实用老年医学

实用老年医学 ›› 2010, Vol. 24 ›› Issue (2): 141-143.

• 论著 • 上一篇    下一篇

高浓度氯化钾微泵注射在老年重度低钾血症的应用

  

  1. 江苏省老年医院急诊科（郑娟，李晓虹，朱学云,陈俊）；210006江苏省南京市，南京市第一医院ICU(王红霞)
  • 出版日期:2010-04-20 发布日期:2010-03-10

Application of microinjection pump in high concentration potassium chloride infusion in the aged with severe hypokalemia

  • Online:2010-04-20 Published:2010-03-10

被引次数

29

摘要：

目的探索微量泵经中心静脉输入高浓度氯化钾在老年重度低钾血症治疗中的安全性及有效性。方法42例老年重度低钾血症患者随机分入试验组及对照组,试验组以静脉微泵经中心静脉恒速输入6%KCl溶液;对照组输入03%氯化钾溶液，补钾速度均为1～15 g/h,观察2组在血钾变化、临床症状缓解速度、不良反应及补钾总量上的差异。结果在血钾升至30 mmol/L时,试验组耗时（395±257） h,输入氯化钾（405±188） g,为补钾而输入的液体为（115±25） ml,对照组分别为（723±445） h、（836±378） g、（2054±1250） ml;缓解恶性心律失常所需时间试验组为（122±035） h,对照组为（255±086） h；以上各指标2组间比较，差异均有统计学意义（P＜005）。血钾完全正常时，试验组共补充氯化钾（355±123）g,对照组（416±155） g,2组比较无统计学差异（P＞005）。结论微量泵经中心静脉输入高浓度氯化钾在老年重度低钾血症的治疗中安全、有效。

关键词: 低钾血症, 老年人, 微量泵, 中心静脉

Abstract:


【Ａｂｓｔｒａｃｔ】　ＯｂｊｅｃｔｉｖｅTo research the safety and efficacy of high concentration potassium chloride infusion with micropump through central vein in aged patients with severe hypokalemia.ＭｅｔｈｏｄｓFortytwo elderly patients with severe hypokalemia were randomly divided into two groups: experimental group and control group.Patients in the experimental group were treated with micropump infusion of 6% KCl solution through central vein while the control group were treated with 03% KCl solution. Both groups were infused at the speed of 1-15 g/h KCl. Responses to the treatment in two groups were  observed.ＲｅｓｕｌｔｓWhen the potassium concentration rose to 3.0 mmol/L, patients in experimental group spent 395±257 h, and 405±188 g KCl,and 115±25 ml liquid was infused, compared with 723±445 h, 836±378 g, 2054±1250 ml in control group. To relieve the pernicious arrhythmia caused by hypokalemia,the experiment group spent 122±035 h, compared with 255±086 h in the control group. All of the above figures had statistic difference between the two groups (P＜005). However, to raise the blood potassium to 45 mmol/L, the two groups patients had been infused with KCl 355±123 g and 416±15.5 g respectively, with no statistical difference (P＞005).ＣｏｎｃｌｕｓｉｏｎｓIn aged patients with severe hypokalemia, high concentration potassium chloride infusion with micropump through central vein was safe and effective.

Key words: hypokalemia, aged, microbump, central vein

中图分类号: