision support system to reduce potentially inappropriate medication and polypharmacy in elderly patients: a systematic review[J]. Practical Geriatrics, 2023, 37(6): 564-568.

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Using clinical decision support system to reduce potentially inappropriate medication and polypharmacy in elderly patients: a systematic review

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