Abstract:

ＯｂｊｅｃｔｉｖｅTo evaluate the safety and variation of blood potassium during argentine stimulation test in patients with type 2 diabetes mellitus(T2DM).ＭｅｔｈｏｄｓThe argentine stimulation test was performed in 70 individuals with T2DM. The feelings after being injected with argentine of each patient were recorded. Plasma glucose(PG), insulin and potassium levels were measured.ＲｅｓｕｌｔｓThe most common feelings included metallic taste, tongue numbness and burning sensation, all of which were tolerable. Plasma glucose increased with no stalistical significance（ΔPG＝0.46±1.13 mmol／L，P＞005）, while insulin significantly increased（ΔINS=128±073 mmol／L，P＜005）, after injection of argentine. Blood potassium significantly decreased after injection of argentine[ΔK=-(033±025)mmol／L，P＜001]. ΔK  was positively correlated to fasting potassium level.ＣｏｎｃｌｕｓｉｏｎｓIt is safe to conduct argentine stimulation test in patients with T2DM, especially in those with higher blood glucose level.

Key words: diabetes, argentine stimulation test, blood glucose, blood potassium