Abstract:

ＯｂｊｅｃｔｉｖｅTo investigate the clinical efficacy of glargine in elderly type 2 diabetic patients during the perioperative period. ＭｅｔｈｏｄｓSixtyone cases of perioperative elderly patients with type 2 diabetes were divided into three groups. One group receiving subcutaneous injection of glargine, another group receiving insulin pump and basic dose of insulin, still another group receiving intravenous insulin infusion. Blood glucose controlled time, the average blood glucose, blood glucose fluctuations, insulin dosage per day, the incidence of hypoglycemia and the average daily cost were compared among three groups after treatment.ＲｅｓｕｌｔｓThe blood glucose controlled time, the average blood glucose, insulin dosage per day, the incidence of hypoglycemia and blood glucose fluctuations in glargine group had no significant difference compared with insulin pumps group (P＞005), but were significantly lower than those in the intravenous insulin infusion group (P＜001). The average daily cost in glargine group was significantly lower than that in insulin pumps group (P＜001). ＣｏｎｃｌｕｓｉｏｎｓThe efficacy and the safety of glargine treatment applied in elderly patients with type 2 diabetes during the perioperative period are similar to that of insulin pumps treatment, but the cost of treatment is significantly lower than that of insulin pump.

Key words: type 2 diabetes, aged, perioperation, glargine, insulin pump