Abstract: Objective To observe the effect of phacoemulsification cataract extraction combined with 23G vitrectomy on the stability of the tear film. Methods A total of 120 patients with vitreoretinal disease in our hospital from 2017 to 2019 were enrolled, and they were divided into two groups according to the surgical method: 60 patients (60 eyes)were treated with 23G vitrectomy (control group) and 60 patients (60 eyes)were treated with phacoemulsification cataract extraction combined with 23G vitrectomy (observation group). All the patients were examined by the Schirmer I test (SⅠt), break-up time (BUT) and cornea fluorescein staining (CFS) before operation, 7 days, 30 days and 90 days after operation. Results There were no statistical differences in the preoperatively examination results of SⅠt, BUT or CFS between the two groups (P>0.05). The BUT of both groups was shortened significantly 7 days and 30 days after operation (P<0.05), the score of CFS and the value of tear secretion in both groups were significantly increased 7 days after operation (P<0.05), and the changes of the above indexes in the observation group were more significant than those in the control group (P<0.05). 90 days after operation, there was no significant difference in the value of tear secretion, CFS score and BUT between the two groups (P>0.05), and they all recovered to the preoperative level. Conclusions Compared with vitrectomy, the effect of phacoemulsification cataract extraction combined with 23G vitrectomy on tear film stability 7 days after operation is more obvious, and the related indexes can recover to the preoperative level in 90 days after operation.

Key words: cataract phacoemulsification, vitrectomy, stability of tear film