Abstract:

ＯｂｊｅｃｔｉｖｅTo observe the curative effects of fluvastatin in treatment of mild and moderate Alzheimers disease.Ｍｅｔｈｏｄｓ120 patients with mild and moderate Alzheimers disease were randomly divided into the control group and the study  group. The control group received conventional therapy,while the study group was administrated orally with 40 mg of fluvastatin every evening additionally. The levels of TC,TG,LDLC,HDLC as well as the scores of MMSE,CDR and ADL were compared between the two groups at week 4 and week 12 after treatment, respectively.ＲｅｓｕｌｔｓThe improvements of TC,TG,LDLC,HDLC and the scores of MMSE,CDR,QOL and ADL were significantly greater in the study group than those in the control group (P<005).ＣｏｎｃｌｕｓｉｏｎｓFluvastatin can postpone the progress of mild and moderate Alzheimers disease, as well as lowering serum lipids.